Pre-Eclampsia

Question 1

What is gestational HTN?

Answer 1

BP >140/90 mmHg that develops after 20 weeks EGA without history of HTN

Question 2

What is the definition of pre-eclampsia?

Answer 2

HTN + proteinuria (>300 mg/24 hr or urine P/Cr ratio > 0.3mg/dl)

or

HTN and one of:

1) PLT < 100
2) Liver transaminases 2x normal
3) Serum Cr. > 1.1 or 2x baseline
4) End organ dysfunction

Question 3

What is pre-eclampsia with severe features?

Answer 3

1) SBP >160 of DBP > 110
2) PLT < 100
3) Liver transaminases 2x normal
4) Serum Cr. > 1.1 or 2x baseline
5) End organ dysfunction

Question 4

What is eclampsia?

Answer 4

Pre-eclampsia + seizures

Question 5

What is HELLP?

Answer 5

Subset of pre-eclampsia defined by:

1) Hemolysis
2) Elevated liver enzymes
3) Low platelets

Question 6

Why is intubating pre-eclamptic patients more difficult?

Answer 6

Pregnant women already have edematous airways and pre-eclamptic patients have even more edematous airway

Question 7

How does magnesium affect sensitivity of non-depolarizing muscle relaxants?

Answer 7

Increases sensitivity

Question 8

Does magnesium affect sensitivity of succinylcholine?

Answer 8

No

Question 9

Normal therapeutic range from Mg2+?

Answer 9

4-6 meq/L

Question 10

At what Mg2+ level does prolonged PR, wide QRS occur?

Answer 10

5-10meq/L

Question 11

At what Mg2+ levels do deep tendon reflexes become depressed/absent?

Answer 11

> 10meq/L

Question 12

At what Mg2+ level is there SA/AV Node block and respiratory depression?

Answer 12

> 15meq/L

Question 13

At what Mg2+ level does cardiac arrest occur?

Answer 13

> 25 meq/L

Question 14

Does Mg2+ increase hypotension more in patients taking CCB’s?

Answer 14

No