Pre-Clinical Pharm Flashcards

1
Q

Propofol

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A

Diprivan

1.5-2.5 mg/kg adult
2.5-3.5 mg/kg peds
Decrease dose in elderly
PONV 10mg
Itching 10-15mg
Sedation 25-100 mcg/kg
TIVA 100-300 mcg/kg/min

GABAa agonist

3-5 minutes

Burns when injected
Decreases BP, SVR, CO. Cardiac sensitive. Bradycardia. Hypercapnia
Allergy. Hypoventilation. Apnea. Loss of airway reflexes. Myoclonus

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2
Q

Rocuronium

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A

Zemuron

0.6-1.2 mg/kg
Non depolarizing paralytic
Redose with 0.1mg/kg
Duration of 20-35 minutes
Does release histamine

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3
Q

Succ

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A

Anectine

-0.5-1 mg/kg
-Duration of 3-5 minutes
-Depolarizing Muscle Relaxant
-2 acetylcholine molecules bound together which attach to alpha subunits of nicotinic acetylcholine receptors and mimics depolarization.
-Releases Histamine
-increase K by 0.5mEq
-bradycardia from SA node action
-enhanced with anticholinesterase
-reversed with anticholinesterase
-upregulation of extrajunctional receptors
-increased intragastric pressure but also increase in LES pressure
-Dibucaine tests detects atpycal cholinesterase enzyme not the number
-slight increase in ICP

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4
Q

Vecuronium

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A

Norcuron
-non depolarizing parlaytic
-0.1 mg/kg
-duration of 20-35 minutes
-renal(20%) and liver excretion (80%)
-NO histamine release
-woman more sensitive than men

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5
Q

Cisatracurium

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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6
Q

Etomidate

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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7
Q

Lidocaine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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8
Q

Bupivicaine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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9
Q

Ropivicaine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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10
Q

LTA Kit

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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11
Q

Midazolam

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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12
Q

Fentanyl

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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13
Q

Neostigmine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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14
Q

Glycopyrolate

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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15
Q

Sugammadex

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
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16
Q

Dexmedetomidine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
17
Q

Ketamine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
18
Q

Atropine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
19
Q

Phenylephrine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
20
Q

Ephedrine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
21
Q

Vasopressin

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
22
Q

Famatodine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
23
Q

Norepinephrine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
24
Q

Clevidipine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
25
Q

Nicardipine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
26
Q

Labetalol

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
27
Q

Metoprolol

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
28
Q

esmolol

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
29
Q

protamine

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
30
Q

heparin

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A
31
Q

zofran

Trade Name
Dose
Mechanism of Action
Duration
Adverse Effects
Random facts

A