Preeclampsia Flashcards

1
Q

Early onset preeclampsia is dx prior to how many week?

A

34;

Late onset is dx after 34 weeks

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2
Q

In normal placental development, maternal spinal arteries convert high-resistance and narrow muscular vessels to what?

A

Low-resistance, high-capacity vessels

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3
Q

In women who develop preeclampsia, what happens to the maternal spiral arteries?

A

They remain small, narrow, with high-resistance; which leads to under-perfusion of the placental-fetal unit

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4
Q

Which chronic and obstetrical conditions increase risk of abnormal placentation and preeclampsia?

A
  1. Chronic hypertension
  2. Diabetes
  3. Lupus (SLE)
  4. Chronic Kidney Disease (CKD)
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5
Q

What are five results of capillaries leaking?

A
  1. Proteinuria
  2. Facial edema
  3. Pulmonary edema
  4. Ascites
  5. Pleural effusion (build up of excess fluid on the pleura outside the lungs)
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6
Q

What are four sx of Preeclampsia?

A
  1. Epigastric pain
  2. CNS
  3. Bleeding
  4. Nausea/vomiting
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7
Q

What are the three ranges of BP?

A
  1. Normal
  2. Mild
  3. Severe
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8
Q

What are four results of Fibrinolysis and Hemolysis?

A
  1. HELLP
  2. Renal failure
  3. DIC
  4. Low platelets; High Liver enzymes
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9
Q

Is the degree of end-organ involvement correlated with the degree of hypertension?

A

no

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10
Q

What are the consequences of sustained/severe restriction of placental blood flow to the placental-fetal unit?

A
  1. IUGR

2. Oligohydramnios

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11
Q

Is proteinuria required to dx Preeclampsia?

A

No

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12
Q

What Creatinine level indicates severe disease?

A

1.1mg/dl or doubles from baseline.

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