Porcine reproductive disease Flashcards

1
Q

Key Targets

A
  • Indoor pigs are more productive than outdoors
  • Aim for 88% farrowing rate
    • % of sows served that go on to successfully farrow
  • 5% regular return
  • 2% irregular return
  • <1% abortion
  • <1% endometritis
  • 1% NIP (not in pig)
  • 1% death
  • Intervention level for stillbirths is 7%. If higher than this, need to do something about it.*
  • Usually due to management shortcomings as the pig is INCREDIBLY fertile.*
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2
Q

Postweaning management

A
  • After weaning, boar contact from day 1 is essential = LH pulsatility, contact must stop the day before service.
  • Service should be intensive, twice a day.
  • Best if sows are bought to the boar
  • Apply back-pressure test
  • Continuous contact the with the boar is NOT desirable - habituation
  • Sows on ad-lib lactator diet
  • Day length is important in service house:
    • 16 hours of light, 200 lux (blue light best) - needs to be like this 365 days a year.
  • Wean-to-service interval = 5 days!

Sows should be served 24 hours after onset of standing heat. Gilts should be served 8-12 hours.

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3
Q

Inseminations

A
  • Minimum of 2 inseminations
    • 24 hour intervals (sows) e.g. mon morning and tues morn
    • 12 hour intervals (gilts)

Sows usually need to be moved <5 days after insemination, OR not until 35 days else will interfere with implantation.

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4
Q

Semen vs Egg

A
  • Semen has a long way to travel
  • survives 48 hours in uterus
  • Capacitation after 4-6 hours
  • Eggs are only viable for 8-12 hours
  • semen therefore needs to be waiting for the egg - this is why we do the first service.
  • service timing is crucial
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5
Q

Fertility management

A
  • Feeding in lactation important - excessive weight loss leads to longer W-S interval and lower numbers born
  • 26-28 day lactation
  • BCS is the most common reason for extended W-S interval. Aim is to lose only 0.5 during lactation.*
  • Most sows should be 2.5-3.0 at weaning.*
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6
Q

Lactation feeding

A
  • Feed increased for last 3 weeks of gestation, but feed is reduced on entry to farrowing accomodation
  • Sows increased 7-10 days over lactation to maximum feed intake
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7
Q

Gilt reproductive targets

A
  • Puberty by 180-210 days of age (6 months) - boar contact from 180d
  • Mated by 235-255 days at 135-150kg live-weight
  • Mated at 2nd or 3rd recorded heat (first heat have poor quality embryo and few born alive)
  • Farrowing rate +5%, bettwe than sow average
  • successfully re-breed within 6 days of weaning.

Gilts only stop being gilts when served a second time.

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8
Q

Factors that affect oestrus

A
  • Progestagen synchronisation
  • Altresyn/Regumate (progesterone)
  • Dosed 5ml orally for 18 days - same time each day
  • Oestrus around 5 days later
  • Very common in batch farrowing
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9
Q

Seasonal Infertility

A
  • Autumn infertility - spring breeders (happy to get pregnant from Christmas onwards)
  • During autumn, not cycling, increased returns, abortions
  • caused by short days, variation in day night temps
  • natural phenomenon in the pig

BE PREPARED:

  • increased feed level 0.25-0.5kg/sow/day
  • increase boar contact 30-60 min/day
  • avoid chilling
  • There is also a summer infertility - heat stress and sunburn. Outdoor herds need to have water wallows.*
    • Pigs are sensitive to sunburn, produces prostaglandins and this causes reduced fertility.*
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10
Q

Poor fertility and infectious disease

A
  • Sows or boars off-feed, pyrexic
  • abortions/ mummified foetuses
  • irregular return to heat
  • weak/premature piglets
  • viruses are most common infectious cause of repro failure in pigs
  • PRRSv - MOST IMPORTANT
  • Swine influenza
  • SMEDI (not common)
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11
Q

Porcine Reproductive and Respiratory Syndrome Virus (PRRSv)

