Polymer Encapsulation

Question 1

O/W emulsion technique, the polymer and drug is first dissolved in…

Answer 1

common, organic solvent

Question 2

In W/O/W emulsion technique, the polymer and drug is first dissolved in…

Answer 2

aqueous solution

Question 3

In primary W/O emulsion of double emulsion, the oil part consists of

Answer 3

polymer dissolved in water immiscible organic solvent

Question 4

The primary W/O emulsion is added to a rapidly stirring…

Answer 4

aqueous solution

Question 5

Microspheres prepared by W/O/W are characterized by

Answer 5

pores in the internal structure

Question 6

Flow Focusing

Answer 6

to get better control of over final microsphere size

Question 7

In flow focusing the disperse phase has a ____ flow rate than the continuous phase

Answer 7

lower

Question 8

steps to solvent casting

Answer 8

1. Dissolve polymer and drug in common solvent
2. Cast into molds
3. Let evaporate solvent
4. Polymer solidified in shape of mold

Question 9

Electrospinning can form drugs into

Answer 9

mats, sheets

Question 10

What method is used to form pellets, rods, wafers or discs?

Answer 10

Melt extrusion

Question 11

What type of polymer can be used in melt extrusion?

Answer 11

PLA, PLC

Question 12

Melt extrusion requires that the polymer to be

Answer 12

semicrystalline because it needs the polymer to have melting point

Question 13

Polymeric DDS that release drug via diffusion may be classified as

Answer 13

1. Matrix Type Systems

2. Reservoir Type Systems

Question 14

Explain Matrix Type Systems

Answer 14

usually made from biodegradable polymers which releases drug via diffusion

Question 15

Explain Reservoir Type Systems

Answer 15

a drug core surrounded by a polymer membrane usually made of non-degradable polymers