Practice Questions Module 3&4 Flashcards

1
Q

The effects of vasodilation during an inflammatory response cause which of the following?

a. Decreased blood Viscosity
b. Slower Blood Velocity
c. Decreased Vascular Permeability
d. None of the above

A

B

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2
Q

Which of the following is a role of histamine when released by mast cells?

a. Increased Vascular Permeability
b. Increased pain receptor stimulation
c. Decreased Vascular Permeability
d. Decreased Neutrophil Chemotaxis

A

A

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3
Q

Which of the following result when histamine attaches to the H1 receptor? Select all that apply.

a. Smooth Muscle Contraction
b. Increased Chemotaxis
c. Increased Gastric Acid Secretion
d. Stimulation of Prostaglandin Synthesis

A

A, B, D

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4
Q

Which chemical mediator is responsible for prolonged asthma symptoms such as bronchoconstriction and inflammation?

a. Histamine
b. Cytokines
c. Prostaglandins
d. Leukotrienes

A

D

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5
Q

Which of the following are an active modulator of allergic reactions in the immune system?

a. Monocytes
b. Basophils
c. Eosinophils
d. Natural Killer (NK) Cells

A

C

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6
Q

__________ directional movement of cells along a chemical gradient attracting eosinophils and neutrophils to the site of inflammation.

a. Phagocytosis
b. Chemotaxis
c. Degranulation
d. Synthesis

A

B

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7
Q

What are the functions of interferons? Select all that apply.

a. Protect against viral infection
b. Induction of chemokine production
c. Modulate the inflammatory response
d. Enhance endothelial cell adhesion

A

A, C

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8
Q

Your patient has seasonal allergic rhinitis. Which type of hypersensitivity reaction is this?

a. Type I
b. Type II
c. Type III
d. Type IV

A

A

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9
Q

Your patient has diagnosis of Grave’s disease. Which type of Hypersensitivity reaction is this?

a. Type I
b. Type II
c. Type III
d. Type IV

A

B

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10
Q

Which of the following is a type III hypersensitivity reaction?

a. Hay Fever
b. Autoimmune Thromobocytic Purpura
c. Hashimoto Disease
d. Glomerulonephritis

A

D

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11
Q

Which of the following statement is true regarding Type IV Reactions?

a. Antibody binds to antigen on cell surface
b. The reaction is mediated by T lymphocytes
c. Immune complex are deposited in tissue
d. The reaction is mediated by mast cells

A

B

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12
Q

Which of the following statements are true regarding exotoxins? They: (Select all that apply)

a. damage cell membranes
b. stimulate inflammatory mediators
c. activate second messengers
d. inhibit protein synthesis

A

A, C, D

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13
Q

________ immunity is produced by an individual after natural exposure to an antigen or after immunization.

a. Innate
b. Adaptive
c. Active
d. Passive

A

C

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14
Q

________ immunity produces immunoglobulins that bind to antigens and neutralize their effects.

a. Cellular
b. Humoral
c. Active
d. Passive

A

B

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15
Q

_________ stimulates the proliferation of T cells and B cells during inflammation

a. Interleukins
b. Interferons
c. Tumor Necrosis Factor
d. Transforming Growth Factor

A

A

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16
Q

Catecholamines decrease which of the following immune system cells during acute and chronic stress?

a. Macrophages
b. Natural Killer Cells
c. B Lymphocytes
d. T Lymphocytes

A

B

Pg 345 table 11-2 ‘Physiologic Effects of Catecholamines’ under ‘lymphoid tissue’ it states “acute and chronic stress inhibits several components of innate immunity, particularly decreasing number of natural killer cells.” As I was reading page 346, the paragraph you cited, it does talk about a transient, short term (approx 2 hour) elevation of NK cells after an acute elevation of catecholamine levels, and gives the example of injection with epinephrine in healthy subjects. So I have read in the literature to see exactly what this discrepancy is about and found that there appears to be other references that support a very short elevation in NK cells from 1-2 hours after a stressor, followed by a subsequent decrease in longterm NK levels. So this question would be more accurate in a chronic stress situation, there would be a decrease in NK cells.

17
Q

_______________ interfere with insulin signaling leading to insulin resistance in stress, obesity, and Type 2 Diabetes.

a. Pancreatic Beta Cells
b. Cortisol
c. Proinflammatory Cytokines
d. Free Fatty Acids

A

C

18
Q

___________ suppress gene mutations by encoding proteins involved in repairing damaged DNA.

a. Tumor Suppressor Genes
b. Proto-oncogenes
c. Caretaker Genes
d. Dominant Oncogenes

A

C

19
Q

In a normal, non-mutant state, an oncogene is referred to as a:

            a. basal cell
            b. target cell
            c. caretaker gene
            d. proto-oncogene
A

D

20
Q

Chronic inflammation causes cancer by:

a. increasing vasodilation and permeability that alter cellular response to DNA damage
b. liberating lysosomal enzymes when the cells are damaged that initiates mutations
c. releasing compounds such as reactive oxygen species that promotes mutations
d. increasing the abundance of leukotrienes that are associated with some cancers.

A

C

21
Q

what type of immunity is produced when an immunoglobulin crosses the placenta?

a. passive acquired
b. active acquired

c passive innate

A

A