pr3151_abx_20241028085622 Flashcards
Natural penicillin coverage
Gram +ve:
MSSA(maybe, AST), Streptococcus, Enterococcus, Peptostreptococcus
Gram -ve:
Neisseria meningococcal & gonococci, Treponema(Syphilis)
Penicillinase resistant penicillin
Gram positive ONLY:
MSSA, Streptococcus (Group A,B,C,G)
Aminopenicillins w/o beta lactase inhibitors
Gram +ve:
MSSA, Streptococcus, Enterococcus fecalis, Peptostreptococcus
Gram -ve:
H. influenzae, E. Coli
Aminopenicillins + BL inhibitors
Gram +ve: MSSA, Streptococcus, Enterococcus, Peptostreptococcus
Gram -ve: Bacteroides, H. Influenzae, E.coli, Klebsiella(?), Proteus, ESBL(cystitis only)
Antipseudomonal penicillins
Gram +ve:
MSSA, Streptococcus, Enterococcus, Peptostreptococcus
Gram -ve:
Bacteroides, H. Influenzae, E coli, Klebsiella, Proteus, ESBL(cystitis only), Enterobaxter(cystitis only), pseudomonas
1st Gen Cephalosporins
Gram +ve:
MSSA, Streptococcus G, Peptostreptococcus
Gram -ve:
H. Influenzae, EKP
2nd gen Cephalosporins
Gram +ve:
MSSA, Streptococcus, Peptostreptococcus
Gram -ve:
H. Influenzae, EKP
Note: additional Streptococcus pneumoniae compared to 1st gen
3rd Gen Cephalosporins
Common across Cephalosporins:
Peptostreptococcus, H. Pylori, EKP
Ceftriaxone:
Gram +ve:
MSSA, Streptococcus, Enterococcus(in combination), Peptostreptococcus
Gram -ve:
Enterobacter(cystitis only)
Ceftazidime:
Only have peptostreptococcus for Gram pos coverage
Gram -ve:
Enterobacter(cystities only), Pseudomonas
Both: Neisseria gonorrhoeae
4th gen cephalosporins
Common: Peptostreptococcus, H. Influenzae, EKP
Gram +ve: MSSA, Streptococcus
Gram -ve: ESBL(cystitis only), Enterobacter(non severe infxtion), pseudomonas
5th gen cephalosporins
Common coverage:
Peptostreptococcus, H. Influenzae, EKP
Gram +ve:
MRSA, VRSA, MSSA, Streptococcus
Gram -ve:
Enterobacter(cystitis only), Moraxella
Carbapenems spectrum
Imipenem & Meropenem:
Gram positive:
All in the table except for MRSA & Clostridioide
(MSSA, Streptococcus, Enterococcus, Peptostreptococcus)
Gram -ve:
All in the table (Bacteroides, H. Influenzae, EKP, ESBL, Enterobacter, Pseudomonas
Ertapenem:
Does not cover Pseudomonas & Enterococcus
Aztreonam
Aerobic, Gram negative coverage ONLY, does not cover ESBL
(H. Influenzae, E coli, Klebsiella, Enterobacter, Pseudomonas)
Vancomycin
Gram +ve coverage ONLY
Covers all in the table
Clostridioides (PO only)
Tetracycline spectrum
Atypical (Chlamydia, Mycoplasma, Legionella)
Gram +ve:
MRSA, MSSA, Streptococcus pneumonia, Peptostreptococcus, Bacillus
Gram -ve: H. Influenzae, Rickettsia, Yersinia, Vibrio cholerae
Aminoglycoside spectrum
Mainly aerobic, gram negative coverage
(H. Influenzae, EKP, ESBL, Enterobacter, Pseudomonas)
Gram +ve( combined with penicillins):
MSSA, Enterococcus