PQ : 2.9 + 2.10 - Proteins & Enzymes

Question 1

Answer 1

Question 2

Explain why this mutation affects the function of the haemoglobin molecule.

Answer 2

Question 3

Answer 3

Question 4

State why enzymes are described as biological catalysts

Answer 4

Question 5

(i) Explain how a single base mutation can lead to an altered primary structure of enzyme G. (3)

Answer 5

Question 6

(ii) Explain how human genome sequencing can be used to identify the mutations associated with MPS I.

Answer 6

Question 7

Answer 7

Question 8

Answer 8

-Folded into a specific shape with a globular head -That can bind to actin -Myosin has a site that can bind with ATP -part is straight to form a bundle with other myosin molecules

Question 9

Muscle cells contain globular and fibrous proteins.
Compare and contrast the molecular structures of globular and fibrous proteins.

Answer 9

Question 11

Describe how a peptide bond is formed (2).

Answer 11

Question 12

The stinger injects a venom that contains the enzyme phospholipase.
This enzyme hydrolyses phospholipids, releasing fatty acids.
Describe how the structure of phospholipase allows it to hydrolyse phospholipids.

Answer 12

Question 13

Cells in people with these diseases produce incorrectly folded enzyme molecules.
Explain why enzymes that are incorrectly folded cannot carry out their function.
(3)

Answer 13

Question 14

Answer 14