Pregnancy & Birth Flashcards
Define Ejaculation
when the contents of the ducts and glands are propelled into the urethra then out of the body
What is in the ejaculated material and what reactions accompanies an ejaculation?
The ejaculated material consists of fluid/semen which contains sperm. Accompanying the ejaculation is a rapid heartbeat, an increase in blood pressure and breathing rate, and intensely pleasurable sensations. This is referred to as an orgasm
Define Insemination
The process where the sperm are released into the vagina
Where and how does the sperm travel after it is within the vagina?
Once within the vagina, the sperm travel through the cervix and uterus, into the uterine tubes.
- This occurs very quickly
- Muscular contractions of the uterus
What is sperm mortality?
Sperm mortality is the death rate of sperm. Of the hundreds of millions of sperm deposited into the vagina, only a few thousand reach the uterine tubes, one reason why a large number of sperm are required for fertilsation to occur
Define Fertilisation + where it occurs
Fertilisation is the fusion of a sperm and egg, and occurs in the uterine tubes when the egg is one third of the way down the tube.
The two layers that surround the mature egg (secondary oocyte):
- CORONA RADIATA consists of follicular cells held together by an acid.
- ZONA PELLUCIDA a glycoprotein matrix surrounding the plasma membrane of the oocyte
How does the sperm break through the corona radiata and zona pellucida?
- The acrosome on head of the sperm contain an enzyme that breaks down the acid. The many sperm work together to break down the corona radiata.
- When the acrosome meets the zona pellucida, the ACROSOMAL REACTION occurs, causing digestive enzymes to be released that break down the glycoprotein matrix
What occurs once the sperm enters the egg?
- The formation of the fertilisation membrane is stimulated, preventing entrance of any more sperm
- the entrance of the sperm stimulates the secondary oocyte to complete the second meiotic division
- Sperm’s tail is absorbed and head begins to move through the cytoplasm in the form of a MALE PRONUCLEUS.
- nucleus of the egg develops into the FEMALE PRONUCLEUS which fuses with the male pronucleus to form a single nucleus with the diploid number of chromosomes.
Cleavage
The process by which a zygote repeatedly divides by MITOSIS.
What is a morula + where does it travel
A solid, spherical mass of cells formed after 3 days of cleavage. Travels down fallopina tube into uterus.
What is a blastocyst?
- Between days 4-6, the morula further divides into a BLASTOCYST
- The blastocyst is a hollow ball of cells with fluid in the middle and a mass of ~30 stem cells at one side of the cavity called the INNER CELL MASS
- The outer layer of cells of the blastocyst are known as TROPHOBLASTS and eventually become part of the placenta
- The inner cell mass will develop into the EMBRYO
What is implantation?
- When the blastocyst sinks into the soft endometrium to become firmly attached to the wall of the uterus.
- Occurs around day 7 and enables the blastocyst to gain nourishment for growth
3 primary germ layers
ECTODERM: Outermost layer of cells – will give rise to the body’s outermost layers of skin, central and peripheral nervous systems, eyes, inner ears.
MESODERM: Middle layer of cells – heart and a primitive circulatory system, bones, muscles, kidneys, much of the reproductive system, stomach and intestines
ENDODERM: Inner layer of cells – will become a simple tube lined with mucous membranes. The lungs, digestive tract lining and thyroid.
4 embryonic membranes and function
- Amnion
- Chorion
- Allantois
- Yolk sac
function is to provide embryo nourishment as it develops
What is the amnion?
- First membrane to develop
- secretes amniotic fluid
- cushions foetus, protecting it form injury
- maintains a constant temp
- allows foetus to move freely - developing joint and muscle movement
- as foetus grows, the amnion grows with it
- ruptures just before childbirth expelling amniotic fluid
What is the chorion
- surrounds embryo and other 3 embryonic membranes
- as amnion enlarges it fuses with outer layer of chorion
- Eventually chorion becomes the main part of the foetal portion of the placenta
What is the placenta + functions
- The placenta is a disc-like organ which grows over the surface of the uterus.
- The job of the placenta is to supply food and oxygen to the foetus and to remove wastes such as urea, uric acid, and ammonia.
- acts as an endocrine gland and so secretes a number of hormones necessary for maintaining pregnancy.
- Allows the transport of antibodies from mother to foetus, so foetus is immune to diseases mother is immune to.
- exchange of CO2 and O2
What are chorionic villi?
Finger-like projections that develop from the outer layer of cells of the early embryo;grow to form part of the placenta
Do foetal + maternal blood mix to exchange materials. If not then how do they exchange them?
- Foetal and maternal blood do not mix
- Exchange of materials takes place via diffusion and active transport