prescribing in renal disease

Question 1

state 3 roles of the kidney?

Answer 1

filter the blood to remove waste products
balance electrolyte and water content of the Body
secrete essential hormones

Question 2

what is chronic kidney disease defined as?

Answer 2

reduction of kidney function or structural damage present for over 3 months

Question 3

what is acute kidney damage defined as?

Answer 3

an acute drop in kidney function

Question 4

when is eGFR not an appropriate test to use?

Answer 4

In the elderly and those of muscle mass extremes

Question 5

what is the GFR in each stage of chronic kidney disease?

Answer 5

1 = 90 or over
2 = over 60
3 = over 30
4 = over 15
5 = under 15

Question 6

which medications should be held in acute kidney injury?

Answer 6

DAMN:
diuretics, ACEi, metformin, NSAIDS

Question 7

give 3 ways that renal impairment can effect drug administration?

Answer 7

risk of drug accumulation
increased drug half life
reduced drug efficacy