Preoperative management Flashcards
What are the aims of pre operative assessment?
Informed consent
Assess risk vs. benefits
Optimise fitness of patient
Check anaesthesia / analgesia type c¯ anaesthetist
What pre operative checks are carried out?
OP CHECS
Operative fitness: cardiorespiratory comorbidities
Pills
Consent
History
MI, asthma, HTN, jaundice
Complications of anaesthesia: DVT, anaphylaxis
Ease of intubation: neck arthritis, dentures, loose teeth
Clexane: DVT prophylaxis
Site: correct and marked
What are pre operative considerations for anti-coagulants?
Balance risk of haemorrhage c¯ risk of thrombosis
Avoid epidural, spinal and regional blocks
What are pre operative considerations for anti epileptic drugs?
Give as usual
Post-op give IV or via NGT if unable to tolerate orally
What are pre operative considerations for OCP or HRT?
Stop 4wks before major / leg surgery
Restart 2wks post-op if mobile
How many units of blood should be cross matched for a gastrectomy?
4
How any units of blood should be cross matched for AAA?
6
When should a chest x ray be carried out as a pre op investigation?
cardiorespiratory disease/symptoms, >65yrs
When should an ECG be carried out as a pre op investigation?
HTN, Hx of cardiac disease, >55yrs
How long should a patient be NBM prior to surgery?
≥2h for clear fluids, ≥6h for solids
What are the risks of bowel prep pre surgery?
Liquid bowel contents spilled during surgery
Electrolyte disturbance
Dehydration
↑ rate of post-op anastomotic leak
What are the options for bowel prep pre surgery?
Picolax: picosulfate and Mg citrate
Klean-Prep: macrogol
In what surgeries are prophylactic abx used?
GI surgery (20% post-op infection if elective)
Joint replacement
How is DVT risk managed for low, medium and high risk?
Low risk: early mobilisation
Med: early mobilisation + TEDS + 20mg enoxaparin
High: early mobilisation + TEDS + 40mg enoxaparin +
intermittent compression boots perioperatively.
What are the ASA grades?
- Normally healthy
- Mild systemic disease
- Severe systemic disease that limits activity
- Systemic disease which is a constant threat to life
- Moribund: not expected to survive 24h even c¯ op
How should insulin dependent DM patients be managed surgically?
Put pt. first on list and inform surgeon and anaesthetist
Some centres prefer to use GKI infusions
Sliding scale may not be necessary for minor ops
Put pt. first on list and inform surgeon and anaesthetist
Some centres prefer to use GKI infusions
Sliding scale may not be necessary for minor ops
How should NIDDM patients be managed surgically?
If glucose control poor (fasting >10mM): treat as IDDM
Omit oral hypoglycaemics on the AM of surgery
Eating post-op: resume oral hypoglycaemics c¯ meal
No eating post-op
Check fasting glucose on AM of surgery
Start insulin sliding scale
Consult specialist team ore. restarting PO Rx
Diet Controlled
Usually no problem
Pt. may be briefly insulin-dependent post-op
Monitor CPG
What are the risks of steroids in a surgical patient?
Poor wound healing
Infection
Adrenal crisis
How should patients taking steroids be managed surgically?
Need to ↑ steroid to cope c¯ stress
Consider cover if high-dose steroids w/i last yr
Major surgery: hydrocortisone 50-100mg IV c¯ pre-med
then 6-8hrly for 3d.
Minor: as for major but hydrocortisone only for 24h
What are the risks of surgery in a jaundiced patient?
Pts. c¯ obstructive jaundice have ↑ risk of post-op renal
failure need to maintain good UO.
Coagulopathy
↑ infection risk: may → cholangitis
How should jaundiced patients be managed pre operatively?
Avoid morphine in pre-med
Check clotting and consider pre-op vitamin K
Give 1L NS pre-op (unless CCF) → moderate diuresis
Urinary catheter to monitor UPO
Abx prophylaxis: e.g. cef+met
How should jaundiced patients be managed intraop.?
