practicum 50 multiple choice Flashcards

1
Q

Abs that can cause a HDN

A

ABO/Rh, Kell, Duffy

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2
Q

Abs that may cause HTR

A

Kidd, ABO incompat.

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3
Q

Abs that may cause Delayed HTR

A

Kidd (jka, jkb), Duffy, Kell, MNS

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4
Q

How are cold agglutinans excluded from testing?

A

cold agglut-absorption

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5
Q

How is rouleaux excluded from testing?

A

saline replacement

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6
Q

What Abs are detected at IS?

A

Lewis, MN, P1

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7
Q

What Abs are detected at 37 degrees?

A

Rh, MN

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8
Q

What Abs are detected at AHG phase?

A

Kell, Duffy and Kidd

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9
Q

Interval between donations

A

8 weeks

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10
Q

minimum Hgb for donation

A

> 12.5

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11
Q

minimum Hct for donation

A

> 38%

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12
Q

maximum volume of blood drawn during donation

A

525 mL (normal 450 mL)

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13
Q

minimum body weight for donation

A

110 lbs

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14
Q

max body temp for donation

A

37.5/ 99.5

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15
Q

how long is the deferred period if person spent time in a malaria area?

A

1 year

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16
Q

how long is the deferral after having malaria?

A

3 years

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17
Q

what blood type is used for emergency release and alternate blood selection?

A

O pos

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18
Q

Refrigerator temp for RBCs

A

1-4 degrees

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19
Q

shelf life after breakage of hermetic seal

A

24 hrs

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20
Q

length of time recipient samples are saved for

A

7 days

21
Q

temp range during whole blood shipping

A

1-10 C

22
Q

reason to discard a unit of blood

A

hemolyzed

clots

23
Q

which blood group has the most reactivity with anti-H

A

Group O is strongest

24
Q

hemophiliac patient would need what type of blood component?

A

cryo (contains concentrated fibrinogen and factor VIII)

25
Q

what is unique about the Lewis system

A

only blood group system not manufactured by the RBCs.
pregnant women may present Le(a-b-) and produce Lewis Abs even though true phenotype is Le(a-b+). can show in saliva and tears

26
Q

what Abs are found in Bombay individuals?

A

ALL

Anti-A, Anti-B, Anti-A,B, H

27
Q

what blood group Ags are enhanced by enzymes?

A

Lewis, Rh, Kidd

28
Q

what blood group Ags are destroyed by enzymes?

A

Duffy, MNS

29
Q

what would you expect if a Rh neg patient who has never been transfused or pregnant was transfused with pos donor blood?

A

no transfusion reaction because no Abs are present due to no previous exposure

30
Q

when should Rhogam be given

A

Rh - mother Rh+ baby

31
Q

define elution

A

used to remove Abs that may be bound to the RBCs

32
Q

define forward typing

A

using forward known serum Abs to detect unknown Ags

33
Q

define DAT

A

used to diagnose HDN, HTR and AIHA
if + perform an elution to remove Ab to ID specific eluate
(( Direct Coombs use patient cells))

34
Q

define polyspecific

A

has both complement and IgG

35
Q

what is the anti-A1 lectin used to detect

A

used with A1-ABO discrepancy

36
Q

where do you find whartons jelly

A

on cord blood cells

37
Q

why aren’t reverse blood groupings done on newborns

A

no developed Abs

38
Q

define febrile nonhemolytic reaction

A

chills, fever, increase in temp by 2 degrees

39
Q

what could a weak supgroup of A cause

A

ABO discrepancy

40
Q

what would you use distinguish between an A1/A2 discrepancy?

A

dolichus Biflorus

41
Q

if the mother is O and the baby is A and there is HDN what would you transfuse with?

A

Group O blood

42
Q

what would be the next step if cord blood and mother sample have a strong + DAT?

A

elution

43
Q

would A2B and anti-A1 cause a discrepancy?

A

yes

44
Q

why are cells washed in the AHG test?

A

to prevent neutralization by globulins

45
Q

what is the reason for a mixed field result on a DAT for a patient who has been previously transfused

A

2 cell population in the patients blood

46
Q

what type of sample do you need for compatibility testing?

A

fresh serum/plasma

47
Q

why do you need a fresh serum sample for compatibilty

A

to preserve complement

48
Q

what type of elution is required for HDN

A

Acid Elution

49
Q

what is a cause for deferral during blood donation

A

if they tested positive for HBsAg