Preoperative/Postoperative Care Flashcards

1
Q

allergies and meds not to give

A
  • egg: dont use propofol
  • shellfish: do not use IV iodinated contrast
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2
Q

risk assessment for cardiac disease

A
  • hx of MI, unstable angina, valvular dz, HTN, arrhythmias, and heart failure
  • if previous infarction there is a 5-10% risk of postop MI
  • if current unstable angina avoid elective surgeries
  • if stage III HTN control prior to surgery
  • if hx of rheumatic heart dz provide prophylactic abx tx
  • cardio clearance: 12 lead EKG, noninvasive stress testing
  • coronary revasc before noncardiac ops in pts with: significant left main coronary artery stenosis, stable angina with 3 vessel coronary dz, stable angina with 2 vessel dz, significant proximal left anterior descending coronary artery stenosis with either an ejection fraction <50% or ischemia on noninvasive testing, high-risk unstable angina or non-ST-segment elevation MI, or acute ST-elevation MI
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3
Q

risk assessment for pulmonary disease

A
  • hx of asthma, COPD
  • established risk factor for postop pulm complications (PPC): advanced age, elevated ASA class, congestive heart failure, fnal dependence, known COPD, malnutrition, alc abuse, and altered mental status, sleep apnea is an independent risk factor for PPC
  • smoking cessation also confers favorable effects on wound healing - stop smoking at least 1 mo before operations, ideally with programmatic support through formal counseling programs and possibly smoking cessation aids such as varenicline or transderm nicotine
  • postop pulm complications: hypoxia, atelectasis, PNA
  • aggressive postoperative pain management to promote ealry ambulation
  • incentive spirometry - insp mm training, deep insp, coughing, good oral hygiene
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4
Q

risk assessment for metabolic disease

A
  • hx of DM, adrenal insuff
  • blood gluc elevated preop in DM pts especially if physical trauma present with emotional and physiologic stress
    • elevated postop blood glucose levels in DM pts translate to progressively greater chances of SSI (surg site infxn) following cardiac ops, as well as a greater likelihood of post op infxn and prolonged hosp stays in pts with noncardiac ops
    • risk of SSI incrementally increase in a linear pattern with the degree of hyperglycemia, with levels greater than 140 being sole predictor of SSI
    • intravenous insulin is best for periop gluc control dt its rapid onset of action, short half-life, and immediate availability (as opposed to subcut absorption)
  • periop hyperlyc should be treated with IV short acting insulin or SQ sliding scale insulin
  • glycemic control: normal = 90-100 preferred, control with IV insulin; moderate = 120-200
  • postop monitoring for: hyperglyc or hypoglyc, infxn, poor healing and wound issues, CVD (double the risk for men, quad the risk, for women
  • obesity: contrary to popular belief, this is not a risk factor for most major adverse postop outcomes, except pulm embolism
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5
Q

functional capacity

A
  • Excellent (activities requiring >7 METs): carry 24lbs up 8 steps, carry objects that weigh 80lbs, outdoor work, recreation (ski, basketball, squash, handball, jog or walk 5mph)
  • moderate (>4 - <7 METs): sexual intercourse without stopping, walk at 4mph on level ground, outdoor work (garden, rake, pull weeds), recreation (roller skate, dance)
  • poor (<4 METs): shower or dress without stopping, make bed, dust, or wash dishes, walk at 2.5 mph on level ground, outdoor work (eg clean windows), recreation (golf or bowl)
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6
Q

risk stratification for periop thromboembolism

A
  • high: (>10%/y risk of ATE or >10%/mo risk of VTE)
    • mech hrt valve: any mech mitral valve, other aortic valve, recent (<6mo) stroke or TIA
    • afib: CHADs2 score of 5-6, recent (<3mo) stroke or TIA, rheumatic valvular dz
    • venous thromboembolism: recent (<3mo) VTE, severe thrombophilia
    • intervention: bridging anticoag w/ therapeutic dose SQ heparin or IV enoxaparin sodium (lovenox) - IPC + LMWH or low-dose SQ hep
    • pearls: if pt already on warf, hold 1 wk prior, place on lovenox, remain lovenox 1wk postop before returning to warf
  • moderate: (4-10%/y risk of ATE or 4-10%/mo risk of VTE)
    • mech hrt valve: bileaflet aortic valve and 1 of following - afib, prior stroke or TIA, HTN, DM, HF, age >75
    • afib: CHADs2 score of 3-4
    • VTE: within past 3-12mo, recurrent VTE, nonsevere thrombophilic conditions, active malig
    • intervention: bridge anticoag with tx dose SQ hep OR tx dose IV lovenox OR intermittent pneumatic compression devices
  • low: (<4%/y risk ATE or <2%/mo risk VTE)
    • mech hrt valve: bileaflet aortic valve without afib and no other risk factors for stroke
    • afib: CHADs2 score of 0-2 (and no prior stroke or TIA)
    • VTE: single VTE within past 12mo and no other RF
    • intervention: mech prophylaxis with intermittent pneumatic compression (IPC) devices
    • pearls: bridging anticoag with low-dose hep or no bridging
  • very low: intervention = early ambulation alone
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7
Q

