Postnatal and child development Flashcards
Transition from prenatal to postnatal: 4 systems + pre/post differences
- EndocrinePre: IGF2 → 1Post: Human growth hormones hGH
- GeneticsPre: minor effec, maternal factors overridePost: determines final height
- NutritionPre: PlacentaPost: Nutritional abnomalities (Obesity, malabsorption)
- Environment
4 phases of growth
- fetal
- infantile
- childhood
- pubertal
General notes on head
head is larger thna body and sutures close at 18 months
Which 2 phases have 30% growth
fetal
What causes growth levels in infntile/childhood
nutrition levels
What causes growth levels in pubertal
Sex hormones
What’s antagonistic with sex hormone development
self-limiting as sex hormones fuse grwoth plates (stopping growth)
What phase has 15% of growth?
infantile and pubertal
What phase has the majority of growth
Childhood (40%)
What is mini puberty
Increase in HPG Axis activity as a neonate
Theory Reason for this mini puberty - increasing HPG axis
elevated maternal HPG inhbiits fetal HPG, so after birth this increases in activity transiently
3 changes that mini puberty might cause in neonates
- sex steroids can cause gonadal dev (testicular tissue)
- High testosterone in boys may explain higher growth velocity → Sertoli tissues do not have an androgen receptor yet so no spermatogenesis.
- In females, it may be important in patterning and dev of breast tissue
What triggers puberty?
- heory: nuerokinin nuerones regulate release of kisspeptin acts on GnRH.
- mutations in KISS affect puberty timing
Development milestone at the right timing is called…
consonance
4 developmental domain
- Gross motor development
- Sensory and fine motor dev
- Social behaviour
- Hearing, speech and language
Gross motor development:How do newborn babies look when lying flat?
limited flex
At 6-8 weeks how well can babies raise their head? GM
head rasied 45 degrees
What happens at 6-8 months?GM
6 month: sit up- curved back
8 month: sit up straight
What about 10 months? GM
Stand up and cruise around furniture
What can babies do by 8-9 months?GM
Crawl around
12 months: GM
walk unsteady
GM 15 months?
walk steady