Practice Questions Flashcards

1
Q
29 year old female
No known PMHx
Nil regular medications
New relationship
Wants to go back on COCP
Up to date with CST 

What are the 5 most important questions in hx to explore before prescribing her COCP?

A

FHx of thromboembolic event
Could she be pregnant/last menstrual period
Does she smoke
Current breast feeding
New pattern of headache to suggest migraine
Previous compliance issue with pill

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2
Q
29 year old female
No known PMHx
Nil regular medications
New relationship
Wants to go back on COCP
Up to date with CST 

What are 2 important findings in physical exam that you would need to document in her medical record?

A

BMI/Weight

Blood pressure

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3
Q

What are 3 management options for tinea/pityriasis veriscolor?

A

Topical ketoconazol/clotrimazole/selenim suffice/terbinafine (shampoo/cream) for 2/52

Advise that moistre is the usual underlying cause of this yeast-infection

Explain that the discolouration will take long time to resolve

Oral fluconazole/itraconazole

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4
Q
75 year old male
2 year hx of LUTS - slow stream, hesitancy, nocturia (3x/night), daytime frequency and urgency
Nil PMHx
Nil regular meds
FHx: Father TURP @ 70 years

In assessing this patient, what further information do you need to ask (List 6)

A

Family hx of Prostate Ca

Haematuria

Rapid deterioration of symptoms

Impact on quality of life

Dysuria

Constipation

Incomplete emptying sensation

Polyuria/Polydipsia

Weight loss

Bone pain

Possibility of STI

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5
Q
75 year old male
2 year hx of LUTS - slow stream, hesitancy, nocturia (3x/night), daytime frequency and urgency
Nil PMHx
Nil regular meds
FHx: Father TURP @ 70 years

Apart from BPH, give 5 more likely differential diagnoses for this presentaiton

A

Prostate cancer

Urethral stricture

Overactive bladder

Infections: Urinary tract infection

Interstitial cystitis

Bladder stone

Diabetes

Polydipsia /Excessive fluid intake

Constipation

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6
Q
75 year old male
2 year hx of LUTS - slow stream, hesitancy, nocturia (3x/night), daytime frequency and urgency
Nil PMHx
Nil regular meds
FHx: Father TURP @ 70 years

Give the main 4 relevant features of physical exam to identify the cause of his presentation

A

Abdominal examination for bladder size

External genitals examination

DRE

Neurological examination of perineum/lower limb

Vital signs

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7
Q
75 year old male
2 year hx of LUTS - slow stream, hesitancy, nocturia (3x/night), daytime frequency and urgency
Nil PMHx
Nil regular meds
FHx: Father TURP @ 70 years

In addition to urinary tract US, what investigations would you order to assess a man with moderate to severe LUTS (List 4)

A

Urinanalysis & MSU for MCS if UA positive

Fasting glucose

UEC

PSA

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8
Q
75 year old male
2 year hx of LUTS - slow stream, hesitancy, nocturia (3x/night), daytime frequency and urgency
Nil PMHx
Nil regular meds
FHx: Father TURP @ 70 years

What are the main findings in urinary tract US that will assist you in your management of this patient? (List 4)

A

Estimate prostate size (normal is <25cc)

Estimate residual volume (>100ml may require further ix)

Exclude bilateral hydronephrosis 2nd to chronic retention

Exclude bladder stones and larger bladder tumours

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9
Q
75 year old male
2 year hx of LUTS - slow stream, hesitancy, nocturia (3x/night), daytime frequency and urgency
Nil PMHx
Nil regular meds
FHx: Father TURP @ 70 years

Examination and Ix are consistent with a diagnosis of moderate BPH. What are the 2 pharmacological treatment options you may consider

A

Alpha blockers - tamsulosin, prazosin

5-alpha reductase inhibitors - finasteride, dutasteride

Combination therapy - tamsulosin/dutasteride

Anticholinergic - oxygbutynin, solifenacin

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10
Q
75 year old male
2 year hx of LUTS - slow stream, hesitancy, nocturia (3x/night), daytime frequency and urgency
Nil PMHx
Nil regular meds
FHx: Father TURP @ 70 years

What are 4 possible long-term complication of BPH if left untreated?

