PPO2 Flashcards
ARCUS
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
STROMA
60% (40-60), 90% (70-90)
No mgmt
Abnormals - serum lipid profile (young/thick)
LIMBAL GIRDLE OF VOGT
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
SUB EPI collagen (UV)
60% (40-60), 90% (70-90)
No mgmt
HUDSON-STAHLI LINE
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
BOWMAN’S
20% (20’s), 60% (60’s)
No mgmt
DECEMET’S STRIAE
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
DESCEMETS
Normal unless large - (+) pachymmetry stromal edema
No mgmt
MOSAIC SHAGREEN
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
STROMA
Normal unless trauma - (+) pachymmetry stromal edema
No mgmt
HASSAL HENLE BODIES + GUTTATA
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
Henle - peripheral, Guttata - central
Raised bits of DECEMETS into endothelium, stroma
70% (40’s)
No mgmt unless pigment, edema, fuchs - (+) pachymmetry stromal edema
CORNEAL FARINATA
Type, Layer, Prevalence, Mgmt
Degeneration
STROMA lipofusin
Normal bproduct of age
No mgmt
SALZMANN’S NODULAR DEGEN
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
Rare ~old keratitis, mucopolysaccharides, osteoporosis, pterygium
Plaque between EPITHELIUM + BOWMAN’s
Mgmt:
monitor yearly, if (+) epithelial breakdown:
rewetting drops, mytomycin C, PTK
BAND KERATOPATHY
Type, Mechanism, Layer, Prevalence, Mgmt
Degeneration
Gray calcium/phosphate salts 3/9oclock
STROMA
Normal in elderly, unless longstanding inflamm/glaucoma/hyperPTH/RA/vit D toxicity
No mgmt unless above:
serum Ca/Mg levels, Uric acid (gout), N2, Creatinine, ACE (sarcoid)
Va affected = chelating agent + scraping
DELLEN
Type, Mechanism, Layer, Prevalence, Mgmt
Rare Finding
Thinning cornea next to raised area
STROMA
Mgmt: TREAT to prevent scar/neo, remove cause, lubricate
KAYSER-FLEISCHER RING
Rare finding - WILSON’S D+ copper ring
DECEMETS
Mgmt: REFER to internist, low Cu+ diet
Kayser-Fleisher Ring
Rare finding - WILSON’S D+ copper ring
DECEMETS
Mgmt: REFER to internist, low Cu+ diet
PANNUS
Normal finding in small amounts Limbal vessels 1-2mm (micro), 2< (gross) Mgmt: FIND CAUSE micro - conj, staph bleh, CL wear, acne roseaca gross - (+) trachopa, atopic keratoconj
POSTERIOR EMBRYOTOXIN
Congenital finding, Rare = glaucoma
DESCEMETS (Schwalbe’s line)
Mgmt: DDX GLAUCOMA
IOP, gonio, iris/corneal changes
KRUCKENBERG SPINDLES
Abnormal finding
ENDOTHELIUM
Mgmt: DDX GLAUCOMA
IOP, gonio, iris transillumination, PXE/PDS
VORTEX KERATOPATHY
Other finding EPITHELIAL+STROMA Mgmt: Drugs (plaquenil/amiodarone) = normal Fabry's D+ = abnormal - refer for enzyme replacements
FLEISCHER’S RING
Fe ring at base of cone in keratoconus
FERRY LINE
Fe ring around filtering blep
STOCKER’S LINE
Fe at the head of pterygium
COAT’S RING
Fe around FB
AXENFELD LOOPS
loop of nerve from anterior ciliary body ~12% eyes
OCULARMELANOSIS
extra pigment in the eye
EPICAPSULAR STARS
remnant of TUNICA VASCULOS LENTIS. star shaped distn of brown flecks on anterior capsule
Y SUTURE
anterior Y, posterior flipped
ZONULAR OPACITIES
embryonic opacity affecting only innermost lens
CORNEAL SCAR
injruy to Bowman’s/Stroma
CORNEAL SCAR
injruy to Bowman’s/Stroma
3 types of corneal dystrophies
keratoconus, fuch’s dystrophy, epithelial/BM disorders
3 Hallmarks of Keratoconnus
irregular astigmatism, apical protrusion, paracentral stromal thinning
Munson’s sign
keratoconus - convexivity of lower lid on downgaze
Fleischer’s ring
keratoconus - Fe at base of cone
Vogt’s striae
keratoconus - vertical striae posterior stroma
Corneal hydrops
keratoconus - due to breaks in decemets membrane. Decrease vision, cause pain, edema in stroma. T(X) cycloplegics + hypertonics
Mechanism of keratoconus?
