Postganglionic Parasympathetic Transmission Flashcards
Muscarinic Antagonist
Atropine
Cholinesterase inhibitor- inhibits transport of choline transporter
Neostigmine
Block voltage gated ca2+ channels
Dihydropyridine
Block vesicle fusion
Botulinum toxins
Block Ach activated channel
Hexamethoneum
Non-depolarising nicotinic receptors
Mecylamine
Depolarising nicotinic receptor blockers
Suxamethoneum
Muscarinic receptor antagonist
Atropine
Muscarinic receptor agonist
Carbachol, pilocarpine
Block enzymes that produce NA
Carbidopa
Block transporter of NA
Resperpine
Introduce a false transmitter and activate alpha 2 receptors
Methyldopa
Block alpha or beta postsynaptic receptors
Doxazosin or propranol
Stimulate NA release
Amphetamine
Inhibit uptake into neurones
Cocaine & tricyclic depressants