risk assessment for renal dz

A
  • dialysis-dependent CKD - risk of complications (postop hyperK, PNA, fluid overload, bleeding) significantly increased - pts should undergo dialysis within 24 hrs before surg and lytes monitored immediately before and during postop period, monitor weight, I&Os, renal fn
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8
Q

risk assessment for hepatic dz

A
  • liver dz complications: hemorrhage, infxn, renal failure, encephalopathy, substantial mortality rate
  • elevated LFTs after major surg is common; transient, not associated with hepatic dysfn
  • ascites leads to wound dehiscence or hernias, hepatic encephalopathy is worsened by sedatives and analgesics, coagulopathy (give pts vitK +/- plasma transfusion)
  • postop: check plt number and fn (inc bleeding risk with low PLTs), check for lyte disturbs (especially hyperNa), risk for upper GI hemorrhage (esophageal or gastric varices), alcoholics (malnut potential for vit def (be aggressive with refeeding to prevent abnl in gluc metabolism and cardiac arrhythmia - alc withdrawal (1-5d, peak at 3d), prevent with benzos)
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9
Q

tobacco use or dependence

A
  • can dec fnal capacity and inc risk of bleeding, infxns, and wound dehiscence, hernia recurrence rate inc with tobacco use
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10
Q

substance abuse

A
  • in general, pts should be advised to refrain from taking illicit drugs for at least a couple weeks before an op
  • similarly, a hx of heavy alc consumption raises possibility of postop withdrawal syndrome (can be associated with significant morbidity and death)
  • ideally, pts should cease drinking alc for at least one wk before op
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11
Q

When to discontinue certain meds

A
  • Aspirin: continue if mod to high risk for coronary artery dz
  • oral anticoags: stopped 3-5d before (hep administered until 6hrs before surg - resume 36-48h postop)
  • cox-2: hold 2-3d before
  • DM meds: hold 1d prior
  • estrogen: hold 4-6wks prior dt inc risk postop DVT
  • HTN meds: continue or risk of periop MI
  • GI meds (H2, PPI): continue unchanged including day of surg
  • pulm meds: continue including day of surg
  • DC all herbs and vitamins
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12
Q

American Society of Anesthesiologists classification system

A
  • ASA 1: normal healthy pt
    • no organic, physiologic, or psych disturbs; excludes very young and very old; healthy with good exercise tolerance
  • ASA 2: pts with mild systemic dz
    • no fnal limitations; has well controlled dz of one body system; controlled HTN or DM without systemic effects, cigarette smoking without chronic obstructive pulm dz; mild obesity, pregnancy
  • ASA 3: pts with severe systemic dz
    • some fnal limitation; has a controlled dz of more than one body system or one major system; no immediate danger of death; controlled congestive heart failure (CHF), stable angina, former heart attack, poorly controlled HTN, morbid obesity, chronic renal failure; bronchospastic dz with intermittent sxs
  • ASA 4: pts with severe systemic dz that is a constant threat to life
    • has at least one severe dz that is poorly controlled or at end-stage; possible risk of death; unstable angina, system COPD, sxatic CHF, hepatorenal failure
  • ASA 5: moribund pts who are not expected to survive without the operation
    • not expected to survive >24h without surg; imminent risk of death; multiorgan failure, sepsis syndrome with hemodynamic instability, hypotherm, poorly controlled coagulopathy
  • ASA 6: declared brain-dead pt whose organs are being removed for donor purposes
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13
Q

Preop abx: GI

A
  • GI: involving entry into lumen of GI tract
    • pathogens: G- bacilli, G+ cocci
    • abx: cefazolin
  • Biliary:
    • open or lap: enteric G- bacilli, enterococci, clostridia
      • abx: cefazolin, cefotetan, cefoxitin, amp-sulbactam
    • lap: none
  • appendectomy: enteric G- bacilli, anaerobes, enterococci
    • abx: flagyl plus one of the following - cefoxitin, cefotetan, cefazolin
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14
Q

