power Flashcards

1
Q

What is statistical power?

A

Statistical power is the probability of correctly rejecting the null hypothesis when it is false, i.e., detecting an effect when one truly exists.

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2
Q

How is statistical power mathematically defined?

A

Statistical power = 1 − Type II error (𝛽)

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3
Q

Why is statistical power important in study planning?

A

It helps determine the required sample size to detect a given effect or the smallest effect detectable with a given sample size.

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4
Q

What factors influence statistical power? (4)

A

Sample size
effect size
variability in the system
the significance level (𝛼).

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5
Q

What is a Type I error?

A

A Type I error (false positive) occurs when the null hypothesis is incorrectly rejected.

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6
Q

What is a Type II error?

A

A Type II error (false negative) occurs when the null hypothesis is not rejected despite being false.

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7
Q

What is the significance level (𝛼) in hypothesis testing?

A

The probability of making a Type I error, commonly set at 0.05 (5%).

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8
Q

How is statistical power related to Type II errors?

A

Higher power means a lower probability of Type II errors (𝛽), reducing the risk of failing to detect a true effect.

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9
Q

What is the null hypothesis (𝐻0) in hypothesis testing?

A

The assumption that there is no effect or difference in the population being studied.

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10
Q

What is an alternative hypothesis (𝐻1)?

A

The hypothesis that there is a real effect or difference in the population.

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11
Q

How does sample size affect statistical power?

A

Larger sample sizes generally increase power, making it easier to detect true effects.

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12
Q

How does effect size impact power?

A

Larger effect sizes make it easier to detect differences, increasing power.

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13
Q

What is the formula for the test statistic in a one-sample z-test?

A

Zstat = (data estimate - hypothesised value)/standard error

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14
Q

In a hypothesis test, when do we reject 𝐻0?

A

When the test statistic exceeds the critical value (𝑧𝑐𝑟𝑖𝑡) based on the significance level (𝛼).

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15
Q

What are the main ways to increase statistical power?

A

Increase sample size, reduce variability, accept a higher Type I error rate, or detect a larger effect size.

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16
Q

How does increasing sample size affect power?

A

Larger sample sizes reduce the standard error, making it easier to detect true effects and increasing power.

17
Q

How does reducing variability increase power?

A

Controlling variability (e.g., testing under standard conditions) reduces noise in the data, making effects easier to detect.

18
Q

How does accepting a higher Type I error rate (𝛼) affect power?

A

A higher 𝛼 lowers the decision boundary, reducing Type II error and increasing power.

19
Q

What is the trade-off when increasing power by raising 𝛼?

A

It reduces Type II errors but increases the likelihood of false positives (Type I errors).

20
Q

What is the advantage of using simulations to estimate power?

A

Simulations provide an intuitive and flexible way to estimate power, especially for complex designs.

21
Q

How does simulation-based power estimation work?

A

Generate many random samples under 𝐻1, compute test statistics, and estimate power based on rejection rates.

22
Q

What happens to Type I and Type II errors when adjusting for multiple comparisons?

A

Decreasing Type I error (false positives) increases Type II error (false negatives), reducing power.

23
Q

How does adjusting the family-wise error rate (FWER) affect power?

A

It makes Type I error thresholds more stringent, increasing the likelihood of Type II errors and lowering power.

24
Q

Why is power important in planning a statistical study?

A

It ensures a high probability of detecting a real effect if one exists, reducing the risk of false negatives.

25
Q

What is the commonly accepted minimum power level for a study?

A

80%, meaning there is a 20% chance of failing to detect a true effect.

26
Q

What factors decrease statistical power?

A

Small sample sizes, small effect sizes, and high variability in measurements.

27
Q

Why is post-hoc power analysis considered meaningless?

A

If 𝐻0 is not rejected, power will always be low by definition, making post-hoc calculations misleading.

28
Q

What is the problem with conducting a post-hoc power analysis after failing to reject 𝐻0?

A

It falsely suggests that low power justifies a negative result, which is statistically invalid.

29
Q

What is an example of scientific misconduct related to power?

A

Designing a study with low power to deliberately fail to reject 𝐻0.