Hrly UO monitoring
NS titrated to output
How should jaundiced patients be managed post op?
Intensive monitoring of fluid status
Consider CVP + frusemide if poor output despite NS
What should be considered in anti-coag patients?
Very minor surgery may be undertaken w/o stopping
warfarin if INR <3.5.
Avoid epidural, spinal and regional blocks if
anticoagulated,
In general, continue aspirin/clopidogrel unless risk of
bleeding is high – then stop 7d before surgery
How should patients with low thromboembolic risk be managed surgically?
Stop warfarin 5d pre-op: need INR <1.5
Restart next day
How should patients with high thromboembolic risk be managed surgically?
Need bridging c¯ LMWH Stop warfarin 5d pre-op and start LMWH Stop LMWH 12-18h pre-op Restart LMWH 6h post-op Restart warfarin next day Stop LMWH when INR >2
How should emergancy surgery in pts anticoagulated be managed?
Discontinue warfarin
Vit K .5mg slow IV
Request FFP or PCC to cover surgery
What are the risks of COPD to surgery?
Basal atelectasis
Aspiration
Chest infection
What should be done pre op for pts with COPD?
CXR
PFTs
Physio for breathing exercises
Quit smoking (at least 4wks prior to surgery)
What are the aims of anaesthesia?
hypnosis, analgesia, muscle relaxation
What are the contraindications to regional anaesthesia?
local infection, clotting abnormality
Complication of propofol induction
cardio respiratory depression
complication of intubation
Oro-pharyngeal injury c¯ laryngoscope
Oesophageal intubation
Complication of loss of pain sensation
Urinary retention
Pressure necrosis
Nerve palsies
Complication of loss of muscle power?
Corneal abrasion
No cough → atelectasis + pneumonia
What is malignant hyperpyrexia?
Rare complication ppted by halothane or suxamethonium
AD inheritance
Rapid rise in temperature + masseter spasm
Rx: dantrolene + cooling
Why is analgesia necessary post op?
Pain → autonomic activation → arteriolar constriction →
↓ wound perfusion → impaired wound healing
Pain → ↓ mobilisation → ↑ VTE and ↓ function
Pain → ↓ respiratory excursion and ↓ cough →
atelectasis and pneumonia
Humanitarian considerations
What are the pre op options for analgesia?
Epidural anaesthesia: e.g. c¯ bupivacaine
What are the end op options for analgesia?
Infiltrate wound edge c¯ LA
Infiltrate major regional nerves c¯ LA
What are the post op options for pain relief?
1. Non-opioid ± adjuvants Paracetamol NSAIDs Ibuprofen: 400mg/6h PO max Diclofenac: 50mg PO / 75mg IM
- Weak opioid + non-opioid ± adjuvants
Codeine
Dihydrocodeine
Tramadol - Strong opioid + non-opioid ± adjuvants
Morphine: 5-10mg/2h max
Oxycodone
Fentanyl
What are the aims of enhanced recovery after surgery?
Optimise pre-op preparation for surgery
Avoid iatrogenic problems (e.g. ileus)
Minimise adverse physiological / immunological responses
to surgery
↑ cortisol and ↓ insulin (absolute or relative)
Hypercoagulability
Immunosuppression
↑ speeded of recovery and return to function
Recognise abnormal recovery and allow early intervention
How can a patient be optimised pre surgery under the enhanced recovery programme?
Aggressive physiological optimisation
Hydration
BP (↑ / ↓)
Anaemia
DM
Co-morbidities
Smoking cessation: ≥4wks before surgery
Admission on day of surgery, avoidance of prolonged fast
Carb loading prior to surgery: e.g. carb drinks
Fully informed pt., encouraged to participate in recovery
How are patients on enhanced recovery programmes managed intra op?
Short-acting anaesthetic agents
Epidural use
Minimally invasive techniques
Avoid drains and NGTs where possible
How are patients on enhanced recovery programmes managed post op?
Aggressive Rx of pain and nausea
Early mobilisation and physiotherapy
Early resumption of oral intake (inc. carb drinks)
Early discontinuation of IV fluids
Remove drains and urinary catheters ASAP
What are the immediate complications of surgery?