Preop abx: cardiac

A
  • Cardiac: coronary artery bypass, cardiac device insertion procedures (eg, pacemaker implantation), placement of ventricular assist devices
    • pathogens: staph aureus, staph epidermidis
    • abx: cefazolin, cefuroxime, vancomycin, clindamycin
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15
Q

preop abx: small intestine

A
  • nonobstructed: enteric G- bacilli, G+ cocci
    • abx: cefazolin
  • obstructed: enterig G- bacilli, anaerobes, enterococci
    • abx: flagyl plus one of the following - cefoxitin, cefotetan, cefazolin
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16
Q

preop abx: hernia repair

A
  • pathogens: aerobic G- organisms
  • 1st line abx: cefazolin
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17
Q

preop abx: colorectal

A
  • pathogens: enteric G- bacilli, anaerobes, enterococci
  • abx: flagyl plus one of the following - cefoxitin, cefotetan, cefazolin OR oral neomycin + erythromycin base or flagyl
18
Q

preop abx: genitourinary

A
  • pathogens: enteric G- bacilli, enterococci
  • abx: ciprofloxacin or bactrim
19
Q

preop abx: OB/GYN

A
  • hysterectomy (abd, vag, lap, or robotic), urogynecology procedures including those involving mesh
    • abx: cefazolin, cefoxitin, cefotetan
      • alternatives: amp-sulbactam, clindamycin or vanco with (gent, aztreonam, FQ), flagyl plus (gentamicin, FQ)
  • cesarean: cefazolin
  • abortion (surg): doxy
  • hysterosalpingogram or chromotubation: doxy
  • lap, transcervical procedures, hysteroscopy, IUD insertion, endometrial bx: NONE
20
Q

preop abx: neurosurg

A
  • elective craniotomy, CSF fluid shunting procedures, implantation of intrathecal pumps
    • pathogens: staph aureus, s epidermidis
    • abx: cefazolin, vanco, or clinda
21
Q

preop abx: head and neck surg

A
  • clean surg: no pathogens and no abx needed
  • clean with prostehtic placement: staph aureus, s epidermidis, streptococci
    • abx: cefazolin, cefuroxime, vanco, clindamycin
  • clean contaminated: anaerobes, enteric gram-neg bacilli, s. aureus
    • abx: cefazolin + flagyl; cefuroxime + flagyl; amp-sulbactam; clindamycin
22
Q

preop abx: ortho

A
  • clean (hand, knee, or foot with no implant of foreign material): no pathogens, no abx
  • spinal procedures, hip fracture, internal fixation, total jnt replacement: staph aureus, s epidermidis
    • abx: cefazolin, vanco, or clinda
23
Q

preop abx: thoracic

A
  • thoracic (noncardiac) procedures [lobectomy, pneumonectomy, lung resection, thoractomy]: staph aureus, s epidermidis, strep, enteric G- bacilli
    • abx: cefazolin, vanco, clinda, amp-sulbactam
24
Q

preop abx: vascular

A
  • arterial surg w prosthesis, abd aorta, or groin incision: staph aureus, s epiderm, enteric G- bacilli
    • abx: cefazolin, vanco, clinda
  • lower extrem amputation: s aureus, s epiderm, enteric G- bacilli, clostridia
    • abx: cefazolin, vanco, clinda
25
Q

preop abx: percutaneous

A
  • angiography, angioplasty, thrombolysis, arterial closure device placement, stent placement, superficial venous insuff tx, IVC filter placement: s auerus, s epiderm
    • abx: none, cefazolin if high risk (immunocomp, chemo, hx of catheter infxn), for PCN allergy vanco or clinda
  • endograft: s aureus, s epiderm
    • abx: cefazolin, if PCN allergy vanco or clinda
26
Q

preop abx: breast

A
  • reduction mammoplasty, mammoplasty, lumpectomy, mastectomy, axillary node dissection: no pathogens, no abx
  • breast CA procedures: s aureus, s epiderm, streptococci
    • abx: cefazolin, vanco, clinda
27
Q

postop fever

A
  • immediate onset (in OR or within hours after surg): meds or blood product exposure during preop, surg, or immediately postop; trauma suffered, infxn present prior to surg
    • presenting sign: hoTN, rash
  • acute onset (w/in first week after surg): 5Ws
  • subacute onset (1-4wks postop): SSI, central venous cath, abx associated diarrhea, febrile drug rxn
  • delayed (more than 1mo after surg): dt infxn (viral), including CMV, hep, HIV, parasite
28
Q

