PPI Flashcards
(20 cards)
Omnigenic traits
idea that any regulatory gene variant in a specific tissue is likely to have weak effects on multiple traits or diseases influenced by that tissue.
Network Pleiotropy
single genetic variant may affect multiple traits, not because they are directly connected, but because they are mediated through same cell types, or regulated through same networks.
Extreme Pleiotropy
Single genetic variance or set, influence multiple, seemingly unrelated traits or processes.
Difference between Omnignenic Traits and Network Pleiotropy
OT (equifinality) - many genes influencing one trait; NP (multifinality) interconnected effect of single variant on multiple traits.
Extreme Pleiotropy vs. Network
Both (multifinality) - Network highlights pathways, Extreme highlights rage of traits affected.
Goals
Cognitive Representations of end states interconnected to means of attainment.
Self-Regulation
Process by which people set goals and attempt to attain them
Successful self-regulation
acting in accordance with ones goals
Goal activation
Selection of actions and resource mobilization towards goal advancement
Transfer of affect
Behavior that may initially be neutral/ aversive become desirable in the absence of original motivation
Goal-conflict resolution
Goal representations activate at the same time, leading individuals to seek multifinal means of satisfying multiple goals simultaneously
Goal shielding
People inhibit weaker alternatives in favor of prioritized goals
Motivated Distortion
Result of goal shielding; Active distortion of information relevant to goal pursuit to align with current motivational state.
Attentional Bias
momentarily heightened accessibility to drug leads to inhibition of alternative concens.
Big 5
Emotional stability; Extraversion; Openness; Agreeableness; Consciousness
Rich get richer hypothesis
people who are sociable and have strong relationships, high self esteem and low social anxiety show most benefit of internet use
Compulsive Internet Use
Continued use despite intention to stop; internet dominates cognition and behaviors; Withdrawal - unpleasant emotions when internet use is not possible; using internet to escape from negative feelings; conflicts arise due to internet use.
Prosocial behavior
Any voluntary act meant to benefit another
Behavioral Coherence/ Heterotypic continuity
continuity of an inferred trait that is presumed to underlie diverse phenotypic behaviors
