Prescribing in pregnancy

Question 1

This wonder drug was given as an anti-emetic to thousands of pregnant women and is still used in the treatment of leprosy and myeloma?

Answer 1

Thalidomide

Question 2

Pre conception treatment

Answer 2

Folic acid 400mcg daily for 3 months prior and first 3 months of pregnancy

Counselling for chronic condition:
Epilepsy, diabetes, hypertension

Question 3

When is there a risk of early miscarriage and teratogenic risk?

Answer 3

1st trimester

4th-11th week teratogenic risk greatest

Question 4

You should avoid drugs if possible unless maternal benefit outweights the risks to foetus in this trimester of pregnancy?

Answer 4

1st trimester

Question 5

Teratogenic effect of ACE inhibitors/ARB in pregnancy?

Answer 5

Renal hypoplasia

Question 6

Teratogenic effect of androgens in pregnancy?

Answer 6

virilisation of female foetus

Question 7

Teratogenic effect of antieplieptics in pregnancy?

Answer 7

cardiac, facial, limb , neural tube defects

Question 8

Teratogenic effect of cytotoxics in pregnancy?

Answer 8

multiple defects

abortion

Question 9

Teratogenic effect of lithium in pregnancy?

Answer 9

cardiovascular defects

Question 10

Teratogenic effect of methotrexate in pregnancy?

Answer 10

skeletal defects

Question 11

Teratogenic effect of retinoid in pregnancy?

Answer 11

ear, cardiovascular, skeletal defects

Question 12

Teratogenic effect of warfarin in pregnancy?

Answer 12

limb and facial defects

Question 13

Giving this type of drug close to delivery can cause respiratory depression

Answer 13

Opiates

Question 14

This drug can cause bleeding during pregnancy

Answer 14

Warfarin

Question 15

These drugs can cause withdrawal symptoms in babies after delivery

Answer 15

opiates

SSRI

Question 16

This drug caused vaginal carcinoma and urological malignancy in children whose mothers wee exposed to which drug?

Answer 16

Diethylstilbestrol

Question 17

These antiepleptic drugs should be avoided in pregnancy?

Answer 17

valproate

phenytoin

Question 18

This drug is not safe to use in diabetes during pregnancy

Answer 18

Sulfonylureas

Question 19

This drug is safe to use in diabetes during pregnancy

Answer 19

Insulin

Question 20

These drugs can be used to treat hypertension in pregnancy?

Answer 20

Labetalol
Methyldopa
Nifedipine MR

Question 21

These drugs can inhibit foetal growth in pregnancy

Answer 21

Beta blockers

Question 22

This drug is safe to use for nausea and vomiting in pregnancy?

Answer 22

Cyclizine

Question 23

This is the leading cause of maternal death in pregnancy?

Answer 23

venous thromboembolism

Question 24

Those with risk factors for VTE should be offered thromboprophylaxis with which drug?

Answer 24

LMWH

Question 25

This drug is teratogenic in early pregnancy and increases risk of haemorrhage in late pregnancy?

Answer 25

Warfarin

Question 26

This drug can cause neonatal hypothyroidism during breast feeding

Answer 26

Amiodarone

Question 27

This drug can cause bone marrow suppression during breast feeding

Answer 27

Cytotoxics

Question 28

This drug can cause drowsiness during breast feeding

Answer 28

Benzodiazepines

Question 29

This drug can suppress lactation during breast feeding

Answer 29

Bromocriptine

Question 30

This antibiotic can stain bones and teeth if given in pregnancy or early childhood?

Answer 30

Tetracycline

Question 31

This antiepileptic drug is associated with left lip and palate if taken during pregnancy

Answer 31

phenytoin

Question 32

This drug can cause vaginal adenocarcinoma if taken during pregnancy

Answer 32

stilbestrol

Question 33

This antieplipetic drug is associated with spina bifida and anencephaly

Answer 33

Valproate