A

Acute urinary retention

Recurrent UTIs

Macroscopic haematuria

Chronic urinary retnetion

Bladder stones

Bilateral hydronephrosis with renal impairment

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11
Q
19 year old female
Ground crew for Qantas 
Attends for pre-employment health assessment
PMHx: long-standing mild-moderate asthma
Meds: Salbutamol - OTC
Non-smoker

In order to assess asthma control level - what are 4 important questions you need to ask?

A

Frequency of daytime sx

Frequency of reliever use

Frequency of night time sx

Limitation on exercise tolerance

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12
Q
19 year old female
Ground crew for Qantas 
Attends for pre-employment health assessment
PMHx: long-standing mild-moderate asthma
Meds: Salbutamol - OTC
Non-smoker

Based on further hx and assessment you decide to start this patient on a preventer

What are 7 main features of asthma management?

A

Education about chronic nature of asthma requiring lifelong treatment

Preparing an asthma action plan

Immunisation for common respiratory infections including influenza

Educaiton on proper use of asthma devices

Annual spirometry

Regular review to assess control level

Identify and avoid asthma triggers

Keeping diary of PEFR

Regular daily exercise 30min/day

Maintaining the optimal body weight

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13
Q
19 year old female
Ground crew for Qantas 
Attends for pre-employment health assessment
PMHx: long-standing mild-moderate asthma
Meds: Salbutamol - OTC
Non-smoker

Based on further hx and assessment you decide to start this patient on a preventer.

Patient re-presents in 4 weeks for planned review. Sx are consistent with sbuoptimal asthma control

What are 6 possible cause of her poor response to treatment?

A

Poor technique with use of asthma devices

Poor compliance with medication

Prescribed preventer not sufficient/inappropriate

Ongoing exposure to triggers (stress/allergens)

Underlying pathology other than asthma

Wrong diagnosis

Occupational exposure to triggers at the airport

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14
Q

6/52 old female baby attends 6-week check with Mum
Uncomplicated pregnancy.
Born at term
NVD
O/E: Mild jaundice in sclera, face and upper trunk

No jaundice at birth or in early newborn period
Mum not sure when jaundice started

What further hx will you ask (6)?

A

Stool colour(2)

Urine colour (2)

Has been unwell/fever (2)

Is she breastfed (2)

Feeding frequency/wet nappies (1)

FHx of haemolytic disease/G6PD, spherocytosis (1)

FHx of Gilbert Sx (1)

Weight gain since birth (1)

Hx of maternal hepatitis (1)

Has she had the heel prick test at birth (1)

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15
Q

6/52 old female baby attends 6-week check with Mum
Uncomplicated pregnancy.
Born at term
NVD
O/E: Mild jaundice in sclera, face and upper trunk

No jaundice at birth or in early newborn period
Mum not sure when jaundice started

Bloods show: FBC/EUC - normal
Total serum bilirubin 180 (NR<200), conjugated fraction 68 (NR <34)

What is the single most likely diagnosis?

A

Neonatal cholestasis

Biliary atresia

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16
Q

6/52 old female baby attends 6-week check with Mum
Uncomplicated pregnancy.
Born at term
NVD
O/E: Mild jaundice in sclera, face and upper trunk

No jaundice at birth or in early newborn period
Mum not sure when jaundice started

Bloods show: FBC/EUC - normal
Total serum bilirubin 180 (NR<200), conjugated fraction 68 (NR <34)

What is your next single management step?

A

Urgent referral to Paediatric team

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17
Q

78 year old female, aged care facility

PMHx:
Controlled HTN
Mild dementia

Ongoing oedema and erythema over both lower legs for a few months.
Failed to respond to oral antibiotics.

Systemically well, normal vital signs, no fever

Photo: bilateral lower limb erythema with occasional vesicles

What are the 2 most likely differential diagnoses that can explain this presentation?

A

Stasis (venous) dermatitis (2)

Contact dermatitis (1)

Lipodermatosclereosis (1)

Pretibial myxedema (1)

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18
Q

78 year old female, aged care facility

PMHx:
Controlled HTN
Mild dementia

Ongoing oedema and erythema over both lower legs for a few months.
Failed to respond to oral antibiotics.

