premedication Flashcards

1
Q

What are the available anti sialogogues?

A

Atropine, scopalamine and glycopyrolate

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2
Q

What is the difference in structure in antisialogogues?

A

Atropine and scopaliamin are tertiary amines and cross the BBB
Gycopyrrolate has quaternary structure (synthetic) and does not cross BBB

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3
Q

Which is the most potent anti sialoguogu?

A

Scopalamine, but it is also most sedative. (3x as potent as atropine)

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4
Q

What is dose of glyco IM?

A

0.2 mg. More potent antisialogogue effect than IV. .0.2X more potent than atropine

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5
Q

wht is onset and duration of atropine and glyco?

A

Atropine 1-2 min
glyco 2-3
both last 30-60 min

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6
Q

How are anticholinergics cleared?

A

All cleared by kidneys. Renal failure is not a contraindication. glyco has fastest clearance

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7
Q

What procedures benefit from anti sialogogue?

A

FFOB, endoscopy, ENT cases

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8
Q

What anti sialogogue should be admistered in POHA prior to FFOB?

A

Glyco-IM-0.2-0.4

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