Pre-term Labour Flashcards

1
Q

define term

A

37 to 42 weeks

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2
Q

define EDD

A

40 wks

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3
Q

define pre term

A

<37 wks

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4
Q

what % births are preterm

A

8

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5
Q

what % of preterm births are elective

A

25

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6
Q

reasons for intentionally delivering someone preterm

A

PET
IUGR

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7
Q

define labour

A

regular contractions of uterus resulting in changes of cervix

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8
Q

define extreme pre term

A

<28 wks

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9
Q

define very preterm

A

28-32 wks

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10
Q

define late to moderate preterm

A

32 to 37 wks

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11
Q

when does all morbidity fall in terms of wks of gestation

A

32 weeks onwards

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12
Q

preterm labour Ix

A

Hx
speculum / bimanual
USS
TVUSS - cervical lengthening
CTG (contractions)

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13
Q

preterm labour RFs

A

prev preterm
twins
genital tract infections
PPROM
uterus issues - eg bicornate
cervix issues - eg LLETZ
placental issues
smoking, stress

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14
Q

Sx of preterm labour

A

dull backache
abdo tightenings
lower abdo pressure
PVB or spotting
PROM - gush or trickle

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15
Q

when should preterm labour be Tx (wks)

A

<29+6 wks
or >30 wks

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16
Q

why is TVUS done in preterm labour

A

determine cervical length - very hard

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17
Q

what is foetal fibronectin used for

A

to rule out preterm labour if its negative

18
Q

what does a positive foetal fibronectin indicate

A

nothing, can be false positive

19
Q

what causes a false positive of foetal fibronectin

A

sex
ROM
PVB

20
Q

what does a negative foetal fibronectin indicate

A

unlikely to start labour in 14 days

21
Q

what % of term vs preterm births have PPROM

A

3% term 30-40% preterm

22
Q

complications associated with PPROM

A

neonatal sepsis
cord prolapse
lung hypoplasia

23
Q

what is the average time from PPROM to birth

24
Q

Ix for PPROM

A

speculum - look for fluid
USS estimation of amniotic fluid if neg

25
what result is diagnostic for PPROM
squirt of fluid out of cervix upon coughing in speculum exam
26
Mx of PPROM inc specific drug, dose, freq & when to stop
oral ABx prophylaxis - erythromycin 250mg 4x daily until labour or 10 day course
27
what ABx should not be given for PPROM prophylaxis and why
co-amoxiclav - increased NEC risk
28
what condition is there a risk of with PPROM & how is this monitored for
chorioamnionitis CRP or temp
29
when should steroids be given in PPROM
24 to 34 weeks
30
when should tocolytics be considered for PPROM
benefit of maternal steroids
31
when should tocolytics NOT be used in PPROM
foetal distress APH PET
32
types of tocolytics indicated in PPROM
nifedipine (CCB) atosiban (oxytocin antagonist)
33
which steroids are given in PPROM
betamethasone or dexamethasone
34
why are betamethasone / dexamethasone used in PPROM vs other steroids
cross placenta no mineralocorticoid effect
35
dose / route / freq of steroids in PPROM ?
12mg IM x2, 12 or 24 hours apart then again after 2-7days
36
purpose of MgSO4 in preterm labour
neuroprotective for preterm babies
37
dose of MgSO4 for preterm labour
4g IV bolus over 15 mins
38
for what is vaginal progesterone / cervical cerclage offered
preterm labour 2nd trimester miscarriage cervical length <25mm in wks 16-24
39
how does progesterone affect pregnancy
maintains the pregnancy through uterine quiescence
40
when is cervical cerclage done
12 to 14 wks rescue clerage done 23 wks
41
what is cervical cerclage
stitching up cervix to narrow cervical os
42
when is cervical cerclage removed
37 weeks