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biochem 2 > Powerpoint 1 > Flashcards

Powerpoint 1 Flashcards

1
Q

What is the letter code for amino acid Aspartic Acid? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: D; Polar; Negative Charge

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2
Q

What is the letter code for amino acid Glutamic acid? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: E; Polar; Negative

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3
Q

What is the letter code for amino acid Arginine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: R; Polar; Positive charge

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4
Q

What is the letter code for amino acid Lysine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: K; Polar; Positive charge

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5
Q

What is the letter code for amino acid Histidine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: H; Polar; Positive Charge

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6
Q

What is the letter code for amino acid Asparagine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: N; Polar; Uncharged Polar

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7
Q

What is the letter code for amino acid Glutamine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: Q; Polar; Uncharged polar

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8
Q

What is the letter code for amino acid Serine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: S; Polar; Uncharged Polar

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9
Q

What is the letter code for amino acid Threonine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: T; Polar; Uncharged Polar

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10
Q

What is the letter code for amino acid Tyrosine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: Y; Polar; Uncharged Polar

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11
Q

What is the letter code for amino acid Alanine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: A; Non polar; non polar

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12
Q

What is the letter code for amino acid Glycine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: G; Non polar; non polar

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13
Q

What is the letter code for amino acid Valine Acid? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: V; non polar; non polar

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14
Q

What is the letter code for amino acid Leucine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: L; non polar; non polar

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15
Q

What is the letter code for amino acid Isoleucine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: I; non polar; non polar

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16
Q

What is the letter code for amino acid Proline? Polar or nonpolar? and what is the charge on the side chain?

A

Letter Code: P; Non polar; non polar

17
Q

What is the letter code for amino acid Phenylalanine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: F; non polar; non polar

18
Q

What is the letter code for amino acid Methionine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: M; Non polar; non polar

19
Q

What is the letter code for amino acid Tryptophan Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: W; non polar; non polar

20
Q

What is the letter code for amino acid Cysteine? Polar or nonpolar? and what is the charge on the side chain?

A

Letter code: C; non polar; non polar

21
Q

How are disulfide bonds formed?

A

Between cysteines in the same protein or different polypeptide chains

22
Q

Draw Cysteine

A

5 carbons, HS left, OH right, O double bond right, NH2 thick

23
Q

what types of proteins contain alpha helices?

A

cell membrane proteins; consists largely of amino acids with nonpolar side chains

24
Q

what are the 3 amino acids in the hydroxyl group?

A

S,Y,T
Serine, Tyrosine, Threonine

25
Q

alpha helix 3 main facts

A

3.6 amino acids; hydrogen on every 4th peptide bond; hydrogen runs parallel

26
Q

Which amino acids is used to form disulfide bonds?

A

Cysteine

27
Q

What is PDI and what does it stand for?

A

Protein disulfide isomerase and it’s responsible for forming disulfide bonds

28
Q

what do alpha helices: Coiled Coil do? when do they form?

A

forms very stable structures called coiled coil. forms when 2 or 3 alpha helixes have most of their nonpolar side chains on one side

29
Q

structure of a coiled coil:

A

labeled as sevenfold sequence “abcdefg”
Hydrophobic aa’s “a” and “d”

30
Q

what destabilizes alpha helices?

A

electrostatic repulsion between similarly charged R groups

31
Q

which amino acid is incompatible with alpha helix?

A

Proline

32
Q

B-pleated sheets. what about the hydrogen bonds

A

hydrogen bonds are perpendicular

33
Q

what is motifs?

A

repeated combinations of supersecondary structure with a protein

34
Q

what is a domain aka module?

A

a specific region of a protein that can fold independently into a discrete stable structure and has its own function

35
Q

what is domain shuffling?

A

DNA sequences encoding each domain accidentally becoming joined, creating a new gene

biochem 2 (1 decks)

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