Prelim-Endterm Flashcards
A greek philosopher in 4000 B.C theorize that all matter is made of both indivisible and invisible particles “atoms.”
Democritus
west turkey discovered “loadstones.” Used for navigation religiory and magical purpose.
Magnesia
in 1819 discovered that electricity produces magnetism.
Hans christian oersted
1831 twelve years after the discovery of oersted discovered electricity.
Michael faraday
made the heart of MRI mathematics “Fourier transform.”
Jean-Baptiste-Joseph Fourier
1860 discovered magnetic lines of force could be mathematically expressed. Electrical and magnetic fields coexist at a 90-degree angle.
Sir James clerk Maxwell of Scotland
1868 discovered invisible electromagnetic waves exist with varying frequencies.
Heinrich hertz of Germany
discovered rotating magnetic field.
Nikola Tesla
First described and measured in molecular beams on magnetic resonance, Rabi method involved using electromagnetic of approximately 0.21 and a hairpin coil producing an oscillatory RF-field of about 3.5 MHz. The RF-field was maintained at a constant frequency and the main magnetic field was varied by changing its current. Rabi then passed a “molecular beam” of lithium chloride (LiCi) molecules through a vacuum chamber and subsequently into the magnetic apparatus in 1938 he and his team reported energy absorption/resonance peak for both Li and Ci as predicted. Rabi named this phenomenon “nuclear magnetic resonance”.
Isidor Isaac Rabi
their development of new ways and methods for nuclear magnetic precision measurements, expanded the technique for use on liquids and solids in NMR, for which they shared the Nobel prize 1952.
Felix Bloch and Edward Purcell
physician/physicist July 3, 1977, performed the 1st MRI whole body transaxial proton density weighted slice image. It took 4 hrs and 45 mins for the 1st scan, father of MRI (Magnetic Resonance Imaging), indomitable name of Damadian’s whole body scanner.
Dr. Raymond Damadian
demonstration of use of magnetic gradients for spatial localization and actual demonstration of 1-D imaging (1D MR image) which lead to the experiments of…
1952
designed the gradient coils, developed a way to generate the 1st MRI image in 2D and 3D, using gradients
Dr. Paul Lauterbur
from university of Nottingham then developed a mathematical technique that would allow scans to take seconds rather than hours and produce clearer images than Lauterbur had.
Peter Mansfield-
Owing to __ a mathematical technique called a __ could then be used to recover the desired image greatly speeding up the image process
Larmor precession, Fourier transformation
selective excitation or sensitization of tomographic image slice was invented by sir Peter Mansfield’s group.
1974
Richard ernst’s group invented the two dimensional Fourier transformation.
1975
Clow and Young produced the 1st published image of human head.
1978
General electric introduced high field 1.5 tesla systems
1984
for their discoveries concerning magnetic resonance imaging Paul Lauterbur and Sir Peter Mansfield were awarded the Nobel prize for medicine & physiology.
2003
a magnet whose magnetic field originates from permanently ferromagnetic materials (permanent magnet) to generate a magnetic field between two poles of magnet. There is no requirement for additional electrical power or cooling, and the iron-core structure of the magnet leads to a limited fringe field and no missile effect. Due to weight considerations __ magnets are usually limited to maximum field strength of 0.3-.5T
Permanent magnet
A type of magnet that utilizes the principle of electromagnetism to generate magnetic field. Typically large current values and significant cooling of the magnet coil is required. The resistive magnets does not require cryogens but needs a constant power supply to maintain a homogenous magnetic field and can be quite expensive to maintain. Resistive magnets fall into two general categories- iron core and air core.
Electromagnets or resistive system
Magnets that are partially built from superconducting materials and therefore reach much higher magnetic field intensity. Coil windings of superconducting magnets are made of wires of a type 2 superconductor. Liquid helium (-459F,0 K -273C) is commonly used as a coolant, which consequently conclude refilling. There are cryogen-free superconducting magnets with a closed-cycle refrigerating system at horizon. Superconducting magnets typically exhibits field strengths of greater than 0.5T, operate Clinically up to 3T and have a horizontal field orientation which makes them prone to missile effects without significant magnetic shielding.
Superconducting magnet
4-7 tesla
Ultrahigh field
1.5-3 tesla
High field
0.5-1.4 tesla
Mid field
0.2-0.4
Low field
<0.2 tesla
Ultra low field
Substance having no unpaired orbital electrons weakly repelled by either magnetic poles Ex: water and plastic
Diamagnetic
Materials lie somewhere between ferromagnetic and non-magnetic
Paramagnetic
Strongly magnetized by a magnetic and usually can be permanently magnetized by exposure to a magneticfield Ex: ALNICO (aluminum, nickel, cobalt)
Ferromagnetic
An atom is composed of?
Nucleus and revolving electron
The nucleus is composed of?
Protons and neutrons
Atoms with odd numbers of protons in their nuclei exhibits the property of?