Systemically well, normal vital signs, no fever

Photo: bilateral lower limb erythema with occasional vesicles

What are 4 features of management based on provisional diagnosis

A

Measure ABPI to assess arterial suplly (1)

Graduated compression stockings (2)

Elevate feet when sitting/in bed (2)

Apply a potent topical steroid (Bethametasone Diproprionate 0.05%) (2)

Take regular walks /exercise (1)

Use a moisturising cream (1)

Vascular surgeon opionion re: vascular veins (1)

Soap free wash (1)

Frusemide 40mg/daily (1)

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19
Q

78 year old female, aged care facility

PMHx:
Controlled HTN
Mild dementia

Ongoing oedema and erythema over both lower legs for a few months.
Failed to respond to oral antibiotics.

Systemically well, normal vital signs, no fever

Photo: bilateral lower limb erythema with occasional vesicles

What are 5 possible iatrogenic complications that this patient may face should they go to hospital?

A

Hospitla acquired infections - UTI, pneumonia, cannula site (2)

Falls in an unaccustomed environment (2)

Delirium/confusion (2)

Medication errors (2)

Pressure sores (2)

Thromboembolism/DVT (1)

Mental health issues - depression (1)

Constipation (1)

Deconditioning (1)

Insomnia (1)

Malnutrition (1)

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20
Q
21 year old male, migrant from PNG
'cannot shake this cold'
8/52 of productive cough with blood
Nil regular meds
Nil PMHx

Give 4 most likely diagnoses for this presentation

A

Pulmonary tuberculosis (4)

Pertussis (3)

Bronchiectasis (3)

Bronchitis/Post-infective cough (3)

Asthma flare due to exposure in new environment (2)

Post-nasal drip/Rhinosinusitis (2)

Pneumonia (1)

GORD (1)

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21
Q
21 year old male, migrant from PNG
'cannot shake this cold'
8/52 of productive cough with blood
Nil regular meds
Nil PMHx

Give 3 initial investigations you would order to clarify the diagnosis:

Chest High-Resolution CT 
Sputum for acid fast bacilli
Urine MSU
FNA
RBC morphology of sputum
Sputum for cell cytology
Bronchoscopy and biopsy under direct vision
LFT
Spirometry
CT chest with contrast
ABG
Oesophgeal manometry & 24 hr pH
Sinus CT
Methacholine Challenge Test
CXR
Sputum for MCS
Sputum for mycoplasma PCR
Nasopharyngeal swab for influenza PCR
A

Sputum for acid fast bacilli (2)

CXR (2)

Sputum for MCS (2)

22
Q
35 year old female
New pt, accompanied by friend
Lying down with lights dimmed as she has had a headache for 12/24
Feels like vomiting 
Letter from another GP stating: PMHx:
Migraine - pethidine injections

Give the 4 most important steps in assessing the situtation further

A

Check drug/doctor shopper hotline (2)

Take full history of headache (2)

Attempt to contact treating doctor (2)

Examine the patient - including assessing for evidence of drug abuse (2)

Examine for other causes of headache (2)

Explore past treatment hx (2)

23
Q
35 year old female
New pt, accompanied by friend
Lying down with lights dimmed as she has had a headache for 12/24
Feels like vomiting 
Letter from another GP stating: PMHx:
Migraine - pethidine injections

Give 3 management steps

A

Confirm practice policy not to give pethidine for migraines (2)

Appropriate alternative analgesia such as NSAIDs (2)

Antiemetics i.e. metoclopramide (2)

Triptan medication i.e. sumatriptan (2)

24
Q

55 year old female
New pt, recently relocated
Previous GP has found abnormal tests that she would like to discuss with you
Marocytic anaemia with low vitamin B12. Normal folate

Other than pernicious anaemia, give the 4 most likely causes of B12 deficiency

A

Strict vegiterian diet (2.5)

(Atrophic) Gastritis (2.5)

Crohn’s (2.5)

Medications - Omeprazole, metformin (2.5)

Malabsorption disease - coeliac (2.5)

Previous gastrectomy/bariatric surgery (2.5)

Chronic alcoholism (2.5)

25
Q

55 year old female
New pt, recently relocated
Previous GP has found abnormal tests that she would like to discuss with you
Marocytic anaemia with low vitamin B12. Normal folate

Findings are suggestive of pernicious anaemia. What are the 2 tests you would order to make a definitive diagnosis?

