pr3151_abx_20241028085622 Flashcards

1
Q

Natural penicillin coverage

A

Gram +ve:
MSSA(maybe, AST), Streptococcus, Enterococcus, Peptostreptococcus

Gram -ve:
Neisseria meningococcal & gonococci, Treponema(Syphilis)

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2
Q

Penicillinase resistant penicillin

A

Gram positive ONLY:
MSSA, Streptococcus (Group A,B,C,G)

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3
Q

Aminopenicillins w/o beta lactase inhibitors

A

Gram +ve:
MSSA, Streptococcus, Enterococcus fecalis, Peptostreptococcus

Gram -ve:
H. influenzae, E. Coli

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4
Q

Aminopenicillins + BL inhibitors

A

Gram +ve: MSSA, Streptococcus, Enterococcus, Peptostreptococcus

Gram -ve: Bacteroides, H. Influenzae, E.coli, Klebsiella(?), Proteus, ESBL(cystitis only)

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5
Q

Antipseudomonal penicillins

A

Gram +ve:
MSSA, Streptococcus, Enterococcus, Peptostreptococcus

Gram -ve:
Bacteroides, H. Influenzae, E coli, Klebsiella, Proteus, ESBL(cystitis only), Enterobaxter(cystitis only), pseudomonas

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6
Q

1st Gen Cephalosporins

A

Gram +ve:
MSSA, Streptococcus G, Peptostreptococcus

Gram -ve:
H. Influenzae, EKP

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7
Q

2nd gen Cephalosporins

A

Gram +ve:
MSSA, Streptococcus, Peptostreptococcus

Gram -ve:
H. Influenzae, EKP

Note: additional Streptococcus pneumoniae compared to 1st gen

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8
Q

3rd Gen Cephalosporins

A

Common across Cephalosporins:
Peptostreptococcus, H. Pylori, EKP

Ceftriaxone:
Gram +ve:
MSSA, Streptococcus, Enterococcus(in combination), Peptostreptococcus

Gram -ve:
Enterobacter(cystitis only)

Ceftazidime:
Only have peptostreptococcus for Gram pos coverage

Gram -ve:
Enterobacter(cystities only), Pseudomonas

Both: Neisseria gonorrhoeae

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9
Q

4th gen cephalosporins

A

Common: Peptostreptococcus, H. Influenzae, EKP
Gram +ve: MSSA, Streptococcus

Gram -ve: ESBL(cystitis only), Enterobacter(non severe infxtion), pseudomonas

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10
Q

5th gen cephalosporins

A

Common coverage:
Peptostreptococcus, H. Influenzae, EKP

Gram +ve:
MRSA, VRSA, MSSA, Streptococcus

Gram -ve:
Enterobacter(cystitis only), Moraxella

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11
Q

Carbapenems spectrum

A

Imipenem & Meropenem:
Gram positive:
All in the table except for MRSA & Clostridioide
(MSSA, Streptococcus, Enterococcus, Peptostreptococcus)

Gram -ve:
All in the table (Bacteroides, H. Influenzae, EKP, ESBL, Enterobacter, Pseudomonas

Ertapenem:
Does not cover Pseudomonas & Enterococcus

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12
Q

Aztreonam

A

Aerobic, Gram negative coverage ONLY, does not cover ESBL
(H. Influenzae, E coli, Klebsiella, Enterobacter, Pseudomonas)

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13
Q

Vancomycin

A

Gram +ve coverage ONLY
Covers all in the table
Clostridioides (PO only)

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14
Q

Tetracycline spectrum

A

Atypical (Chlamydia, Mycoplasma, Legionella)

Gram +ve:
MRSA, MSSA, Streptococcus pneumonia, Peptostreptococcus, Bacillus

Gram -ve: H. Influenzae, Rickettsia, Yersinia, Vibrio cholerae

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15
Q

Aminoglycoside spectrum

A

Mainly aerobic, gram negative coverage
(H. Influenzae, EKP, ESBL, Enterobacter, Pseudomonas)

Gram +ve( combined with penicillins):
MSSA, Enterococcus

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16
Q

Tigecycline spectrum

A

Covers resistant strains:
Gram positive:
MRSA, Multi-drug resistant Streptococcus, VRE

Gram -ve: ESBL, useful against carbapenem resistant strains

17
Q

Macrolide spectrum

A

For respiratory and STD infections

Common coverage:

Atypicals (Chlamydia, Mycoplasma, Legionella)

Gram +ve:
MSSA, Streptococcus, Peptostreptococcus

Gram -ve:
H. Influenzae

Clarithromycin:
H. Pylori

Azithromycin:
Moraxella, enteric pathogens( campylobacter, salmonella, shigella, vibrio cholerae)

18
Q

Clindamycin spectrum

A

Anerobic infections

Gram +ve:
MRSA, MSSA, Streptococcus, Peptostreptococcus, Clostridiodes perfringen

Gram -ve:
Bacteroides

19
Q

Linezolid spectrum

A

Gram +ve only:
Resistant strains of gram +ve drugs:
MRSA, VRE, VRSA, multi drug resistant streptococci,
Listeria

20
Q

Fluoroquinolones spectrum

A

Common spectrum:
Gram -ve: H. Influenzae, EKP, ESBL, Enterobacter

Ciprofloxacin:
Mainly gram -ve: Pseudomonas, Shigella, Salmonella, Campylobacter

Gram +ve:Enterococcus (ucUTI), Bacillus

Levofloxacin:
Atypicals

Gram +ve: MRSA, MSSA, Streptococcus, Enterococcus (ucUTI)

Gram -ve: pseudomonas

Moxifloxacin:
Atypicals
Gram +ve: MRSA, MSSA, Streptococcus pneumonia
Gram -ve: Bacteroides

21
Q

Co trimoxazole spectrum

A

Gram +ve: MRSA, MSSA, Streptococcus pneumoniae

Gram -ve: H. Influenzae, EKP, ESBL, Enterobacter, Moraxella

22
Q

Nitrofurantoin spectrum

A

Gram +ve: enterococci
Gram -ve: E. Coli

(EE)

23
Q

Metronidazole spectrum

A

Anti protozoa: Entamoeba histolytica, Trichomonas vaginalis, Giardia lamblia

Anaerobes: Peptostreptococcus, clostridiodes, bacteroides, H. Pylori