Pre-Test (Skin and friends, Trauma, Transplant/Immunology/Oncology) Flashcards
Nerve that innervates most of the intrinsic muscles of the hand
Ulnar nerve
Nerve involved with extension of wrist
Radial
Margins of excisions for melanoma
4 mm- 3 cm margin
Frostbite tx
Rapidly warming by immersion in water slightly above normal body temp (40-44 c)
Another name for SCC form chronic skin wound
Marjolin ulcer
Silver nitrate AE
Hyponatremia and hypokalemia
Silver sulfa AE
Neutropenia
Most common malignant tumor of the lip
SCC (esp lower)
What do composite tissue grafts contain
Tissue in addition to dermis/epidermis
How long should a clean would be present before it should no longer be closed
6 hours
Tx for a trauma pt with a seatbelt sign
Worried for enteric or mesenteric injury, the patient should be held and observed regardless of test results
Surgical treatment of choice for a ruptured vein in an unstable patient
Ligation, rather than repair
CT scan sensitivity for penetrating abdominal trauma
Low, good for blunt abdominal trauma
Insulin levels after acute trauma? BS levels?
Shot drop in insulin followed by a significant rise
Still hyperglycemia due to elevated insulin resistance
Best surgery for common bile duct transection in stable patient? Unstable?
Stable: Roux-en-Y choledochojejunostomy
Unstable: T tube placement
Absolute indications for surgical neck exploration
Acute signs of airway distress (stridor, hoarseness, dysphonia)
Visceral injury (sub-q air, dysphagia, hemoptysis)
Hemorrhage
Neuro signs referable to carotid injury (stroke, AMS)
Duodenal obstruction following BAT likely? Management?
Likely a duodenal hematoma
Mgt conservative: NG tube and observation
Blunt carotid artery injuries should be treated with?
Full systemic anticoagulation in the absence to any contraindications to prevent stroke
Cushing triad in inc ICP
Hypertension
Bradycardia
Irregular respirations
What nerve innervates most of the flexors of the hand? What else does it get
Medinan nerve, also gets pronator muscles of forearm and lots of hand sensation
Two good ionotropes for cariogenic shock
Dobutamine and Dopamine
Why are popliteal artery injuries associated with knee dislocations?
Extreme force required to dislocate the joint
Nitrogen balance in sepsis
Negative, due to breakdown and increased urinary loss
What should be requested for suspected colonic perf?
CT abdomen
When is surgery indicated in orbital trauma
Enopthalmos greater than 2mm
Diplopia on primary or inferior gaze
Entrapment of EOM
Fracture greater than 50% of orbital floor
What happens to the Lactate in LR solutions
Metabolized to HCO3 in the liver –> helps correct metabolic acidosis
Mgmt of low grade renal injuries
Strict bed rest for 24-72 hours with serial Hgb levels
Tx for injury of major pancreatic duct to left left of the mesenteric vessels
Distal prancreatectomy
In absence of sepsis, management of patients with enterocutaneous fistulas
Bowel rest, TPN, and correction of electrolyte abnormalities
initial management of extraperitoneal bladder injuries
Initial catheter drainage followed by repeat imaging to confirm healing
Pos DPL criteria
10cc gross blood
> than 100,000 ul RBC
> 500 uL WBC
Elevated amylase, bili, or alk phos
First step in treating neurogenic shock? Then?
Restore volume (Normal CP is 2-6) Then vasoconstrictors
Ideal tx of pericardial tamponade from trauma
Pericardiocentesis under local anesthesia in the OR (that way able to surgically explore after)
Guidelines for thoracotomy in hemothorax patients
> 1500 mL of immediate drainage or >200 mL/h for several hours after
Pulmonary contusion def
hemorrhage and edema of the lung parenchyma without parenchymal disruption
Initial tx of open tension pneumothorax
Place occlusive dressing over the defect
What makes TNF
Monocytes/macrophages
Chronic liver transplant rejection characterized by
Paucity of bile ducts on biopsy due to immune-mediated injury to biliary epithelium
What is the cross match done before transplant
Donor lymphocytes with recipient serum and compliments
Tumor lysis syndrome is mediated by?
Cytotoxic T cells
Cyclosporin inhibits?
IL-2
Acute kidney rejection mgmt
Renal biopsy, steroid boost, and immunoglobulin therapy
Most common post transplant infections
Viral (CMV, EBV, HSV, VSV)
Best drug for severe acute rejection that does not respond to steroid tx
Muromonab-CD3
Wilms tumor ass w/
Aniridia, GU abnormalities, MR
Tx for early stage seminoma
Orchiectomy and external beam radiation
Who should get sentinel node biopsies in breast Ca
Pt’s who do not have clinically positive lymph node disease
How are cardiac allografts matched
Only by size and ABO type
GIST drug
Imatinib (TKI)
Mammogram rec for BRCA1 carriers
Once every 6 months (biannual) starting at age 25
BRCA1 vs BRCA2
BRCA1: likely ER neg, colon and prostate ca in males
BRCA2: likely ER+, also GI cancers
Post transplant lymphoproliferative disorder ass w/?
EBV
What is tertiary hyperparathyroidism? Tx?
Persistant hypercalcemia 2/2 autonomous parathyroid function after renal transplant
Tx: total parathyroidectomy
Neg margin for colon cancer should be
5cm
Azothioprine AE
Bone marrow suppression