Practical Exam 1 Flashcards

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1
Q

What are the phases of mitosis?

A

Interphase, prophase, metaphase, anaphase, telophase, cytokinesis

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2
Q

What are the phases of interphase?

A

G1, S, G2

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3
Q

What occurs in G1 and G2? What is the difference?

A

Growth of cell, G2 has twice the genetic material

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4
Q

Describe prophase

A

chromosomes become visible as paired chromatids and nuclear envelope dissolves

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5
Q

Describe metaphase

A

chromosomes line up along the metaphase plate and spindle fibers attach at the centers

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6
Q

Describe anaphase

A

Spindle fibers pull apart chromatids

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7
Q

Describe telophase/cytokinesis

A

Chromatids move to opposite ends of the cell and cell splits in two

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8
Q

Aneuploidy

A

abnormal number of chromosomes in a haploid set

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9
Q

Nondisjunction in meiosis 1 causes what?

A

effects all four daughter cells, two are missing one chromatid and two have an extra

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10
Q

Nondisjunction in meiosis 2 causes what?

A

effects only half the daughter cells, one has an extra chromatid and one lacks

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11
Q

When do we use the rule of multiplication for genetic statistics?

A

When we want to know the probability of two things happening (i.e. two tails in a row, or getting a recessive allele and passing it on)

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12
Q

When do we use the rule of addition for genetic statistics?

A

When we want to know the probability of mutually exclusive events (i.e. heads or tails, having a heterozygous or homo. dominant genotype)

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13
Q

What is an X-linked dominant pattern of inheritance?

A

Affected male passes trait onto all daughters but no sons, heterozygous female passes onto half her offspring if crossed w unaffected male (ex: Rett syndrome)

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14
Q

What is an X-linked recessive pattern of inheritance?

A

Affects males at higher rates than females, (ex: duchenne muscular dystrophy)

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15
Q

What is a Y-linked recessive pattern of inheritance?

A

Only present in males (ex: hypertrichosis, webbed toes)

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16
Q

Patau Syndrome

A

extra copy of chromosome 13

17
Q

Down Syndrome

A

extra copy of chromosome 21

18
Q

Edward’s Syndrome

A

extra copy of chromosome 18

19
Q

Triple X Syndrome

A

three x chromosomes in females

20
Q

Turner Syndrome

A

One X chromosome missing in females

21
Q

Klinefelter Syndrome

A

Extra X chromosome in males (XXY)

22
Q

XYY Syndrome

A

Males with extra Y chromosome

23
Q

Cri-du-Chat Syndrome

A

Deletion on chromosome 5

24
Q

Fragile X syndrome

A

duplication on X chromosome (both sexes)

25
Q

Acute myelogenous leukemia

A

Translocation with part of chromosome 22 is moved to 9