Magnetic resonance
Has a single proton and thereby a large magnetic moment, also abundantly present in the body in the form of water and fat therefore, it produces the best magnetic resonance signals
Hydrogen
Therefore used in magnetic resonance imaging
Hydrogen ions
Is a vector quantity consisting of both a north and south pole
Magnetic field
A magnetic field characterized by its own magnetic north and south poles separated by a finite distance
Magnetic dipole
Refers to spinning motion of positive protons and the negative electrons that create a small magnetic field about the atom.
Magnetic moment
The amount of magnetic flux in a unit area perpendicular to the direction of magnetic flow
Magnetic intensity
A device that attracts iron and produces a magnetic field, the biggest and most important part of MRI system
Magnet
Precess or tumble
Spin
The phenomenon of magnetic field spinning or gyrating around imaginary axis of its own creation
Precession
Is the rate at which the nuclei complete a revolution about the precession path (megahertz or millions of cycle per second)
Frequency precession
Ratio between magnetic moment and angular momentum (disintegration constant in nucmed)
Gyromagnetic ratio
Angle formed between a precessing object and its imaginary axis
Angular momentum
Refers to that portion of the electromagnetic spectrum in which electromagnetic waves can be generated by alternating current to an antenna
Radiofrequency pulse
Specific frequency of resonance. Is located based on the particular tissue and strength of the main magnetic field
Larmor frequency
Phenomenon resulting in the absorption or emission of electromagnetic energy by nuclei or electrons in a static magnetic field, after exitation by a suitable magnetic field
Resonance
Time usually in fraction of a second in w/c the hydrogen nuclei switches from a magnetized state go a demagnetized state when magnetic pulse is turned off
Relaxation time
A biological parameter that is used in MRI to distinguish between tissue types, is a measure of the time raken to realign with the external
T1 relaxation time/spin lattice/longtudinal relaxation
Time required for a component of net magnetization vector to return __of its original value following an exitation pulse
T1 relaxation time, 63%
In the rotating frame, the net magnetization vector decays as spins lose phase coherence and begin to cancel each other out, they do this because they experience slightly different magnetic field strength due to interaction between spins, this cause some spin to “lag behind” the average and some “get ahead” of the average.
Free induction decay
Time required for a component of net magnetization vector to return __ of its orginal value following exitation pulse is?
T2 relaxation time, 37%
Interaction between individual spins
T2 relaxation time/spin-spin relaxation/transverse relaxation
Interaction between spins and bo inhomogeneity
T2*/t-two-star
Time between middle of exciting
TE/echo delay time/time echo
Period of time between the beginning of a pulse sequence and the beginning of the succeeding (esentially identical) pulse sequence
TR/repetition time
When an MRI is set to produce a PDWI image, the tissue with higher concentration or density of protons (hydrogen atoms) which produce the strongest signal and appears brightest on the image, produces contrast mainly by minimizing the impact of T1 and T2 differences with long TR (2000-5000ms) and short TR (10-20)
Proton density
Very useful for brain imaging (because of great white matter matter gray contrast), useful for extremity imaging (ankle, knee, elbow, shoulder, and hips), can be useful in thighs, lower legs, upper arm and forearm imaging, very useful for temporomandibular joint imaging.
PDWI (proton density weighted image)
Tr and te for T1W
short, short
Tr and te for T2W
long, long
Tr and te for PDW
Long, short
In clinical practice: TE is always shorter than?
TR
A short TR = value approximately equal to the average?
T1 value usually lower than 500 ms
A long TR = 3 time the?
Short TR, usually greater than 1500 ms
A short TE is usually lower than?
30 ms
A long TE = 3 times the short TE, usually greater than?
90 ms
is referred to as the longitudinal magnetization.
MZ
There is no (if it returns to normal equilibrium or relax that is T1)
transverse (Mxy) magnetization
__ referred to as __(if it returns to normal equilibrium or relax that is T2)
Mxy, transverse magnetization
Structures in short T1 (bright appearance)
Fats, proteinogenous fluids, subcutaneous blood
Structures in LONG T1 (dark appearance)
Neoplasm, Edema, inflammation, Pure fluid, CSF
Structure in short T2 (dark appearance)
Blood breakdown products
Structures in LONG T2 (bright appearance)
Neoplasm, Edema, Pure Fluid, CSF
Different in PWDI: Bone marrow (fatty marrow is usually __)
equal to or higher than that of muscle, (bright)
Different in PWDI: Fat (__ than the fat signal in T1 images)
bright (slightly darker)
Diffrent in PWDI: Fluids (__ than the fluid signal in T2 images)
bright (darker)
Diffrent in PWDI: White matter
darker than bright gray
Diffrent in PWDI: Gray matter
bright gray
Diffrent in PWDI: Moving blood
dark
Diffrent in PWDI: Muscles
gray
Diffrent in PWDI: Bone
dark
Diffrent in PWDI: Air
dark
optimum signal intensity
Hyperintense
weak signal intensity
Hypointense
same signal intensity
Isointense