Polymorphic VT and VF, Electrical storm and Incessant VT Flashcards
Polymorphic VT and VF that occur within ___ h of MI are associated with greater in hospital mortality
48h
but px who survive past hospital discharge are NOT at increased rusj fir arrhythmic sudden death
What could be given to acquired long QTS px who develops VT if magnesium alone is ineffective
isoproterenol
Definition of prolonged Qtc
____ in men
____ in women
> 440 ms in men
460 in women
Congenital LQTS that tend to occur during exertion particularly swimming
LQTS-1
Congenital LQTS associated with sudden auditory stimuli or emotional upset
LQTS-2
Congenital LQTS that tends to occur during sleep
LQTS-3
Most patients with LQTS 1 and 2 will respond to adequate doses of ____
beta blockers
Markers of increased risk in congenital LQTS
QTc> 500 ms
Female
Hx of syncope/ cardiac arrest
QTc of px with Short QT syndrome
< 360 ms
but is usually < 300 ms
Gene mutations associated with catecholaminergic polymorphic VT
Commonly caused by RYR2 and less commonl Calsequestrin 2
VT is often polymorphic, may be bidirectional
Use of ICD is controversial because shock could initiate vicious cycle of adrenergic output and escalated VA leading to death
Most common genetic cardiovascular disorder
HOCM
Risk factors for SCD in HOCM (6)
Young age
NSVT
Failure of BP to increase during exercise
Recent (within 6 mos) syncope
Ventricular wall thickness > 3 cm
Severity of LVOT
Genetric dilater CM accounts for ___ % of nonischemic dilated cm
30-40%
Definition of electrical storm
3 or more VT or VF within 24h requiring intervention for termination
Definition of incessant VT
VT continues to recur shortly after electrical, pharmacologic or spontaneous conversion to NSR
Typically monomorphic