A
  • Blue Ear Disease (septicaemia)
  • Spread by movement of carrier pigs (airborne) - genotype 1 (Europe)
  • Invades and kills macrophages
  • Many herds endemically affected
  • Genetic mutation common - new strains
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12
Q

Disease status PRRSv (3)

A

Negative:

  • Biosecurity key - strong perimeter, no unauthorised visitors unless disinfected. Check status maintained with serology.
  • Risks - stock, people, vehicles, airborne

Positive, stable:

  • THIS IS THE MOST COMMON
  • serologically +ve, but not shedding
  • piglets weaned -ve virus
  • achieved with VACCINATION

Positive, unstable:

  • serologically +ve and shedding
  • piglets weaned virus +ve
  • sows might be immunocompromised
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13
Q

PRRSv replacement strategy

A
  • PRRS -ve
    • buy -ve replacements
    • quarantine min 8 weeks and check after 5 weeks
    • strict biosecurity
    • home breed
  • PRRS +ve
    • Isolate and vaccinate replacements
    • VACCINATION
    • do not serve gilts until >6 weeks since infection/vaccination
    • Buy negative replacement stock
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14
Q

Control of PRRSv

A
  • Monitoring the positive herd
  • PCR - oral fluids, blood, tissue
    • Blood - pin prick ear in 30x piglets at weaning, aborted sows, PCR
    • Tissue
      • foetal thymus
      • spleen
      • lung

Vaccination is the mainstay!

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15
Q

Swine Influenza

A
  • Causes poor fertility due to pyrexia
  • Included in investigation for high pregnancy failure rates
  • H1N1, H1N2, H3N2 most common
  • Introduced by people, carrier pigs, birds
  • Diagnosis:
    • clinical signs, nasal swabs, serology
  • Control:
    • ​biosecurity
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16
Q

SMEDI

A
  • Stillbirth, Mummification, Embryonic Death, Infertility - not common
  • CAUSES:​​
  1. Parvovirus (PPV)
  2. Teschoviruses (sapelovirus, teschen, talfan)
  3. Encephalomyocarditis virus (EMCV)
  4. PCV 2

Transplacental infection of foetus. Abortion is rate, foetuses usually fo to term as no prostaglandin trigger.

17
Q

Porcine Parvovirus (PPV)

A
  • Common and important
  • survives well outside
  • sows develop life-long immunity, so clincial dx usually in gilts
  • if infected <35 days gestation - return to service - cycle length is 21 days.
  • if infected 35-70 days gestation - death of piglets and mummification
  • if infected 70 days +ve - weak piglets/ stillbirths

DIAGNOSIS - foetal serology and PCR

Control:

  • Rare due to vaccination
  • VACCINATE every parity/every other parity
  • Can combine vaccination with erysipelas
18
Q

Teschoviruses

A
  • Formerly enteroviruses
  • serotypes 1,3,6 and 8 cause repro dx
  • Faeco-oral transmission
  • DIAGNOSIS:
    • ​serology and virus isolation
  • CONTROL:

control exposure to faeces to immunise gilts/ sows at least 6 weeks prior to breeding

19
Q

Encephalomyocarditis virus (EMCV)

A
  • Main reservoir is rats
  • Type A causes reproductive dx, type B causes heart failure
  • Clinical dx when there is a high prevalence of rats
  • Diagnosis: Serology, PCR
  • Control: incoming stock, vermin control
20
Q

Porcine circovirus 2 (PCV 2)

A
  • causes heart muscle damage in developing foetus
  • Diagnosis: fetal myocarditis and immunohistohemistry
  • control: vaccination of gilts pre-breeding
21
Q

OTHER VIRUSES;

AUJESKY’S DX

A
  • Pseudorabies virus, herpes
  • no clinical signs in the sow
  • abortions seen, neurological signs in newborn piglets
  • signs milder as age increases
  • not currently in UK
  • NOTIFIABLE
22
Q

Classical swine fever (CSF)

