Pre-term labour Flashcards
What is prematurity?
Birth before 37+0
What is extreme prematurity?
<28 weeks
What is severe prematurity?
28-31+6
What is moderate prematurity?
32-33+6
What is late pre-term?
34-36+6
What is the age of viability?
24 weeks, but if 23+ and 400g, showing signs of life then resus often attempted
What is the incidence?
more than 52,000 in 2012
What is the major long term concequence of prematurity?
neurodevelopmental delay
What are the 4 types of risk factors for Preterm labour and PPROM?
- behavioural and environmental
- demographic
- Medical
- Reproductive
what are the 9 behavioural and environmental risk factors of pre term labour and PPROM?
- smoking
- drugs
- nutrition
- bmi
- physically demanding work (more likely to have injury + abruption)
- prolonged periods of standing / shift work
- domestic violence/abuse
- abdo injury
- stress - release of catecholamines can lead to premature labour
What demographic are more likely to go into preterm labour and PPROM? 4
- low socioeconomic status
- <17 y/o or >35 y/o
- ethnicity- from underdeveloped countries
What medical risk factors can cause preterm labour and PPROM? 7
Infection (Uti’s)
Diabetes - altered insulin requirement affects placental efficiency
Renal disease
Cardiovascular disease
Hypertension (delivery is only way to reduce)
Antiphospholipid syndrome - can lead to iugr
Psychiatric disorders
What are the reproductive risk factors? 9
- PPROM 2% of all pregnancies- 80% will then deliver
- placental abruption/pph
- inadequate antenatal care- low socioeconomic status/extreme lifetstyles
- multiple pregnancy - uterus stops growing, mcmca twins delivered early to prevent twin-twin transfusion
- cx abnormalities
- uterine abnormalities
- polyhydramnios
- IUGR
- history of preterm labour
What are the 5 ways to prevent pre-term labour?
- encourage healthy lifestyle
- comprehensive antenatal care
- ongoing risk assessment
- infection screening
- routine msu testing for UTI’s
How do we diagnose preterm labour?
- measurement of cervical length (<15mm high chance)
- fetal fibronectin
What 4 drugs are given in pre-term labour?
Antenatal corticosteroids - beta/dexamethasone
Nifidipine
Magnesium sulfate
Antibiotics
What are corticosteroids for?
26-34/40, makes baby stressed so they produce surfactant to keep lungs inflated