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DDS LAB (Ma'am Shanny) > POWDERS > Flashcards

POWDERS Flashcards

1
Q

It is dry finely divided drugs &/
or chemicals

A

POWDERS

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2
Q

taken orally after mixing with water

A

INTERNAL USE:

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3
Q

inhaled for local effects or systemic effect
(analgesic)

A

INTERNAL USE:

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4
Q

intended for internal (oral
powder) or external use
(topical powder)

A

POWDERS

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5
Q

intimate mixtures of drugs

A

POWDERS

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6
Q

Advantage of medicated powders
-F

A

Faster rate of dissolution & absorption/rapid
therapeutic effect

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7
Q

Advantage of medicated powders
-s

A

More stable than liquid

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8
Q

Advantage of medicated powders
-con

A

More convenient to swallow than tablet
or capsules

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9
Q

Disadvantage of medicated powders
-t

A

Can’t mask undesirable taste

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10
Q

Disadvantage of medicated powders
-inc0

A
  • Inconvenient to carry
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11
Q

Disadvantage of medicated powders
-p

A

Difficulty of protecting from
decomposition (hygroscopic,
deliquescent or aromatic
materials)

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12
Q

Disadvantage of medicated powders
-i

A

Inaccuracy in dose

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13
Q

production method for levothyroxine sodium

A

Comminution/Particle size
reduction

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14
Q

Extemporaneous aka

A

Small scale

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15
Q

Mills & pulverizers

A

large scale

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16
Q

reducing the particle size of solid
(comminution) before mixing with other
components, further processing, or
incorporation into a final product

A

mixing

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17
Q

movement of spatula on a sheet of paper/ointment
tile

A

Spatulation

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18
Q
  • to comminute and to mix powders.
A

Trituration

19
Q

not suitable for large quantities of powders or powders
containing potent substances.

A

Spatulation

20
Q
  • suited to mixing solid substances that form eutectic
    mixtures
A

spatulation

21
Q

used when a small amount of potent substance is mixed with
a large amount of diluent

A

Geometric dilution method

22
Q

ensure the uniform distribution of the potent drug.

A

Geometric dilution method

23
Q

Geometric dilution method

A

trituration

24
Q

powders mixed by passing through the sifters - results
in light, fluffy product.

A

sifting

25
Q

use of a machine / motorized equipment (for industrial
purposes).
- time consuming

A

tumbling

26
Q
  • not acceptable for incorporation of potent drugs into a
    diluent powder.
A

sifting

27
Q

Methods for the determination
of particle size

A

L,S,S,M,L,C

28
Q

memonics for the determinationof particle size.

L,S,S,M,L,C

A

◼ Sieving
◼ Microscopy
◼ Sedimentation rate
◼ Light scattering
◼ Laser holography
◼ Cascade impaction

29
Q

Particles passed by mechanical shaking through
a series of sieves (

A

sieving

30
Q

very coarse is no.?

A

8

31
Q

coarse is no.?

A

20

32
Q

moderately coarse is no.?

A

40

33
Q

very fine sieve is no.?

A

80

34
Q

fine sieve is no.?

A

60

35
Q

Particles are sized through the use of a calibrated
grid back ground

A

microscopy

36
Q

Particle size is determined by measuring the terminal
settling velocity of particles through a liquid medium in
a gravitational or centrifugal environment

A

sedimentation rate

37
Q

this method of determination is calculated using stoke’s law

A

sedimentation rate

38
Q

Pulsed laser is fired through an aerosolized particle spray and
photographed in three dimensions with a holographic camera,

A

LASER HALOGRAPHY

39
Q

Driven by an airstreams will hit a surface in its
path, provided that its inertia is sufficient to
overcome the drag force that tends to keep in
the airstreams.

A

Cascade Impaction

40
Q

purpose of particle size analysis in pharmacy:

A

to obtain quantitative data of drug and other components used in pharmaceutical formulations on the
size
distribution
shape

41
Q

divided aka

A

chartulae

42
Q

packaging material used

A

*Simple bond paper
*Vegetable parchment
*Glassine
*Waxed paper

43
Q
A

DDS LAB (Ma'am Shanny) (2 decks)

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