Prescribing, Procedures and Investigation Interpretation Flashcards
Things to think before prescribing drugs
Indication, contraindication, route, dose, interactions, adverse effects
What can metoclopramide cause in young women
Oculogyric crises are defined as spasmodic movements of the eyeballs into a fixed position, usually upwards. These episodes generally last minutes, but can range from seconds to hours. At the same time there is often increased blinking of the eyes and these episodes are frequently accompanied by pain.
Key parts to writing a prescription
Type of drug - PRN, regular, once off etc
Allergy box
Labelling kardex
Think of common abbreviations
Cross out any change in prescription with a reason and signed.
When to use verbal prescriptions
When emergency
Give 8 dirty drugs
Digoxin, warfarin, antiepileptics, antibiotics, antidepressants, antipscyhotics, theophylline and amidarone.
What can liver disease do to drug dosing
Can alter P450 enzymes
Reduce the amount of protein so decreases binding of drug making more drug free
Fluid overload due to low albumin
Avoid IM as increased bleeding
What can renal disease do to drug dosing
Dont give nephrotoxic drugs without speaking to specialist.
What drugs should never be given to children
Tetracyclines - bone staining
Aspirin - reye syndrome
What drugs are controlled drugs
Strong opioids
Amphetamine-like agents (ritalin and cocaine LA)
Ketamine
Benzodiazepines
Anabolic steroids
Give some causes of insomnia
Anxiety, stress, depression, mania, alcohol, pain, coughing, diuretics, restless leg syndrome, steroids SSRIs, aminophylline, benzos/opioids withdrawal, poor sleep hygiene
How to manage insomnia
Treat cause
Dose stimulants at the start of the day - steroids, SSRIs, aminophylline
Give sedatives at night - tricyclics, anti-histamines
Ear plugs, sleep hygiene, eye shades
Avoid caffeine late on
If persistent, treat with - hypnotics (zopiclone) for 5 or less days
How to manage insomnia
Treat cause
Dose stimulants at the start of the day - steroids, SSRIs, aminophylline
Give sedatives at night - tricyclics, anti-histamines
Ear plugs, sleep hygiene, eye shades
Avoid caffeine late on
If persistent, treat with - hypnotics (zopiclone) for 5 or less days
How to manage insomnia
Treat cause
Dose stimulants at the start of the day - steroids, SSRIs, aminophylline
Give sedatives at night - tricyclics, anti-histamines
Ear plugs, sleep hygiene, eye shades
Avoid caffeine late on
If persistent, treat with - hypnotics (zopiclone) for 5 or less days. Dont let them go home on them
When do steroids become long term and thus a addisonian crisis risk
> 3 weeks
Steroid conversion for 5mg of pred
Hydrocortisone 20mg
Methylpred - 4mg
dexamethasone 750 micrograms
How to reduce steroid therapy
5-10mg a week until 10mg then reduce by 5mg a week thereafter.
Presentation of C. diff
Usually older adults with unexplained fever
Recent C abx
Abdo pain
Watery diarrhoea
What scan should be considered in C. diff along with stool cultures
AXR - toxic megacolon
How is C.diff treated
Vanc or metronidazole then fidaxomicin if fail to repsond
ACEI S/E
Postural hypotension, renail impairment, hyperkalaemia, dry cough, taste disturbance and angiooedema and utricaria
When is NAC effective
8 hours or less after ingestion, discontinue if normal bloods
What is the antidote for heparin
Protamine
Can partially work on LMWH too
What is ranitidine
H2 antagonist
What drug does SSRI’s react with
MOA inhibitors
Tramadol