A

Anti parietal cell antibody (2)

Anti intrinsic factor antibody (2)

26
Q
36 year old male
Nil PMHx
Training for a marathon
Has noticed blood in urine
Blood on urine dipstick

What are the 5 most likely differential diagnoses of his haematuria?

A

Exercise-induced haematuria (3)

Urinary Tract Infection/Cystitis (2)

Polycystic Kidney Disease (1)

Trauma - renal or urethral (1)

Glomerulonephritis/IGA nephropathy (1)

Nephrolithiasis/Stone (1)

Benign renal mass - angiomyolipoma (1)

Urogenital carcinoma/Bladder carcinoma/renal cell carcinoma (1)

27
Q
36 year old male
Nil PMHx
Training for a marathon
Has noticed blood in urine
Blood on urine dipstick
What are the 3 most important investigations/examination findings from the list below:
Urine osmolality
Urine sodium concentration
Urine for crystal assessment
CT KUB
PSA
Abdominal Xray
RBC morphology 
Spiral CT/CT Urogram
Urine MCS
Urea and Electrolytes
Uric Acid
ECG
CXR
Cystourethrogram
A

RBC morphology (2)

Spiral CT/CT Urogram (2)

Urine MCS (2)

Urea and Electrolyte (2)

28
Q
68 year old male
2-3 days of one-sided persistent throbbing headache over left temple
Never had similar headache in the past
PMHx: Hypercholesterolaemia, Heartburn
Meds: Simvastatin, Omeprazole
Tender over area of headache

What is the single most likely cause of this presentation

A

Left side temporal arteritis/Giant cell arteritis (2)

29
Q
68 year old male
2-3 days of one-sided persistent throbbing headache over left temple
Never had similar headache in the past
PMHx: Hypercholesterolaemia, Heartburn
Meds: Simvastatin, Omeprazole
Tender over area of headache
Which 1 of the following investigations would be more helpful in  confirming your clinical diagnosis?
Anti CCP
FBE
LFT
U&E
Brain CT
Ultrasound of the carotid
ESR
ANA
Anti CCP
Troponin
A

ESR (2)

30
Q

68 year old male
2-3 days of one-sided persistent throbbing headache over left temple
Never had similar headache in the past
PMHx: Hypercholesterolaemia, Heartburn
Meds: Simvastatin, Omeprazole
Tender over area of headache
A diagnosis of giant cell arteritis has been confirmed

What are 5 key features of management

A

Long term prednisolone rx starting at 60mg/day (2)

Low dose aspirin 100mg/day (2)

Explanation of autoimmune nature of the condition (2)

Warn about possible impact on vision as a result of poor treatment (2)

Regular review of inflammatory markers (2)

Rheumatologist/Neurologist involvement (2)

Explain side effects of long term corticosteroid treatment - weight gain (2)

Fracture prevention plan (1)

Risk assessment of cardiovascular disease (1)

Advise to take regular PPI considering on aspirin + prednisolone (2)

31
Q
75 year old female
PMHx: Hiatus hernia, GORD
Meds: Esomeprazole
Presents for  annual influenza vaccine
Found to have irregularity in  pulse 
ECG = AF
Which 4 of the following investigations will assist you to identify a possible underlying cause for her  ECG findings
High resolution chest CT
ESR
CRP
Bone scan
CXR
CT abdomen
FOBT
Fasting BSL
Ferritin
FBE
Lipid profile
LFT
Mammogram
Serum Protein Electrophoresis
Pelvic US
TFTs
Vitamin B6
Creatinine/Urea/Electrolytes 
Cortisol
CTPA
D-Dimer
A

CXR

FBE

TFTs

Creatinine/Urea/Electrolytes

32
Q
75 year old female
PMHx: Hiatus hernia, GORD
Meds: Esomeprazole
Presents for  annual influenza vaccine
Found to have irregularity in  pulse 
ECG = AF

What are 3 main goals in management of this new cardiac problem (There is no need to name medications)

A

Rate control (2)

Rhythm control (2)

Prevention of thromboembolic event (2)

33
Q
42 year old female
Lump outer aspect of right breast
2cm  size lump
PMHx: Obesity
Meds: COCP
BMI 33
Ex-smoker
Never been pregnant

What are 7 specific relevant questions you need to ask when taking a focused hx about this new lump?

