Premidterm Vitamins/cofactors And Shit

Question 0

Copper

Answer 0

Needed for:
Lysyl oxidase (ECM)-(hydroxy)lysine to al(hydroxy)lysine of collagen for covalent cross linking.
Complex 4/cytochrome oxidase

Question 1

Vitamin C

Answer 1

Cofactor for prolyl hydroxylase and lysyl hydroxylase (modify prepro-alpha chains of collagen). Deficiency causes scurvy.

Question 4

B12

Answer 4

Needs intrinsic factor from parietal cell for proper absorption, otherwise pernicious anemia

Question 5

B3

Answer 5

Niacin

Used to make NAD+

Question 6

B2

Answer 6

Riboflavin

Used to make FAD

Question 7

Thiamine

Answer 7

TPP
Aka B1
Used in PDH, aKgDH, branched chain fatty acid dehydrogenase, transketolase
Deficiency: Werner-korsakoff syndrome
(Alcoholics) down ATP, increased cardiac output(wet beri-beri) ataxia, cerebral hemorrhage

Question 8

Lipoic Acid

Answer 8

PDH, aKgDH, branched chain fatty acid dehydrogenase

Effected by arsenic poisoning (E2)

Question 9

PLP

Answer 9

Required by glycogen phosphorylase

B6

Question 10

B7

Answer 10

Biotin

Used in pyruvate carboxylase