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BNF > PPIs > Flashcards

PPIs Flashcards

1
Q

What are the main indications of PPIs?

A 
Gastric and duodenal ulcers
Eradicating H. pylori
dyspepsia
GORD
Prevention of NSAID associated ulcers
In CF with pancreatic enzyme supplements (reduces degradation of the enzymes)
Zollinger-Ellison syndrome (excess acid)
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2
Q

What are the main cautions with PPIs?

A

Can mask gastric cancer symptoms
Can increase risk of osteoporosis
Can contribute to hypomagnesaemia
Can increase risk of C. diff

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3
Q

What are the most common side effects of PPIs?

A

GI - N, V, D, C, abdo pain, flatulence

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4
Q

Can PPIs be used in hepatic impairment?

A

Reduce dose

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5
Q

Can PPIs be used in renal impairment?

A

Not stated, or caution

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BNF (2 decks)

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