{Prenatal screening

Question 1

Which prenatal screening test can be done between the 10th and 14th week of the first trimester

Answer 1

1. Fetal free cell dna
2. NT
3. Maternal serum PAPP-A and HCG

Question 2

of the 3 first trimester fetal screening testing offered which test screen for aneuploidy

Answer 2

Fetal free cell dna

Maternal serum PAPP-A and HCG

Question 3

The NT test screens for what fetal disorders

Answer 3

1. Aneuploidy

2. congenital anomalies

Question 4

When is the fetal anatomic screen performed

Answer 4

The fetal anatomy screen is done between 15 to 23 weeks

Question 5

What does the anatomic screening test screen for?

Answer 5

1. Aneuploidy
2. NTDs
3. congenital anomalies

Question 6

Maternal serum screen also known as the quad screen is done when, during what trimester

Answer 6

The quad screen is done during the second trimester

Question 7

what 4 serum test are included in the quad screen

Answer 7

1. AFP
2. Estroil
3. hCG
4. inhibin A

Question 8

What abnormalities does quad screen, screen for

Answer 8

1. aneuploidy
2. NTD
3. Congenital anomalies

Question 9

During what weeks gestation is the quad screen done?

Answer 9

15-18 weeks

Question 10

What does an anomaly scan screen for

Answer 10

1. aneuploidy
2. NTD
3. congenital anomalies

Question 11

when is the fetal scan done during what weeks gestation

Answer 11

the fetal scan is done between the 15th and 23 weeks optimal time is 18 weeks

Question 12

What is an integrated screen

Answer 12

An integrated screen combines a first trimester and second trimester screening as an integrated risk assessment

Question 13

What does the integrated screen, screen for

Answer 13

1. Aneuploidy
2. NTD
3. Congenital anomalies

Question 14

How does the integrated and sequential screen differ

Answer 14

The sequential screen gives the mother/father the results in stages. The parents are given the results after the results are provided, the first trimester results are given in the first trimester and then the screening serum results are given at they’re available in the second trimester

Question 15

When is fetal cell free DNA done

Answer 15

anytime after 10 weeks to 14 weeks but can be done up until the time of delivery

Question 16

DURING WHAT TRIMESTER CAN CVS TESTING BE DONE

Answer 16

1 ST TRIMESTER BETWEEN 10-14 WEEKS GESTATION

Question 17

WHEN CAN AN AMNIOCENTESIS BE DONE

Answer 17

IN THE 2ND TRIMESTER BETWEEN 15 AND 22 WEEKS

Question 18

WHAT IS PAPP-A

Answer 18

PAPP-A IS A GLYCOPROTEIN SECRETED BY THE PLACENTA AND DECIDUA

Question 19

HOW ML OF FLUID IN THE NUCHAL FOLD IS ASSOCIATED WITH TRISOMY 21

Answer 19

MORE THAN 3 MM OF FLUID

Question 20

DOES ACOG RECOMMENDED CELL FREE FETAL DNA TESTING TO LOW RISK WOMEN IF SO WHY AND WHY NOT

Answer 20

THE PPV VALUE IS OF CONCERN, THEREFORE THE ACOG DOES NOT RECOMMEND TESTING WOMEN WITH LOW RISK FACTORS

Question 21

What is expanded carrier testing?

Answer 21

Expanded carrier testing is an approach that can identify a greater number of diseases, and is applied across all ethnic groups, regardless of risk status.