Preeclampsia Flashcards
Early onset preeclampsia is dx prior to how many week?
34;
Late onset is dx after 34 weeks
In normal placental development, maternal spinal arteries convert high-resistance and narrow muscular vessels to what?
Low-resistance, high-capacity vessels
In women who develop preeclampsia, what happens to the maternal spiral arteries?
They remain small, narrow, with high-resistance; which leads to under-perfusion of the placental-fetal unit
Which chronic and obstetrical conditions increase risk of abnormal placentation and preeclampsia?
- Chronic hypertension
- Diabetes
- Lupus (SLE)
- Chronic Kidney Disease (CKD)
What are five results of capillaries leaking?
- Proteinuria
- Facial edema
- Pulmonary edema
- Ascites
- Pleural effusion (build up of excess fluid on the pleura outside the lungs)
What are four sx of Preeclampsia?
- Epigastric pain
- CNS
- Bleeding
- Nausea/vomiting
What are the three ranges of BP?
- Normal
- Mild
- Severe
What are four results of Fibrinolysis and Hemolysis?
- HELLP
- Renal failure
- DIC
- Low platelets; High Liver enzymes
Is the degree of end-organ involvement correlated with the degree of hypertension?
no
What are the consequences of sustained/severe restriction of placental blood flow to the placental-fetal unit?
- IUGR
2. Oligohydramnios
Is proteinuria required to dx Preeclampsia?
No
What Creatinine level indicates severe disease?
1.1mg/dl or doubles from baseline.