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Practical Third year > pRACTICAL MATCHING PHARMA > Flashcards

pRACTICAL MATCHING PHARMA Flashcards

1
Q

A monoclonal anti-body Calcitonin
Contraindicated in renal impairment D5W
Of limited potency Denosumab
Preferred in cardiac failure Frusemide
Hydrocortisone
Teriparatide
Zoledronic acid

A

A monoclonal anti-body—————————-> Denosumab
Contraindicated in renal impairment———-> Zoledronic acid
Of limited potency————————————> Calcitonin
Preferred in cardiac failure ———————–> Frusemide

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2
Q

Classify the following hypnotics as either suitable to improve sleep latency or sleep duration: Eszopiclone, lorazepam, ramelteon Suvorexant, triazolam, zaleplon

A

Eszopiclone—> Treat Sleep Maintenance insomnia

Lorazepam ——> Treat Sleep Maintenance insomnia

Ramelteon—> Treat Sleep onset insomnia

Suvorexant——–> Treat Sleep Maintenance insomnia

Triazolam——–> Treat Sleep onset insomnia

Zaleplon—> Treat Sleep onset insomnia + For patient with awakening in the

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3
Q
  1. Antidepressants increase serotonin synthesis
  2. Buproprion Serotonin receptor agonist
  3. Buspirone Increase serotonin release
  4. Dextromethorphan Inhibit serotonin uptake
  5. Ergot derivatives Inhibit serotonin metabolism
  6. L-Tryptophan No known relation to serotonin
  7. Linezolid
  8. Lamotrigine
  9. MAO inhibitors
  10. Meperidine
  11. Phenytoin
    18.St. John’s wort
  12. Tramadol
  13. Triptans
A

12 ———————————-> increase serotonin synthesis
9,11,20 —————————> Serotonin receptor agonist
Increase serotonin release
19,18,16,10,7 ——————> Inhibit serotonin uptake
13 ———————————-> Inhibit serotonin metabolism
8, 14, 17 ————————-> No known relation to serotonin

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4
Q
  1. Colorectal surgery Amoxicillin
  2. Coronary bypass grafting. Benziathine penicillin
  3. Hip replacement in a penicillin-allergic patient Cefepine
  4. Infective endocarditis Ciprofolaxin
  5. Meningitis Erythromycin
  6. Spontaneous bacterial peritonitis 1st Gen cephalosporin
  7. Rheumatic fever Gentamicin + metronidazole
    No prophylaxis
  8. Tonsillectomy Piperacillin/tazobactam
    Rifampicin
    Rifaximin
A

Colorectal surgery———————————-> Gentamicin + metronidazole
Coronary bypass grafting ————————> 1st gen cephalosporin
Hip replacement in a penicillin allergic patient–> Erythromycin
Infective endocarditis——————————–> amoxicillin
Meningitis ———————————————-> Rifampicin
Spontaneous bacterial peritonitis————–>Ciprofloxacin
Rheumatic fever ————————————-> Benzathine penicillin
Tonsillectomy—————————————–> no prophylaxis

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5
Q

Mention three alternative antibiotics for typhoid carrier, with duration of treatment, no doses required

A

Amoxicillin ———> 6 weeks
Ampicillin ———> 6 weeks
Ciprofloxacin ———-> 28 days

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6
Q

List antimicrobials for eradication of Group A beta Hemolytic Streptococci (GAS) for penicillin allergic and non-allergic patients.

A

Penicillins (drug of choice):

Penicillin G Or Penicillin V

For patients allergic to penicillin:

Azithromycin Or Clarithromycin

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7
Q

Mention two alternative antibacterial therapies that can be used for the treatment of community-acquired pneumonia in absence of comorbidities and absence of risk factors for MRSA.

A

Amoxicillin every 8 hours

Doxycycline every 12 hours

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8
Q

Mention two alternative antibacterial therapies that can be used for the treatment of community-acquired pneumonia for a patient with diabetes mellitus but in absence of risk factors for MRSA.

A

Amoxicillin and Azithromycin
Amoxicillin and Clarithromycin

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9
Q

Mention two alternative antibacterial therapies that can be used for the treatment of hospital-acquired pneumonia in the absence of risk for MRSA and for mortality

A

Penicillin based anti-pseudomonal

Cephalosporin based anti-pseudomonal

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10
Q

Mention two alternative antibacterial therapies that can be used for the treatment of hospital-acquired pneumonia in the presence of risk for MRSA in the absence of mortality risk.

A

One antipseudomonal from Column A plus vancomycin

Aztreonam and Linezolid

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11
Q

Mention two alternative antibacterial therapies that can be used for the treatment of hospital-acquired pneumonia in the presence of risk for MRSA and for high mortality risk.

A

Select antipseudomonal from different classes and Vancomycin

Aminoglycosides and Linezolid

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12
Q

Prophylaxis of Streptococcus pneumonia

A

Vancomycin plus a third-generation cephalosporin

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13
Q

Prophylaxis of Neisseria meningitides

A

Third-generation cephalosporin

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14
Q

Prophylaxis of Hemophilus influenza

A

Third-generation cephalosporin

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15
Q

Prophylaxis of Listeria monocytogenes

A

Penicillin G

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16
Q

Prophylaxis of Herpes simplex

A

Acyclovir

17
Q

Prophylaxis of CMV.

A

Ganciclovir

18
Q

Prophylaxis of Listeria

A

Ampicillin

19
Q

Prophylaxis of Mycoplasma

A

A macrolide

20
Q

Prophylaxis of Mycobacteria.

A

combo of 4 anti-TB drugs

21
Q

Prophylaxis of Helminths.

A

Albendazole

22
Q

Prophylaxis of Fungi.

A

Amphotericin B

Practical Third year (7 decks)

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