5Ws

A
  • Wind (POD 1-2): PNA, aspiration, PE, atelectasis
  • Water (POD 3-5): UTI (more common with GU procedures and chronic indwelling catheters)
  • Walking (POD 4-6): DVT or PE
  • Wound (POD 5-7): surgical site infxn (SSI)
  • Wonder drugs (POD 7+): drug fever, infxn from lines, rxn to blood products
29
Q

Atelectasis

A
  • MC POSTOP COMPLICATION
  • RF: elderly, overweight, smokers, resp dz, fever w/in 48hrs
  • dec lung tissue compliance, impaired regional vent, retained airway secretions, and/or postop pain interfering with breathing and coughing
  • Obstruction by secretions (COPD), intubation or anesthesia
  • nonobstructive causes: closure of bronchioles (<1mm)
  • sxs: fever, inc work of breathing
  • signs: elevation of diaphragm, scattered rales, dec breath sounds in area, dullness to percussion, tachypnea, tachycardia, hypoxemia
  • dx: V/P mismatch, CXR abnl (findings dependent on location)
  • tx: chest percussion, coughing, nasotrach suction (fever dec with reexpansion of lung), bronchodilators and mucolytics via neb for COPD, trial of CPAP if hypoxemia and inc resp effort
  • prevention: early ambulation, fequent position changes, cough, incentive spirometry
  • prognosis: if atelectasis persists beyond 72h, PNA will likely occur
30
Q

PNA

A
  • tends to occur within 5d postop, highest risk = peritoneal infxn, prolonged vent support
  • RF: atelectasis, asp, copious secretions
  • caused by s aureus, G- bacilli (E. coli, pseudo, klebs)
  • sxs: fever, inc secretions
  • signs: tachypnea, physical changes suggestive of pulm congestion, hypercapnia)
  • dx: CXR localized parenchymal consolidation, CBC leukocytosis or leukopenia, sputum must be obtained by endotracheal suctioning
  • tx: clear secretions, empiric abx, no changes in incidence with pain control or prophylactic abx
  • prevention: early ambulation, frequent position changes, cough, incentive spirometry
  • prognosis: mortality = 20-40%
31
Q

phlebitis

A
  • inflamm at entry site dt needle or catheter, MCC fever after POD 3, MC in lower extremity veins
  • sxs: swelling
  • signs: erythema, tenderness, edema, induration
  • tx: remove catheters at earliest signs
  • prevention: aseptic technique during insertion, frequent change of tubing (48-72h), rotation of insertion sites (q4d), use silastic catheters (least reactive), and hypertonic solns in veins with substantial flow
  • suppurative phelb: mc bug = staph, presence of infxed thrombus around indwelling cath
    • signs: local inflamm + pus from venupuncture site, high fever
    • dx: + blood cx
    • tx: excise affected vein, extend incision prox to first open collateral, leave wound open
32
Q

pulm edema

A
  • postop cardio edema: occurs within 36h
    • RF: preexisting hrt dz and too much IVF
  • MCC postop noncardio edema: neg pressure pulm edema (laryngospasm, upper airway obst following extubation)
    • RF: obesity, short neck, OSA< acromegaly
  • sxs: rapid onset SOB at rest, pink, frothy sputum
  • signs: crackles, wheezing, S3 gallop, elevated JVP, periph edema, tachypnea, tachycard, severe hypoxemia
  • complications: pulm hemorrhage, hemoptysis
  • dx: CXR (if cardio - enlarged cardio silhouette, perihilar alveolar infiltrates; if noncardio - normal heart size, uniform alveolar infiltrates), echo, EKG, BNP, Swan-Ganz catheter
  • tx: O2 and vent (mech vent with adequate O2 delivery, PEEP), reduce preload (loop diuretics, nitrates, morphine, ACEi)
33
Q

postop urinary retention (POUR)

A
  • cant pee after anesthesia
  • RF: old, male, hx urinary retention, neuro dz, hx pelvic surg
    • procedural: anorectal surg, joint arthroplasty, hernia repair, incont surg
  • sxs: bladder fullness, lower abd discomfort
  • dx: bladder US, cath
  • tx: if cant void 4h after surg and 600+mL detected on US - one time bladder cath, if volume drained >400mL, leave cath in place, remove before dc
  • prophylactic cath for ops 3+h or high IVF volumes
34
Q

postop UTIs

A
  • RF: preexisting contamination of UT, urinary retention, instrumentation
  • sxs: dysuria, mild fever
    • sxs of pyelo: high fever, flank tenderness, ileus
  • dx: examine urine and obtain cx
  • tx: adequate hydration, proper drainage of bladder, and abx
35
Q

