Pre Midterm Content Flashcards
Content up to the midterm
True of false: ATP is a limited currency
true
True of false: anabolism is exergonic
false, anabolism is endergonic and catabolism is exergonic
The three types of biological work
mechanical, chemical, transport
do cells store more PCr or ATP
PCr.
Cells store about 4 to 6 times more PCr than ATP
Why do NADH and FADH2 provide energy molecules?
Because they have high energy-transfer potential
what is the respiratory (cytochrome) chain?
the final common pathway where electrons extracted from hydrogen pass to oxygen.
What is the last electron receiver in the electron transport chain?
Oxygen
Each mole of ATP formed from ADP conserves approximately how many kcals of energy?
7 kcals
True or false: Anaerobic glycolysis is fast and aerobic is slow
true.
the word for glycogen break down
glycogenolysis
the word for glycogen synthesis
glycogenesis
What is the name of the insulin dependent transporter in muscle fibers and adipocytes
GLUT 4
What does the Cori Cycle do?
Removes lactate released from active muscles and uses it to replenish glycogen reserves depleted from intense physical activity.
Each Acetyl-CoA entering the citric acid cycle release how many CO2 and how many pairs of H+?
2 CO2
4 Pairs of H+
What are the three components of aerobic metabolism?
Citric acid cycle, electron transport chain, Oxidative phosphorylation.
What is the body’s most plentiful source of energy?
stored fat
What are the two tasks of Free Fatty Acids (FFAs)?
- Re-esterify to form triacylglycerols
- Bind with intramuscular proteins and enter the mitochondria for energy metabolism by action of carnitine acyltransferase located on the inner mitochondrial membrane.
What is deamination and what is the main site where it happens
the removal of nitrogen from an amino acid. happens mainly in the liver.
Skeletal muscles contain enzymes that remove nitrogen from amino acids, what is this process called __________.
Transamination
What does it mean when an amino acid is glucogenic
It means that when it is deaminated it yields pyruvate.
What does it mean when an amino acid is ketogenic?
when deaminated, it yields acetoacetate (intermediate Acetyl-CoA)
What are the 5 conditions under which glycogen depletion can occur?
- Prolonged physical activity (eg. marathon)
- Consecutive days of intense training
- Inadequate energy intake (eg. routinely skipping meals)
- Dietary elimination of carbs (eg. keto)
- Diabetes, which impairs cellular glucose uptake
ATP last for how long?
1-2 sec
What are the three systems of energy provision pathways for ATP production? (chapter 7, p.162-169)
- Immediate energy system
- Short-term energy system
- Long-term energy system
What are the 4 “energy” sources fort he “synthesis” of ATP for muscular work?
- from the breakdown of PCr
- From the adenylate kinase (myokinase) reaction
- From the guanosine triphosphate reaction
- from food
What is the enzyme that catalyzes the breakdown of ATP?
ATPase
What catalyzes the breakdown of PCr?
Creatine kinase
In the Adenylate kinase reaction,
ADP + ADP –> ____________.
ADP + ADP –> ATP + AMP (adenosine monophosphate)
Immediate energy system is the primary energy source for what kind of exercise?
Acute
Strength, power, sprint
True or false?
Immediate energy stores have high rate of energy and high capacity.
False.
High energy rate but LOW capacity
what is the creatine protocol for loading?
approx. 20-30 g/day or 0.30 g/kg body mass/day of Cr over 3-5 days.
What is the creatine protocol for maintenance?
approx. 2-5 g/day or 0.03 g/kg/day for several weeks.
Why is creatine supplementation a bad idea for sports in which you need to make weight?
increased body mass due to retention of total body water.
What are the 3 classifications of carbohydrates?
Monosaccharides
Oligosaccharides
Polysaccharides
define monosaccharide. What are the 3 types?
basic unit of carbohydrate (glucose, fructose, galactose)
Define oligosaccharides, and state the 3 types.
2-10 monosaccharide molecule linkages (sucrose, lactose, maltose)
Define polysaccharide, name the two types.
3 to thousands of monosaccharide molecule linkages (starches and fibers)
What are the 4 main roles of carbs in the body?
- energy source during exercise at all intensities
- protein sparer - helps preserve tissue protein
- metabolic primer - for fat oxidation
- Fuel for CNS - primary fuel for nerve tissue
The body store _____Kcals of carbohydrates.
2000 kcals
muscle stores _____ g of glycogen.
400 g
liver stores ______g of glycogen.
90-100 g
What is the upper limit for glycogen storage on average?
15 g / kg of body weight
What are the 3 lipid groups
simple (triacylglycerols - saturated and unsaturated)
compound (phospholipids and lipoproteins)
derived (cholesterol)
The 4 major function of lipids are:
- energy source and reserve
- Protect vital organs
- thermal insulator
- vitamine carrier and hunger suppressor
True of false
fat serves as the main energy substrate during low intensity exercise.
True
Carbohydrates, primarily muscle glycogen, is the energy source during what intensity exercise
high intensity
Protein is constructed from ____________.
Linked amino acids
Carbohydrate depletion increase the use of fat or protein as a fuel?
Protein
The recommended amount of daily protein for both men and women is _______ g per Kg of body mass.
0.8 g / kg body mass
What are the two major functions of anaerobic (rapid) glycolysis / glycogenolysis?
- synthesis of ATP
2. generation of pyruvate
where does glycolysis / glycogenolysis take place?
sarcoplasm
The 3 stages of glycolysis are:
- the activation or priming stage
- The splitting stage
- Oxidizing and reducing stage