Poop I forget

Question 1

Clinical features of PSC

Answer 1

Majority of pts are asymptomatic. Usually, fatigue and pruritic.

Question 2

Liver bx of PSC

Answer 2

Fibrous obliteration of small bile ducts with concentric replacement by connective tissue in an onion skin pattern

Question 3

Which autoimmune disease highly associated with underlying ulcerative colitis?

Answer 3

PSC

Question 4

Complications of PSC

Answer 4

Intrahepatic/extrahepatic biliary stricture. Cholangitis & cholelithiasis (cholesterol and/or pigment stones). Cholangiocarcinoma. cholestasis (e.g., fat soluble vitamins decreased, osteoporosis). Colon CA.

Question 5

Random serologic findings of PSC

Answer 5

Hypergammaglobulinemia, increased serum IgM, atypical p-anca.

Question 6

Polymyalgia rheumatica labs

Answer 6

Markedly elevatedd ESR which is often associated with anemia. CK and aldolase are usually normal.

Question 7

Treatment of polymyalgia rheumatica

Answer 7

Low dose prednisone at 10-20 mg/day.