Venous thromboembolism

A
  • virchow’s triad: hypercoagulable state, stasis, vessel damage
  • trama pts, cancer ops, dissection of pelvis
  • nonmodifiable RF: thrombophilia, prior VTE, CHF, chronic lung dz, paralytic stroke, malig, SCI, age >40, varicosities
  • modifiable RF: type of surg, mech vent, major trauma, central lines, chemo, HRT, preg, immobility, obesity
36
Q

pulmonary embolism RF and sxs

A
  • thrombus embolizes to pulm vasc tree via RV and pulm artery → causes cor pulmonale (severe)
  • MC site → distal to bifurcation of main pulm artery in main lobar, segmental, or subsegmental branches of pulm a; saddle → bifurcation of main pulm a
  • incidence = M>F
  • RF: age >60y, malig, prior hx, hypercoag, prolonged immobilization or bed rest, long-distance travel, cardiac dz, obesity, nephrotic syndrome, major surg or major trauma, preg, E use (OCP)
  • Virchows triad: hypercoag, venous stasis, endothelial injury
  • sxs: dysp (at rest or with exert), pleuritic chest pain (worse with insp), cough, calf or thigh pain or swelling, wheezing, hemoptysis, syncope
  • signs: tachypnea, tachycardia, rales, dec breath sounds, accentuated pulm component of S2, JVD, fever
  • signs of RVHF: hypoTN and JVD, R-sided S3, parasternal lift, cyanosis
37
Q

pulmonary embolism diagnostics and tx

A
  • dx: CXR, D dimer (if low clinical suspicion - do first), EKG (tachy and non specific ST and T wave changes - <10% shows S1Q3T3), + CT pulm angiogram w/ contrast (GOLD STANDARD), VQ scan, normal CXR required prior → test of choice in pregnancy, contrast allergy, and pts with renall insuff, doppler US of lower extrem, Increased A-a gradient, ABG shows resp alkalosis
  • Prevention: early ambulation, elastic graduated compression stockings
  • tx: O2, hemodynamically unstable (IVF, vasopressors: NE), anticoag
  • prognosis: recurrence common
  • complications in pts with PE who survive: recurrent PE or pulm HTN
38
Q

DVT RF, sxs

A
  • 25% postop pts will develop DVT w/o proph
  • ASA not supported as single agent for proph
  • RF: hx of immobilization, recent surg or trauma, obesity, previous VTE, malig, OCP or HRT use, preg or postpartum, age >65, stroke with hemiplegia or immobility, family hx of VT, HF or IBD
  • proximal DVT: located in popliteal, femoral, or iliac veins
  • isolated distal DVT: located below the knee, confined to calf veins (peroneal, post, ant tibial, musc veins)
  • sxs: lower extrem swelling, unilateral or bilater leg pain, warmth
  • signs: hypoxia, HR >100, erythema, pitting edema, dilated superficial veins, tenderness, warmth, local inguinal mass, larger calf diameter (if unilateral), homan’s sign (calf pain with passive dorsiflexion is unreliable)
39
Q

DVT dx and tx

A
  • dx: CBC, Chem, LFTs, coag, PTP using well’s criteria, d-dimer if low suspicion (positive is >500ng/mL), compression US with doppler (preferred) - preferred primary eval for pts with prior DVT
    • treat if: prox DVT identified, distal DVT identified and pt meets criteria for tx fo distal DVT
  • tx:
    • anticoag: for pts with first DVT, anticoag x3mo
    • IVC filter: when risk bleeding outweighs risk VTE, CI to anticoag (active bleeding or diathesis, PLT <50, high risk surg or procedure, trauma, hx ICH
    • malig: pts with Ca tx with LMWH for initial and long term management unless CI or renal insuff (CrCl <30)
    • preg: adjusted dose SQ LMWH for initial and long-term managment, dc 24h prior to predicted delivery; neuraxial anesthsia use inc risk for spinal hematoma, temporary IVC filter can be place for pts w prior VTE, restart hep 12h after csection or 6h after vag deliv
    • thrombectomy: pts with massive iliofem DVT or fail anticoag tx, for preg women whom risk of life threatening PE is high
  • prevention: early ambulation, compression stockings x 2y, start after anticoag initiated
40
Q

surgical site infection (SSI)

A
  • RF: systemic factors (DM, immunosuppression, obesity, smoking, malnutrition, previous radiation), local factors (surgical wound classification and techniques)
  • clinical dx: pain, warmth, erythema, drainage through incision
  • tx: primary source control, abx prophylaxis
  • prevention: skin prep, maintain sterility, judicious use cautery, respect dissection planes, approximate tissue neatly, administer preop abx
41
Q

Fluid or volume disorders

A
  • 1% risk AKI postop, 10-30%