Polycythemia Vera Flashcards
1
Q
What are the essentials of diagnosis?
A
JAK2 mutation and splenomegaly
2
Q
Who are more affected age wise
A
The elderly
3
Q
Cut off point of HB value in men and women?
A
16.5 in men, 16.0 in women
4
Q
What investigation do we do?
A
Bone marrow biopsy
5
Q
What are causes of polycythemia?
A
Hypoxia, tumors, and carboxyhemoglobin from smoking
6
Q
What is the treatment of choice?
A
Phlebotomy
7
Q
Explain phlebotomy?
A
We remove a unit of blood weekly, until the hematocrit is less than 45% for males, 42 for females