Intubation → oropharyngeal trauma
Surgical trauma to local structures
Primary or reactive haemorrhage
What are the early complications of surgery?
Secondary haemorrhage VTE Urinary retention Atelectasis and pneumonia Wound infection and dehiscence Antibiotic association colitis (AAC)
What are the late complications of surgery
Scarring
Neuropathy
Failure or recurrence
How is surgical hemorrhage classified
Primary: continuous bleeding starting during surgery
Reactive
Bleeding at the end of surgery or early post-op
2O to ↑ CO and BP
Secondary
Bleeding >24h post-op
Usually due to infection
What are the causes of post op urinary retention?
Drugs: opioids, epidural/spinal, anti-AChM
Pain: sympathetic activation → sphincter contraction
Psychogenic: hospital environment
What are the risk factors for post op urinary retention?
Male ↑ age Neuropathy: e.g. DM, EtOH BPH Surgery type: hernia and anorectal
How is post op urinary retention managed?
Conservative Privacy Ambulation Void to running taps or in hot bath Analgesia Catheterise ± gent 2.5mg/kg IV stat TWOC = Trial w/o Catheter If failed, may be sent home c¯ silicone catheter and urology outpt. f/up.
What is pulmonary atelectasis?
Occurs after every nearly every GA
Mucus plugging + absorption of distal air → collapse
What are the causes of pulmonary atelectasis?
Pre-op smoking
Anaesthetics ↑ mucus production ↓ mucociliary
clearance
Pain inhibits respiratory excursion and cough
How does pulmonary atelectasis present?
w/i first 48hrs
Mild pyrexia
Dyspnoea
Dull bases c¯ ↓AE
How is pulmonary atelectasis managed?
Good analgesia to aid coughing
Chest physiotherapy
How are operative wound infections managed?
Clean: incise uninfected skin w/o opening viscus
Clean/Cont: intra-op breach of viscus (not colon)
Contaminated: breach of viscus + spillage or opening of
colon
Dirty: site already contaminated – faeces, pus, trauma
What are the risk factors for wound infection?
Pre-operative ↑ Age Comorbidities: e.g. DM Pre-existing infection: e.g. appendix perforation Pt. colonisation: e.g. nasal MRSA Operative Op classification and wound infection risk Duration Technical: pre-op Abx, asepsis Post-operative Contamination of wound from staff
How are wound infections managed?
Regular wound dressing
Abx
Abscess drainage
How does wound dehiscence present?
Occurs ~10d post-op
Preceded by serosanguinous discharge from wound
What are the risk factors for wound dehiscence?
Pre-Operative Factors ↑ age Smoking Obesity, malnutrition, cachexia Comorbs: e.g. BM, uraemia, chronic cough, Ca Drugs: steroids, chemo, radio Operative Factors Length and orientation of incision Closure technique: follow Jenkin’s Rule Suture material Post-operative Factors ↑ IAP: e.g. prolonged ileus → distension Infection Haematoma / seroma formation
How is wound dehiscence managed?
Replace abdo contents and cover c¯ sterile soaked gauze IV Abx: cef+met Opioid analgesia Call senior and arrange theatre Repair in theatre Wash bowel Debride wound edges Close c¯ deep non-absorbable sutures (e.g. nylon) May require VAC dressing or grafting
What are the complications of cholecystectomy?
Conversion to open: 5% CBD injury: 0.3% Bile leak Retained stones (needing ERCP) Fat intolerance / loose stools
What are the complications of inguinal hernia repair?
Early Haematoma / seroma formation: 10% Intra-abdominal injury (lap) Infection: 1% Urinary retention Late Recurrence (<2%) Ischaemic orchitis: 0l5% Chronic groin pain / paraesthesia: 5%
What are the complications of appendectomy?
Abscess formation
Fallopian tube trauma
Right hemicolectomy (e.g. for carcinoid, caecal
necrosis)
What are the complications of colonic surgery?
