Prescribing and Deprescribing Flashcards

1
Q

Why do we need to supply Anticipatory Medication?

A

“Just in case” medication

  • stress and worry can be avoided as patient can receive what they need, when they need it without delay
  • one of the most challenging situations for pts is access to meds “ out of hours”
  • discomfort for patient if lack of symptom control
  • distress for loved ones trying to get Rx dispensed
  • difficult for patient if suffering whilst medication is delayed
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2
Q

What common symptoms are seen towards the end of life and how to treat them?

A

Pain - Morphine or Diamorphine
Nausea and Vomitting - Cyclizine
Restless / Agitation - Midazolam
Secretions “Death Rattle” - Hyoscine Hydrobromide

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3
Q

Legal Requirements of a CD Prescription

A
  • Name
  • Form
  • Strength
  • Dose
  • Total quantity (both words and figures)
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4
Q

Problems with Polypharmacy

A
  • interactions
  • tablet burden
  • on medications with little or no benefit
  • side effect profile
  • complications
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5
Q

What circumstances should be considered before deprescribing?

A
  • life expectancy
  • treatment target (slow disease progression, prevent decline, symptom control)
  • how long does it take to see benefit of drug
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6
Q

Barriers to Deprescribing

A
  • limited time available
  • lack of clarity over whos “job” it is to deprescribe
  • concern around stopping meds initiated by a specialist
  • uncertainty about the ongoing benefits of a medication
  • withdrawal effects
  • worsening of symptoms
  • unclear prognosis and goals of care
  • concern that pt and family may see it as a sign of “giving up hope”
  • unwillingness or reluctance from the pts to change their meds
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7
Q

Process of Deprescribing

A
  1. Ensure a complete medication history is obtained
  2. Identify the indication for each drug
  3. Consider the potential for harm for each drug, for example the age of the patient, the number and types of medication and the patients comorbidities
  4. Consider the ‘risk versus benefit’ for each medication
  5. Identify medication suitable for deprescribing
  6. Discuss and explain changes with patient
  7. Deprescribe one medication at a time if possible
  8. Reassess the effects of deprescribing
  9. Continue deprescribing as appropriate
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8
Q

Reasons to consider deprescribing in palliative care

A
  • reduced adverse events
  • reduced cost
  • reduced tablet burden
  • enhanced quality of life
  • prioritisation of most essential medications
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9
Q

Reasons for deprescribing

  • Antihypertensives
  • Cardiac Drugs
  • Diabetic Meds
A
  • antihypertensives: body weight reduces and metabolism slows down, common for BP to fall
  • cardiac drugs: some drugs e.g. aspirin and statin treat risk rather than symptom
  • diabetic meds: weight loss and reduced metabolism reduces the need
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10
Q

Reasons for staying on chemotherapy

A
  • lengthen life

- symptomatic relief

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11
Q

When should you stop steroids in palliative care?

A
  • stop when unable to swallow because of decreased consciousness or profound weakness
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