A

Recent trauma to this breast (fat necrosis) (1)

Pain/tenderness over the lump (1)

Any nipple discharge/inversion (1)

Any Axillary lump (1)

Any previous breast lumps (1)

Eczema over the areola (1)

FHx: Breasth Ca/Ovarian Ca (1)

Age of menarche (1)

Relation with menstrual cycle / Last menstruation (1)

34
Q
42 year old female
Lump outer aspect of right breast
2cm  size lump
PMHx: Obesity
Meds: COCP
BMI 33
Ex-smoker
Never been pregnant

What are 6 important steps in breast physical examination?

A

Inspection of skin for changes - dimpling/inversion/tethering (1)

systemic palpation of all quadrants of both breasts (1)

Identify the exact location of the lump (1)

Examination of relevant lymph nodes - axillary, supraclavicular (1)

Palpation for lump specific features - size, mobility/adherence, consistency, shape, margin, tenderness (1)

Adequate exposure of both breasts (1)

Assess for nipple discharge (1)

Inspection of nipples for changes (1)

35
Q
42 year old female
Lump outer aspect of right breast
2cm  size lump
PMHx: Obesity
Meds: COCP
BMI 33
Ex-smoker
Never been pregnant

What are the 5 specific characteristics of the lump that you would like to explore during the examination?

A

Consistency (0.5)

Shape (0.5)

Margins (0.5)

Mobility (0.5)

Depth (0.5)

Tenderness (0.5)

Skin tethering caused by lump (0.5)

36
Q

48 year old male
Attends with wife
PMHx: Marfan’s syndrome, HTN, T2DM, Aortic metallic valve, COPD
Meds: Perindopril, Metformin, Warfarin, Spiriva
You suspect non-compliance as BP and Diabetes are not controlled properly.
Unstable INR

In order to gather more info about compliance what steps can you take? List 4

A
  1. Ask about compliance/side effects of medications (1)

Opportunistically ask wife about medication compliance (1)

Check prescription requests/issuing intervals on the records (1)

Check with pharmacist about prescription dispensing intervals (1)

Organise home medication review (1)

37
Q

48 year old male
PMHx: Marfan’s syndrome, HTN, T2DM, Aortic metallic valve, COPD
Meds: Perindopril, Metformin, Warfarin, Spiriva
You suspect non-compliance as BP and Diabetes are not controlled properly.
Unstable INR

What are the 6 patient characteristics that may impact their compliance with the prescribed medications?

A

Literacy (0.5)

Age (0.5)

Ethnic background (0.5)

Mental Health Issues (depression/memory loss) (0.5)

Physical disabilities (Visual impairment) (0.5)

Socioeconomic level (0.5)

Drug/Alcohol issues (0.5)

Language (0.5)

Belief about the medication (0.5)

38
Q

48 year old male
PMHx: Marfan’s syndrome, HTN, T2DM, Aortic metallic valve, COPD
Meds: Perindopril, Metformin, Warfarin, Spiriva
You suspect non-compliance as BP and Diabetes are not controlled properly.
Unstable INR

What are the 7 possible indications for which you can claim a HMR under current medicare regulations?

A

5 or more regular medications (2)

> 12 doses of medication per day (1)

Recent significant changes made to medications (1)

Medication with a narrow therapeutic index/requiring therapeutic monitoring (1)

Sx suggestive of an ADR (1)

Sub-optimal response to rx (1)

Suspected non-compliance (1)

Difficulty managing own medicines because of literacy/language (1)

Problems or impaired sight, confusion/dementia or other cognitive difficulties (1)

Patients attending a number of different doctors (1)

Recent discharge from a facility/hospital (1)

39
Q
68 year old male
Truck driver
Progressive dyspnoea for 3/12
PMHx: 
Myocardial infarction (15 years ago) - stented
Ex-smoker
HTN
Meds:
Aspirin 100mg mane
Perindopril 5mg mane
Atenolol 50mg mane
Atorvastatin 40mg OD

Apart from cardiac failure, what are 5 most likely causes of dyspnoea?

