Polycythemia

Question 1

How to differentiate primary polycythemia to secondary polycythemia

Answer 1

Check EPO values
Decrease EPO means primary and increased means secondary

Question 2

Causes of primary polycythemia

Answer 2

Polycythemia Vera ( JAK2 mutation)
EPO receptor mutations

Question 3

Causes of secondary polycythemia

Answer 3

Hypoxia
EPO producing tumors
Renal transplant
Androgen supplementation

Question 4

Define polycythemia

Answer 4

Hematocrit >49% in men and >48% in women