practice class questions Flashcards
our adaptive immune response is part of which line of defense
third
lymphocytes involved in adaptive immune response
B cells in the plasma and memory cells. T cells- cytotoxic, helper T cells 1 and 2 (type 2 trigger B cells) and memory cells that respond rapidly to antigen recognition
five antibodies
IgA- skin and mucous membranes, first line of defense, breast feeding
IgG- smallest, cross placenta, increase if there is second exposure to a pathogen
IgE- allergic reaciton, basophil and mast cell degranulation
IgM- does not go into tissue, initial responder
IgD- elevated in chronic infection
alloimmunity
cells from another individual of the same species
autoimmunity
body does not differentiate from invader and self
opsonization
labeling and recognizing threat
neutralization
pathogen releases own toxin to immune system and those toxins need to be neutralized
compliment activation
triggering an inflammatory response. IgM, keep pathogen localized
active natural immunity
develop antibodies on your own IgM and IgG
active artificial
vaccination
passive natural
breastfeeding IgG to IgA during placental transfer, short term
passive artificial
inject of antibodies, short term, rabies antibody
type I hypersensitivity
mediated by B cells- antibodies, mediated by IgE, the antibody triggers mast cell degranulation which causes an inflammatory response. Hay fever and eczema
Type II sensitivity
mediated by B cell, IgG directly targets cells or tissues, cell response is mediated by IgM, transfusion reaction when receiving a blood product
type III
mediated by b cells, body develops antigen/antibody complex and deposits in tissues leading to activation of complement, tissue inflammation, IgM and IgG, rheumatoid arthritis