Practice questions Flashcards

1
Q

A drug interaction that occurs when the combined effect of 2 drugs taken together decreases the effect of the drugs individually

A

Antagonism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What drugs can cause interaction with Warfarin

A

Aspirin, antibiotics or tylenol (acetaminophen)= increased bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

examples of Calcium channel blocker

A
  • Diltiazem (Tiazac)

- pine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the greatest danger of taking OTC antacids?

A

Can affect the absorption of other drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drug-disease interaction of aspirin

A

salicylates- in toothpaste, food preservatives
nasal polyps
causes asthmatic attacks or diff breathing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

side effects of opioids

A

constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What drugs make up the the “triple whammy”

A

ACE Inhibitors + diuretics + NSAIDS
ACE inhibitors- pril
Can cause renal impairment when taken together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drug-drug interactions

A

Diltiazem & erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

side effects of furosemide

A

hyperglycemia, hypotension, allergic reaction

-reduces fluid retention (edema)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Examples of adverse drug reaction

A

idiosyncrasy= eg- allergy to air
Teratogenic effect= birth defects
anaphylaxis= life-threatening allergic reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Brand name and S/E of Trazadone

A

Desyrel

S/E= drowsiness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Effects of opioid analgesics like codeine etc

A

lower HR and respiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is digitalis

A

used to strengthen the contractions of the heart muscle

Overdose= GI disturbance, cardiac arrhythmia, blurred vision

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

S/E of antiprotozoal drugs (malarial drugs)

A

vivid dreams, abdominal pain, HA, N/V, hypotension, visual disturbance, insomnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

S/E of Olanzapine (Zyprexa)

A

Antipsychotic; schizophrenia & bipolar disorder

S/E: orthostatic hypertension, syncope related to low BP, weight gain, neuroleptic sensitivity, Parkinsonism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Generic of Xanax

A

Alprazolam
Schedule IV
Benzodiazepine; GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Beta II Agonist drugs

A

-Albuterol

used for COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

examples of NSAIDs

A

ibuprofen, celecoxib (Celebrex), aspirin, naproxen, nabumetone, meloxicam, etodolac, diclofenac, indomethacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Drug class for antibiotics, antivirals, antifungals

A

anti-infective

20
Q

Which drug class has the suffix -olol

A

Beta Blockers
Cardiovascular
Eg: metoprolol (Lopressor & Toprol XL) , Atenolol (Tenormin)

21
Q

The generic name for Cefzil?

A

Cephalosporin- antibiotics

22
Q

Schedule IV controlled substances

A

Sleep aids + benzodiapines

  1. Ativan (Lorazapem)
  2. Ultram (Tramadol)
  3. Restoril ( Temazepam)
  4. Soma (Carisprodol)
  5. Ambien (zolpidem )
  6. Xanax (Alprazolam)
  7. Lunesta ( eszopiclone)
  8. valium ( diazepam)
  9. Librium ( Chlordiazepoxide)
  10. Klonopin (Clonazepam)
23
Q

How many refills within what time period can be authorized for schedule IV drug?

A

5 refills within a 6-month period

24
Q

How many refills can be authorized for a schedule II drug

A

Zero refills

25
Q

Schedule II controlled drugs

A
Oxycodone (Roxicodone) 
Adderall
Opium
Vicodin (Hydrocodone/ acetaminophen) 
Percocet ( Oxycodone/ Acetaminophen) 
Vyvanse ( Lisdexamfetamine) 
Cocaine
Morphine
Demerol (Meperidine) 
Concerta ( methylphenidate)
26
Q

Which government branch is responsible for assigning schedules of controlled substances

A

US Attorney General

27
Q

Do pharmacists hired by hospitals/institutions need to register to handle controlled substances

A

No

28
Q

What are the constituents of Allegra-D

A

Fexofenadine HCl & Pseudoephedrine HCl

29
Q

ROMAN NUMERALS

A

M- 1000
C- 100
L- 50
D- 500

30
Q

Joint Commission

A

accredits health care institutions based on pt care & safety standards

31
Q

Safety Data Sheets (SDS)

A

Details chemical products, potential dangers assx with these chemicals & measures taken in case of exposure

32
Q

Occupational Safety and Health Administration (OSHA)

A

Ensures a safe and healthy workplace

33
Q

In a horizontal flow hood, how far should one work inside the hood?

A

6 inches

34
Q

what can the direct mixture of calcium gluconate and potassium phosphate soln for injection cause

A

precipitate

35
Q

Lactated Ringer’s solution

A

contains Na, Ca, K salts

Used for IV irrigation

36
Q

what ingredient in TPN may interact with Warfarin

A

Vit K- renders it ineffective

37
Q

Herbal preparation used for depression and possible immune system benefits

A

St John’s wort

Not approved by FDA

38
Q

functions of physicians regarding the use of investigational drugs

A
  1. obtain approval from the IRB
  2. explain drug benefits & risks to pt and obtained a signed consent
  3. send a copy of consent form to pharmacy

Pharmacies
-stores and dispenses the drug

39
Q

Schedule III controlled drugs

A
  1. Vicoprofen- oxycodone/ibuprofen

2. Fiorinal- Butalbital, aspirin & caffeine

40
Q

Drug-Anecdote

A

Acetaminophen- N-acetylcysteine
warfarin- Vit K
Anthracycline chemotherapy- Dexrazoxane
Benzo- Flumazenil

41
Q

What % of dextrose and sodium chloride are in a liter of D5NS?

A

5% dextrose; 0.9% NS

42
Q

Egs of antifungal agents

A

Fluconazole, Nystatin

43
Q

What is a misbranded drug?

A

Has untrue or incorrect claims or labeling like labeling that does not have appropriate instructions for use or warning specific to the drug

44
Q

X’tics of filling a C-II drug

A
  1. Can be partially filled if the remainder is available within 72 hours
  2. Emergency fill is allowed; Dr must provide the pharmacy with a hard copy within 7 days
  3. Can be hard or soft copy but needs to be signed by a Dr
45
Q

Drugs that cannot be delivered via the pneumatic tube system

A
  1. Gemcitabine (chemo drug)
  2. Pegfilgrastim ( proteins can denature)
  3. Abciximab (denatured)
46
Q

Constituents of various insulins

A
  1. Lantus- Insulin glargine
  2. Novolog- Insulin aspart
  3. Humalog (Apidra)- Insulin lisper
  4. Levemir- Insulin detemir