Population Genetics Flashcards
1
Q
Define Evolution
A
Change of allele frequencies over time in populations
2
Q
What are the four processes that cause changes to allele frequencies
A
- random chance related to which alleles make it into the offspring can result in loss of alleles (genetic drift)
- Random mutations can introduce new alleles into the population, which will impact overall allele frequencies
- random individuals can join or leave the population, taking or leaving their genes/alleles with them: gene flow
- natural selection: a particular allele increases in frequency due to giving individuals in that population some kind of reproductive advantage
3
Q
Hardy-Weinberg Principle
A
makes the assumption that no change has taken place and compare our population to that
- p2 + 2pq + q2 = null hypothesis (should equal 1/ 100% of the population)
compare the numbers we get for p2, 2pq, and q2 to the experimental data from our population, and we can assess change in the population over time
4
Q
HW principle assumptions
A
- evolution is not happening (no loss or gains of alleles)
- mating is completely random
- if observed allele frequencies are calculated and do not match those calculated using the HW principle then we know that one of these assumptions has been violated.