Post Transcriptional Modifications

Question 1

Phosphorylation

Answer 1

Addition of phosphate to increase energy level

Question 2

Nitrosylation

Answer 2

Addition of Nitrosyl groups. Occurs on Cysteine

Question 3

Lipidation/Acylation

Answer 3

Addition of a lipid. Regulates protein function. Occurs on Cysteine

Question 4

Hydroxylation

Answer 4

Addition of OH- to Increase protein solubility in water

Question 5

Glycosylation

Answer 5

Addition of a Sugar chain. Important for communication and secretory proteins

Question 6

Acetylation and Methylation

Answer 6

Changes protein conformation, important for regulation of transcription. Addition of an acetyl or methyl group