Pre/Post Op Flashcards
when does DVT MC occur post-op
days 3-5
positive Homan sign
pain to the calf with dorsiflexion of foot
dorsiflexion
the action of raising the foot upwards towards the shin
if you think someone may have a DVT what screening modality FIRST
LE Doppler US
If there is low probability –> D Dimer first; if positive then US
most commonly used prophylactic measures for DVT before surgery
anticoagulation therapy such as low-dose unfractionated heparin 2 hours before surgery and every 8 to 12 hours after surgery until the patient is mobile along with intermittent pneumatic compression
pts should be mobile ASAP
What risk factors make up the Virchow triad?
Venous stasis, endothelial damage, and hypercoagulability
what veins are MC affected by DVT in LE
superficial femoral and popliteal veins in the thigh
the peroneal and posterior tibial veins
Examples of causes of vascular endothelial injury from virchows triad
surgery (total hip replacement), central venous catheterization, and trauma. In upper extremity DVT, endothelial injury due to central venous catheter, pacemaker, or injection drug use is the major causative factor
for what D Dimer level should an US be ordered
greater than 500 mg/L
definitive dx DVT
venography, but it is associated with increased risks and is rarely used in the clinical setting
study of choice for diagnosing PE
CT angiography
what do you use to diagnose PE if CT angiography is unavailable or contraindicated
ventilation-perfusion lung scan
What is phlegmasia alba dolens?
A rare complication of deep vein thrombosis (DVT) in pregnancy where the leg turns milky white
where does a pulmonary embolism arise from
often arises from thrombi in the systemic venous circulation or the right side of the heart but can also arise from invasive tumors in the venous circulation
what things cause a hyper coagulable state for virchows triad
autoimmune diseases, malignancy, use of oral contraceptives, pregnancy, genetic disorders such as factor V Leiden, and protein C or S deficiency
what things cause venous stasis for virchows triad
immobilization, chronic venous insufficiency, varicose vein, and paresis due to stroke
sx pulmonary embolism
sudden onset of dyspnea accompanied by pleuritic chest pain, apprehension, cough, hemoptysis, and diaphoresis
may have concomitant DVT
PE for pulmonary embolism
tachycardia
tachypnea
crackles
low grade fever
what D Dimer level can exclude a pulmonary embolism
< 500 ng/mL
what criteria score can rule out PE
well’s score
what will EKG show for PE
ECG shows sinus tachycardia and nonspecific ST-T findings. The classic S1Q3T3 (large S wave in lead I, Q wave in lead III, inverted T wave in lead III) that indicates cor pulmonale is seen in a minority of patients with pulmonary embolism
what will chest radiograph show for PE
nonspecific abnormalities such as Westermark sign (vascular cutoff sign) and Hampton hump (pleural-based wedge infarct), although they may also be normal
A normal chest X-ray in the presence of _______ is suspicious for pulmonary embolism
hypoxia
what will a ventilation-perfusion lung scan show for PE
perfusion defects with normal ventilation
what is the imaging test of choice for PE
CT pulmonary angiography
Pulmonary angiography is gold standard but not used commonly due to wide use of CT pulmonary angiography
what med is often given initially for PE tx
LMWH
when is Inferior vena cava filter used for tx of PE
used in hemodynamically stable patients who have failed or cannot tolerate anticoagulation
Patients who are at high risk for major bleeding events may be managed with
intermittent pneumatic compression or early ambulation, or, when chemical prophylaxis is used, very close monitoring for bleeding events
Wells Criteria for PE
signs and symptoms of deep vein thrombosis (3 points), PE is the most likely diagnosis (3 points), heart rate > 100 bpm (1.5 points), immobilization ≥ 3 days or surgery in the previous 4 weeks (1.5 points), previous objectively diagnosed DVT or PE (1.5 points), hemoptysis (1 point), and malignancy with active treatment in the past 6 months or under palliative care (1 point)
wells score of 0-4
PE unlikely
this score + negative D dimer = rule out PE
wells score > 4
PE likely
further workup warranted
when should fibrinolytic therapy be administered for PE
Fibrinolytic therapy should only be administered in unstable patients who demonstrate refractory hypotension and who do not have contraindications to thrombolysis
What is the McGinn-White sign?
S1Q3T3 pattern on ECG associated with pulmonary embolism
Vitamin K-dependent clotting factors include
factors II, VII, IX and X
how is warfarin efficacy measured
prothrombin time or international normalized ratio (INR)
pt on warfarin: If the INR is greater than the goal but less than 5
skip the next dose
pt on warfarin: If the INR is 5–10 and the patient is not at risk of bleeding
skip the next 1-2 doses
you can administer vitamin K if they are about to undergo surgery
pt on warfarin: If the INR is > 10 and there is no bleeding or a low-moderate risk of bleeding
hold warfarin
administer vitamin K
pt on warfarin: life-threatening bleed
hold warfarin
administer vitamin K
administer fresh frozen plasma
are pts w DM more likely to become hyper or hypoglycemic after surgery
hyperglycemic - maybe due to stress?
how long should metformin be withheld before surgery
24 h
how long should sulfonylureas be withheld before surgery
48-72 h