Early Ileus AAC Anastomotic leak Enterocutaneous fistulae Abdominal or pelvic abscess Late Adhesions → obstruction Incisional hernia
What causes post op ileus?
Bowel handling
Anaesthesia
Electrolyte imbalance
How does post op ileus present?
Distension
Constipation ± vomiting
Absent bowel sounds
How is post op ileus managed?
IV fluids + NGT
TPN if prolonged
What are the complications of anorectal surgery
Anal incontinence
Stenosis
Anal fissure
What are the complications of small bowel surgery?
Short gut syndrome (≤250cm)
What are the complications of splenectomy?
Gastric dilatation (2O gastric ileus)
Prevent c¯ NGT
Thrombocytosis → VTE
Infection: encapsulated organisms
What are the complications of arterial surgery?
Thrombosis and embolization
Anastomotic leak
Graft infection
What are the complications of aortic surgery?
Gut ischaemia Renal failure Aorto-enteric fistula Anterior spinal syndrome (paraplegia) Emboli → distal ischaemia (trash foot)
What are the complications of breast surgery?
Arm lymphoedema
Skin necrosis
Seroma
What are the complications of prostatectomy?
Urinary incontinence
Erectile dysfunction
Retrograde ejaculation
Prostatitis
What are the complications of thyroidectomy?
Wound haematoma → tracheal obstruction Recurrent laryngeal N. trauma → hoarse voice Transient in 1.5% Permanent in 0.5% R commonest (more medial) Hypoparathyroidism → hypocalcaemia Thyroid storm Hypothyroidism
What are the complications of tracheostomy?
Stenosis
Mediastinitis
Surgical emphysema
What are the complications of fracture repair?
Mal-/non-union
Osteomyelitis
AVN
Compartment syndrome
What are the complications of hip replacement?
Deep infection VTE Dislocation Nerve injury: sciatic, SGN Leg length discrepancy
What are the complications of cardio thoracic surgery?
Pneumo-/haemo-thorax
Infection: mediastinitis, empyema
What are the causes of post op pyrexia?
Early: 0-5d post-op Blood transfusion Physiological: SIRS from trauma: 0-1d Pulmonary atelectasis:24-48hr Infection: UTI, superficial thrombophlebitis, cellulitis Drug reaction
Delayed: >5d post-op Pneumonia VTE: 5-10d Wound infection: 5-7d Anastomotic leak: 7d Collection: 5-20d
What should be examined in a post op febrile patient?
Observation chart, notes and drug chart Wound Abdo + DRE Legs Chest Lines Urine Stool
What investigations should be carried out in a febrile post op patient?
Urine: dip + MCS
Blood: FBC, CRP, cultures ± LFTs
Cultures: wound swabs, CVP tip for culture
CXR
What are the causes of post op pneumonia
Anaesthesia → atelectasis
Pain → ↓ cough
Surgery → immunosuppression
What is the management of post op pneumonia?
Chest physio: encouraging coughing
Good analgesia
Abx
How does a collection present?
Malaise
Swinging fever, rigors
Localised peritonitis
Shoulder tip pain (if subphrenic)
What are the common locations for collections?
Pelvic: present @ 4-10d post-op Subphrenic: present @ 7-21d post-op Paracolic gutters Lesser sac Hepatorenal recess (Morrison’s space) Small bowel (interloop spaces)
What are the investigations carried out for collections?
FBC, CRP, cultures
US, CT
Diagnostic lap
What is the management for collections?
abx
drainage/washout
What is cellulitis?
Acute infection of the subcutaneous connective tissue
What are the typical causes of cellulitis?
β-haemolytic Streps + staph. aureus
how does cellulitis present
Pain, swelling, erythema and warmth
Systemic upset
± lymphadenopathy
What are the risk factors for DVT?
Virchows Triad
Blood Contents Surgery → ↑ plats and ↑ fibrinogen Dehydration Malignancy Age: ↑
Blood Flow
Surgery
Immobility
Obesity
Vessel Wall
Damage to veins: esp. pelvic veins
Previous VTE
What are the signs of DVT?