A
  • Pestivirus, similar to BVD
  • Important cause of congenital tremor (type A1)
  • abortion may occur at any stage
  • spread by pigs eating infected pigs or their faeces of fluids
  • not currently in the UK
23
Q

African Swine Fever

A
  • Deoxivirus
  • pyrexia, anorexia, lethargy, sudden death, abortions, still births, weak litters
  • very similar to CSF
  • never been a case in the UK
24
Q

Bacterial causes of repro failure:

A
  1. Leptospirosis
  2. Erysipelas
  3. Brucella suis
  4. Chlamydophila
  5. Toxoplasma gondii
25
Q

Leptospirosis

A
  • L. pomona, L. tarassovi and L. bratisalva/muenchen
  • Clinical signs:
    • abortions/ stillbirths, vaginal discharge
  • Diagnosis:
    • ​serology in returning sows
    • foetal tissues (FAT)
  • Treatment:
    • ​antibiotics - tetracyclines
  • control:
    • ​vaccination, use of AI, control rodents, hygiene in service area
26
Q

Erysipelas

A
  • E. rhysiopathiae
  • excreted in saliva, faeces and urine
  • zoonotic potential (rare)!
  • aortions, mummified foetuses, returns
  • DIAMOND lesions on skin
  • diagnosis- difficult
  • treatment - sensitive to penicillin
  • control - vaccination!
27
Q

Brucella suis

A
  • Not in the UK
  • Carried by European hare, but never been found in this species in the UK
  • causes infertility, abortion and weak piglets, can also cause abscesses
  • serological cross reactions with Yersinia enterocolitica can be problematic!
28
Q

Endometrial and Vulval discharge syndrome

A
  • Discharge 14-21days post-service
  • ‘Normal’ up to 2 days post-service
  • May cause reduced fertility
  • Diagnosis: observation and records
  • Control: cull affected sows, service management

To do with bacteria and hygiene.

29
Q

Notifiable diseases causing repro failure

A
  1. Brucella suis
  2. Aujesky’s Disease
  3. CSF
  4. ASF
30
Q
A
31
Q

Anoestrus

A
  • Rarely true anoestrus, usually increased W-S interval
  • Related to sub-optimal nutrition during lactation
  • Rarely failure to recognise oestrus - rule out
  • Gilts:
    • group management, health and nutrition, acclimitisation, boar contact, light, housing
  • Sows:
    • nutrition, environmental management
32
Q

Ovulation

A
  • Variable litter size, decreased farrowing rate
  • Nutrition
  • hybrid vigour
  • good general health
  • ensure good feed intake during lactation
  • disease causing embryonic death or foetal damage later on
33
Q

Fertilisation

A
  • High rates of return, variable litter size
  • accurate oestrus detection
  • served at correct time
  • nutrition
  • group changes after service
  • boar management if natural service
  • disease
34
Q

Implantation

A
  • Occurs 14-17 days after ovulation
  • Irregular returns (25-35 days), small litter sizes
    • nutrition
    • boar contact for >28 days post-service
    • 16 hrs light
    • stress 2-25 days post-service
    • general sow health
35
Q

Foetal death/abortion

A
  • If embryo dies <35 days, resorption and return to service ~63d
  • If embryo present after 35 days, mummification
  • Crown-rump indicates age of death.
  • If large number of piglets healthy, then unlikely dx
  • If small number of piglets born healthy and large no. mummified, dx likely
36
Q

Stillbirth

A
  • Usually related to sow factors:
    • fat sows, prolonged farrow/dystocia
    • large litters/large piglets
    • fresh born death is usually poor supervision around farrowing
    • usually not infectious
  • In general, to investigate infectious causes, foetus samples better than sow due to vaccine complications.*
    • try to submit samples from 4-6 foetuses/litter from at least 3 litters.*
    • brain, heart, lung, liver, spleen, kidney, placenta*
37
Q

Summary

A
  • Normally reproductive failures due to management
  • Viruses more common infectious cause
  • Use data to identify ‘problem’ area e.g. fertilisation