Poisonous Plants Flashcards
Chokecheery
Toxic Principle: Cyanide - inhibits mitochondrial cytochrome oxidase
C/S: bright red blood (cherry coloured) + bitter almond smell in rumen
Tx: sodium nitrite or sodium thiosulfate
Johnson Grass (Sorghum)
Toxic Principle: Cyanide - inhibits mitochondrial cytochrome oxidase
C/S: bright red blood (cherry coloured) + bitter almond smell in rumen
Tx: sodium nitrite or sodium thiosulfate
Pigweed
Rumenants
Toxic Princple: Nitrate –> nitrite –> methemoglobinemia
C/S: dark brown/chocolate coloured blood; dyspnoea, ataxia, tachycardia
Tx: 1% methylene blue
Nightshade (Solanum)
Ruminants
Toxic Princple: Nitrate –> nitrite –> methemoglobinemia
C/S: dark brown/chocolate coloured blood; dyspnoea, ataxia, tachycardia
Tx: 1% methylene blue
ALSO
Glycoalkaloid + neurotoxin (aglycone) –> anorexia, nasuea, abdominal pain, V+, D+ –> apathy, paresis/paralysis, unconciousness
Sorghum
Rumenants
Toxic Princple: Nitrate –> nitrite –> methemoglobinemia
C/S: dark brown/chocolate coloured blood; dyspnoea, ataxia, tachycardia
Tx: 1% methylene blue
Oleander
Toxic Principle: Cardiac glycoside - oleandrin + neriine
C/S: salivation, nausea, vomiting, hematochezia; bradycardia + hypotension; AV block
Tx: Induce emesis; activated charcoal; supportive care; atropine (bradycardia); isoproterenol/procainamide/quinidine (AV block)
Foxglove
Toxic Principle: Cardiac glycoside - increase contractility and decrease HR
C/S: salivation, nausea, vomiting, hematochezia; bradycardia + hypotension; AV block
Tx: Induce emesis; activated charcoal; supportive care; atropine (bradycardia); isoproterenol/procainamide/quinidine (AV block)
Lily-of-the-valley
Toxic Principle: Cardiac glycoside - increase contractility + decrease HR
C/S: salivation, nausea, vomiting, hematochezia; bradycardia + hypotension; AV block
Tx: Induce emesis; activated charcoal; supportive care; atropine (bradycardia); isoproterenol/procainamide/quinidine (AV block)
Yew
Toxic Principle: Taxine Alkaloid A + B - inhibit cardiac depolarization
C/S: salivation, nausea, vomiting, hematochezia; bradycardia + hypotension; AV block
Tx: Induce emesis; activated charcoal; supportive care; atropine (bradycardia); isoproterenol/procainamide/quinidine (AV block)
Rhododendron
Toxic Principle: Andromedotoxins - bind membrane sodium channels
C/S: salivation, nausea, vomiting, hematochezia; bradycardia + hypotension; AV block
Tx: Induce emesis; activated charcoal; supportive care; atropine (bradycardia); isoproterenol/procainamide/quinidine (AV block)
St. John’s Wort
Primary photosensitization - metabolized agent –> photodynamic
C/S - skin only; erytheme, oedema, peeling; pruritus; hyperesthesia
Rape <– thats a fucked up name for a plant
Secondary Photosensitization - impaired hepatic function –> reduce excretion of plant pigments
C/S: LIVER + SKIN; erytheme, odema, peeling; pruritus; hyperesthesia
Blue-Green Algae
Secondary Photosensitization - Hepatic failure –> reduce excretion of plant pigments –> skin lesions
C/S: LIVER + SKIN; erythema, oedema, peeling; pruritus; hyperesthesia
Groundsel
Secondary Photosensitization - Hepatic failure –> reduce excretion of plant pigments –> skin lesions
C/S: LIVER + SKIN; erythema, oedema, peeling; pruritus; hyperesthesia
Lupine
Mainly effects sheep
Teratogenic in cattle: 40-70 gestation = Crooked Calf syndrome)
Toxic principle: quinolizidine alkaloid - nicotinic effects
C/S: salivation, incoordination, head-pressing, muscle tremors (seizures), dyspnoea
Tx: none