Peak incidence @ 5-10d post-op
65% of below knee DVTs are asymptomatic
Calf warmth, tenderness, erythema, swelling
Mild pyrexia
Pitting oedema
What investigations should be done in DVT
D-Dimers: sensitive but not specific Compression US (clot will be incompressible) Thrombophilia screen if: No precipitating factors Recurrent DVT Family Hx
how are dvts diagnosd?
- Assess probability using Wells’ Score
- Low-probability → perform D-dimers
Negative → excludes DVT
Positive → Compression US - Med / High probability → Compression US
How are DVTs managed?
Anticoagulate Therapeutic LMWH: enoxaparin 1.5mg/kg/24h SC Start warfarin using Tait model: 5mg OD for first 4d Stop LMWH when INR 2.5 Duration Below knee: 6-12wks Above knee: 3-6mo On-going cause: indefinite
Graduated Compression Stockings
Consider for prevention of post-phlebitic syndrome
How are DVTs prevented?
Pre-Op Pre-op VTE risk assessment TED stockings Aggressive optimisation: esp. hydration Stop OCP 4wks pre-op
Intra-Op
Minimise length of surgery
Use minimal access surgery where possible
Intermittent pneumatic compression boots
Post-Op LMWH Early mobilisation Good analgesia Physio Adequate hydration
What are the causes of post op hypoxia?
Previous lung disease Atelectasis, aspiration, pneumonia LVF PE Pneumothorax (e.g. due to CVP line insertion) Pain → hypoventilation
What investigations should be done in a post op hypoxic patient
FBC, ABG
CXR
ECG
What are the causes of post op reduced UO?
Post-renal Commonest cause Blocked / malsited catheter Acute urinary retention Pre-renal: hypovolaemia Renal: NSAIDs, gentamicin Anuria usually = blocked or malsited catheter Oliguria usually = inadequate fluid replacement
What is the management of post op reduced UO
Post Renal
Commonest cause
Blocked / malsited catheter
Acute urinary retention
Pre-renal: hypovolaemia
Renal: NSAIDs, gentamicin
Anuria usually = blocked or malsited catheter
Oliguria usually = inadequate fluid replacement
How is post op reduced UO managed?
Information
Op Hx
Obs chart: UO
Drug chart: nephrotoxins
Examination
Assess fluid status
Examine for palpable bladder
Inspect drips, drains, stomas, CVP
Action
Flush c¯ 50ml NS and aspirate back
Fluid challenge
What are the causes of post op N and V?
Obstruction
Ileus
Emetic drugs: e.g. opioids
What are the causes of post op decreased sodium?
S(I)ADH: pain, nausea, opioids, stress
Over administration of IV fluids
How should post op decreased sodium be managed?
Acute: 1mM/h
Chronic:15mM/d
What is the immediate management for post op hypotension
Tilt bed head down, give O2
Assess fluid status
What are the causes of post op hypotension?
CHOD
Cardiogenic
MI
Fluid overload
Hypovolaemia
Inadequate replacement of fluid losses
Haemorrhage
Obstructive
PE
Distributive
Sepsis
Neurogenic shock
How is post op hypotension managed?
Hypovolaemia → fluid challenge 250-500ml colloid over 15-30min Haemorrhage → return to theatre Sepsis → fluid challenge, start Abx Overload → frusemide Neurogenic → NA infusion
What are the causes of post op hypertension?
Pain
Urinary retention
Previous HTN
How is post op hypertension managed?
Rx cause
May use labetalol 50mg IV every 5min (200mg max)
What are the common causes of acute confusional state?
DELIRIUM
Drugs: opiates, sedatives, L-DOPA Eyes, ears and other sensory deficits Low O2 states: MI, stroke, PE Infection Retention: stool or urine Ictal Under- hydration / -nutrition Metabolic: Na, AKI, glucose, EtOH withdrawal
What is the management of acute confusional state?
May need sedation: midazolam / haldol
Nurse in well-lit environment
Rx cause