Pregnancy Complications & Warning Signs for Providers Flashcards
1st Trimester bleeding
- Bleeding in first 12wk of pregnancy
- 20-40% of women have this (90% w/FHT will progress to term)
- 80% of SAB occur in 1st Tri
- Any bleeding deserves attn.
1st Trimester bleeding Differential Dx
- Threatened/Spontaneous abortion
- Ectopic pregnancy
- Cervical abnormality: cervicitis, cervical polyps
- Vaginitis
- Trauma
- Disappearing twin
- Subchorionic hemorrhage (most common abnormality on US w/viable embryo and bleeding)
B-HCG
- 8-9d after fertilization
- Doubles q48-72hr with normal IUP
- Increases only by 1/3 if ectopic
- Rule of 10:
- 100 @ 1st missed period
- 100K @ 10wk
- 10K @ term
Spontaneous Abortion
- SAB: occurs w/out cause
- Threatened AB: S/S of possible loss (bleeding with or without pain)
- Inevitable AB: Cervix is dilating
- Incomplete AB: Parts of products are retained
- Complete AB: all products are expelled
- Missed AB: Fetus died before 20wk but products retained for 2+wk
- Recurrent/Habitual AB: 3+ consecutive 1st Tri miscarriages
Management of SAB
- Blood type: RhoGam for Rh-Negative women
- Baseline B-HCG in 48hr
- US: See IUP on ABD US @B-hCG 6500; On Transvaginal US @B-hCG 2000
- Inevitable or incomplete: D&C; observant mgmt.
- GC/Chlamydia test/Wet Prep
Ectopic Pregnancy
- Implantation of blastocyte anywhere but uterus
- 2nd leading cause of maternal death in US
- 1:85 pregnancies; higher in 35+yo
- Causes: STD (GC, chlamydia), salpingitis, failed BTL
- S/S: Amenorrhea, spotting, unilateral lower ABD/Pelvic/adnexal pain; may be asymtomatic; severe vaginal pain with/without bleeding
Ectopic Pregnancy: PE
- Severe ABD pain
- Missed period
- Free fluid of US
- Vaginal bleeding
- Mild S/S of pregnancy
- Asymptomatic, until tube ruptures
- Cul-de-sac fullness
- Shoulder pain r/t diaphragmatic irritation
- Vertigo, syncope
Ectopic Pregnancy: Dx
- B-hCG >1500 but no IU gestatonal sac
- @5 wk gestational sac visible on TV US
- hCG never >6500 before tubal rupture
Ectopic: Tx
- refer to OB/GYN
- methotrexate
- salpingectomy/tubal resection
- RhoGam if indicated
Hydatiform Mole S/S
- Abnormal bleeding
- Size > dates frequency
- Lack of fetal activity and FHR
- Hyperemesis
- Gestational HTN before 20wk
Hydatiform Mole Dx
- Ultrasound
- bHCG
- Not officially made until after tissue removed
Hydatiform Mole Mgmt.
- Uterine evac by suction curettage
- CMP, CBC, LFT, Thyroid function
- Monitor for malignant changes
- Avoid pregnancy for 1yr
- Serial b-hCG q2wk until normal, then q month for 6mo, then q 2month for 1 yr
Molar Pregnancy (Gestational trophoblastic Dz) types
- Complete/partial molar pregnancy (benign)
- Invasive molar pregnany: Goes through uterine wall but does not migrate
- Choriocarcinoma (malignant)
Molar pregnancy cause
- Caused by father’s genes NOT mother’s
Questions to ask about 1st Trimester bleeding
1) Has pregnancy been confirmed
2) Once confirmed, is this bleeding as heavy as a normal period?
3) Heavy? (6+pads/12hr)
- Heavy bldg + passing tissue + cramping? think SAB
- Heavy bldg. with no pain? Think molar
- Light bleeding + Pain? consinder ectopic
- Light bleeding + no pain = think AB or implantation
4) Abnormal pain or cramping? consider ectopic or SAB