A

Coronary artery disease (1)

Aortic stenosis (1)

Atrial fibrillation (1)

COPD (1)

Pulmonary fibrosis/Interstitial Lung Disease (1)

Lung cancer (1)

Obesity (1)

Lack of fitness (1)

Anaemia (1)

40
Q
68 year old male
Truck driver
Progressive dyspnoea for 3/12
PMHx: 
Myocardial infarction (15 years ago) - stented
Ex-smoker
HTN
Meds:
Aspirin 100mg mane
Perindopril 5mg mane
Atenolol 50mg mane
Atorvastatin 40mg OD

What are 5 specific questions in hx that will assist you to reach a diagnosis?

A

Orthopnea (1)

Chest pain (1)

Recent weight change (1)

Cough (1)

Palpitation (1)

Exact level of exercise tolerance (1)

Paroxysmal nocturnal dyspnoea (1)

Peripheral oedema (1)

Known recent bleeding (1)

41
Q
68 year old male
Truck driver
Progressive dyspnoea for 3/12
PMHx: 
Myocardial infarction (15 years ago) - stented
Ex-smoker
HTN
Meds:
Aspirin 100mg mane
Perindopril 5mg mane
Atenolol 50mg mane
Atorvastatin 40mg OD

O/E: HR 90bpm regular
BP 150/90mmHg
JVP ?slightly elevated
Chest is clear

Ix confirm diagnosis of congestive cardiac failure

What are the 6 important features of your management?

A

Explanation of the chronic nature of heart failure (1)

Salt intake restriction (<2gram/day) (1)

Fluid intake limit to <1.5L (1)

Change atenolol to cardiac failure specific beta blocker - carvedilol (1)

Gradually increase dose of perindopril to maximum (1)

Daily weight diary (1)

Assure immunisation - influenza/pneumonia (1)

Lifestyle modification with regular exercise/reduce caffeine/reduce alcohol (1)

Involve cardiologist (1)

Add diuretic - Frusemide 40mg/day (1)

Cardiac rehabilitation (1)

Address safety of driving/adverse informing road safety authorities (1)

42
Q
52 year old male
Truck driver
Snoring
Wife reports loud snoring and pauses during the night
Non-smoker
Nil regular meds
Nil PMHx
You suspect OSA

Considering the provisional diagnosis of OSA, what are 5 specific questions you need to ask to further explore this complaint

A

Recent weight gain (1)

Hx of gasping/chocking typical of OSA (1)

Nasal patency/obstruction/issues/trauma/rhinitis (1)

Alcohol intake before bedtime (1)

Daytime sleepiness (1)

Impact on driving / recent accidents (1)

Morning headaches (1)

Decreased concentration (1)

Irritability/lowered mood (1)

Sexual dysfunction (1)

43
Q
52 year old male
Truck driver
Snoring
Wife reports loud snoring and pauses during the night
Non-smoker
Nil regular meds
Nil PMHx
You suspect OSA

What are 4 relevant feature of your physical exam to assess for OSA

A

BMI (1)

Neck circumference (1)

Assess mandible for retrognathia (1)

Check nasal patency (1)

Assess mallampati score / Tonsillar hypertrophy (1)

Blood pressure (1)

Heart auscultation /Cardiovascular examination (1)

44
Q
52 year old male
Truck driver
Snoring
Wife reports loud snoring and pauses during the night
Non-smoker
Nil regular meds
Nil PMHx
You suspect OSA

BMI = 26
BP 130/82mmHg
Sleep study reveals moderate to severe OSA

What are 5 main features of management?