- unable to eliminate ROS/NO- = oxidative damage
- poor collagen x-linking = Bowman’s fibrillates
- causes epi to be in contact with stroma
T(X) keratoconus?
glasses
rgp’s, scleral CL’s, piggyback lenses*
corneal x-linking (riboflavin + UV)*
keratoplasty (transplant)
Prevalence of Fuch’s Epithelial Endothelial dystrophy?
Autosomal dominant, slow progression, bilateral, females
Ocular signs of Fuch’s dystrophy?
Early - guttata: change sin endo due to dec ability to act as a pump
Progression - stromal edema, corneal scarring, epithelial edema, bullous keratopathy
Complications of Fuch’s?
2˚ glaucoma - same mechanism that destroys endo prob destroys trabecular meshwork
T(X) fuch’s?
Hairdryer in morning
5% NaCl hypertonic drops, ointment at night
BCL’s
PTK for corneal scarring
Decemet stripping automated endothelial keratoplasty (DSAEK) in severe cases
Prevalence of Epithelial BM dystrophy
40’s to 70’s, women
Causes of epithelial BM dystrophy?
Problems with the BM: thickening causes Epi to unadhere from stroma = melformed hemidesmosome connections
4 ocular findings of epithelial BM dystrophy?
dots (microcysts in epithelium)
fingerprints (projections of BM into epi)
maps (thick BM overlying epi)
blebs (mounts of granular tissue bw bowman’s + BM)
best way to view findings of epithalial BM dystrophy?
direct retro for opacifications in corneal epithelium and BM!
Complications of epithelial basement membrane dystrophy?
Increase chance of erosion
Epithelial BM Dystrophy T(X)
No S(X) = monitor DE = lubricate Erosions = ointment, pressure patch, NaCl- agents PTL on Bowman's to help healing
Loss of Corneal claricity is caused by 4 things
NISE
neo, injury, scarring, edema
How long for epithlium to regen?
24-48 hrs, total cycle is 7-14 days
How long for BM to regen?
6-8 days
Where does neo happen = loss of claricity
Surface + Stroma
Diff between surface + stromal neo?
Superficial neo - tight CL’s, trachoma, superior limbal keratitis
Deep stromal neo - infection, usually Syphilis, TB, mumps, interstitial keratitis
5 symptoms of corneal injury
PPHVL Pain Photophobia Halos dec VA Lacrimation
Causes of corneal injury
abrasion, bullous keratopathy, trauma
DDx Ulcer vs Abrasion
Ulcer = (+) history, pain, wbc’s, epithelium and stroma, takes up NaFl
Abrasion = epithlium, NaFl stays in would, red, no discharge
How do you T(x) a corneal abrasion?
antibiotics + cycloplegia
How do you treat a recurrent corneal erosion?
pressure patch, scrape epi to improve healing, BCL
How do you treat a FB in the cornea?
irrigate, alger brush, then treat as if abrasion (lub, BCL’s, antibiotics, cyclo)
Explain epithelial edema
Cause: PMMA’s, rbcs,abrasion, swimming, scatters light >5%
Sign: sclerotic scatter = dark
S(X): dec VA, halos, spec blur
Mgmt: hypertonic NaCl, hair dryer, lower IOP, remove cause
Explain stromal edema
Cause: Soft CL’s, Fuch’s, surgical, trauma, ulcers, IOP, glaucoma
S(X): glare
Mgmt: pachymetry, DSAEK, steroids
8 layers of the lid
eyelashes, skin, vasculature, muscles, grey line, orbital septum, tarsal plate, conjunctiva
Glands in the eyelashes
glands of moll (sweat), glands of zeiss (sebaceous)
innervation to eyelid
orbicularis oculi (CN7) - close shut
muellers (SNS) - tonic elevation
levator (CN3) - open
Where are the glands of moll?
eyelashes
Where are the glands of zeiss?
eyelashes
where are the meibomian glands?
tarsal plate
Components of anterior lid
eyelashes, skin, vasculature, muscles, grey line
components of posterior lid
tarsal plate, conjunctiva