Preformulation And Solubility Flashcards
What is solubility in quantitative terms?
The concentration of solute in a saturated solution at a certain temperature (in g/mL)
Quantitative solubility provides a measurable value that indicates how much solute can dissolve in a solvent under specific conditions.
How is solubility defined in qualitative terms?
The mixture of two or more components that form a homogenous phase
Qualitative solubility focuses on the nature of the mixture rather than specific numerical values.
What is solubilization?
The preparation of a thermodynamically stable solution of a substance, which is normally insoluble or very slightly soluble, in a given solvent by the introduction of an additional component
Solubilization is crucial for making substances that are typically hard to dissolve more readily available in solution.