  • Not to drive until the sleep problem has been dealt with
  • Use mouth splint
  • Reduce alcohol intake late at night
  • Avoid spicy food
  • Regular exercise at least 30mins most days
  • CPAP treatment under sleep physician supervision
  • Magnesium supplementation at night
  • Offer medical certificate for work
  • Recommend afternoon nap
  • Allocate enough time for adequate sleep at night
  • Reduce salt in diet
  • Provide work cover certificate
  • Organise ABPM
  • Offer holter ECG
  • Refer for stress ECHO
  • ENT review
  • Provide carer certificate for wife
  • Recommend annual influenza immunisation
  • Advise to have annual blood test to monitor for LFT
  • Organise non-urgent carotid doppler US
A

Not to drive until the sleep problem has been dealt with (1)

Reduce alcohol intake at night (1)

Regular exercise at least 30mins most days (1)

CPAP treatment under sleep physician’s supervision (1)

Offer medical certificate for work (1)

Allocate enough time for adequate sleep at night (1)

45
Q
4 year old female
Attends with Mum
Vomiting since 0300
Not interested in eating
Sipping on water - brings everything straight up
BNO
No urinary sx
Perfectly well yesterday
No signs of significant dehydration

What is the most likely cause of Jade’s presentation?

A

Viral gastroenteritis/gastritis (3)

46
Q
4 year old female
Attends with Mum
Vomiting since 0300
Not interested in eating
Sipping on water - brings everything straight up
BNO
No urinary sx
Perfectly well yesterday
No signs of significant dehydration

What are the 4 most important causes of this presentation that should not be missed?

A
  1. Metabolic conditions - DKA (2)
  2. Poisoning (1)
  3. Head injury - concussion (1)
  4. Sepsis - pneumonia (1)
  5. Gastrointestinal obstruction (1)
47
Q
4 year old female
Attends with Mum
Vomiting since 0300
Not interested in eating
Sipping on water - brings everything straight up
BNO
No urinary sx
Perfectly well yesterday
No signs of significant dehydration

You confirm gastroenteritis as the dx

What are the 5 key features of your management?

A

Explain self-resolving nature of viral infection (1)

Plan proper oral hydration at home (2)

Exclude from child care until 48hour after last vomit/diarrhoea (1)

Warn about alarming signs which need review (safety net) (1)

Proper hand wash advice (1)

Antiemetic - Ondansetron 4mg wafer BD (1)

Advise that diarrhoea may follow (1)

48
Q
38 year old female 
Nurse
Palpitation, lethargy and weight loss
Nil PMHx
Nil  regular medications
Etonogestrel contraceptive implant 2/12

TSH <0.01mIU/L (normal range 0.5-4)
T4: 27pmol (normal 10-25)
T3: 6.8pmol/L (normal range 3.1-5.4)

What are the 4 likely causes of her thyroxicosis apart from Graves disease?

A

Toxic multi-nodular goitre (1.5)

Toxic adenoma (1.5)

Exogenous thyroid hormone (1.5)

Subacute thyroiditis (1.5)

49
Q
38 year old female 
Nurse
Palpitation, lethargy and weight loss
Nil PMHx
Nil  regular medications
Etonogestrel contraceptive implant 2/12

TSH <0.01mIU/L (normal range 0.5-4)
T4: 27pmol (normal 10-25)
T3: 6.8pmol/L (normal range 3.1-5.4)

What 2 Ix will be most helpful to confirm clinical suspicion of Graves Disease?

  • Thyroid US
  • Thyroid CT Angiogram
  • CXR
  • ECG
  • Thyroid peroxidase
  • Thyroid MRI
  • Radionuclide thyroid scan
  • TSH receptor antibodies
  • FNA
  • CTPA
  • Radioactive iodine scan
  • Thyroglobulin autoantibodies
  • FBE
  • EUC
  • LFT
  • PTH level
  • ESR
  • Anti SM antibody
  • Anti ds-antibody
  • ANA
A

Radionuclide uptake thyroid scan

TSH receptor antibodies

50
Q
38 year old female 
Nurse
Palpitation, lethargy and weight loss
Nil PMHx
Nil  regular medications
Etonogestrel contraceptive implant 2/12

TSH <0.01mIU/L (normal range 0.5-4)
T4: 27pmol (normal 10-25)
T3: 6.8pmol/L (normal range 3.1-5.4)

Investigations are consistent with Graves. You start the patient on carbimazole 10mg/TDS in consultation with endocrine.

Pt returns to see you in 6/52 with fever, mouth ulcers and sx of gastroenteritis

What is the most important cause of her new sx that you need to consider first?

A

Agranulocytosis or Neutropenia (4)