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Y4 Gen Med > Poisoning Overdose > Flashcards

Poisoning Overdose Flashcards

1
Q

What is seen on blood tests and paracetamol overdose?

A

Raised liver enzymes, prolonged pretty sound in time

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2
Q

What is seen on ABG in paracetamol overdose?

A

Lactic acidosis

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3
Q

What is the important complication of paracetamol overdose?

A

Hepatic necrosis

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4
Q

What is seen on ABG in aspirin salicylate overdose?

A

Initially metabolic acidosis then respiratory alkalosis

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5
Q

What symptom of overdose is specific to aspirin salicylate overdose?

A

Deafness tinnitus

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6
Q

Overdose from what drug can cause yellow vision?

A

Digoxin

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7
Q

Poisoning from what can cause confusion, a tight band headache, abnormally pink mucosa and affects members of the same household?

A

Carbon monoxide

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8
Q

What effect does opioid overdose have on our RR, BP and HR?

A

All low

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9
Q

What is the management of opioid overdose?

A 
IV naloxone 
(may need multiple doses)
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10
Q

What is the management of carbon monoxide poisoning?

A

100% hyperbaric oxygen

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11
Q

What is the gold standard investigation for carbon monoxide poisoning?

A

Carboxyhemoglobin

blood test direct spectrophotometric measurement of HbCO

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12
Q

What investigation is done for antifreeze ethylene glycol ingestion?

A

Serum osmolality

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13
Q

What is the management of beta-blocker overdose?

A

Atropine if bradycardic, otherwise glucagon

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14
Q

What is the management of iron overdose?

A

Deferoxamine

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15
Q

What is the management of benzodiazepine overdose?

A

Flumazenil (only if severe)

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16
Q

What is the management of heparin overdose?

A

Protamine sulfate

17
Q

What is the management of antifreeze ethylene glycol ingestion?

A

Fomepizole

ethanol traditional Tx

18
Q

What is the management of tricyclic overdose?

A

IV fluids + IV bicarbonate

19
Q

When can activated charcoal be given in the management of overdose?

A

If within 1hr of ingestion

20
Q

What is the management of the digoxin overdose?

A

IVpotassium, IV digoxin-specific antibody fragmentsDigibind

21
Q

What is the last line management of hepatic necrosis due to paracetamol overdose?

A

Liver transplant

22
Q

What is the presentation of anticholinergic toxidrome?

A

Mydriasis, warm dry skin, urinary retention, agitation, >HR, blurred vision

23
Q

What investigations should be done for paracetamol overdose?

A

Paracetamol level, FBC, LFTs, U+E, blood glucose, CK, ABG, ECG, clotting screen

24
Q

When are paracetamol levels measured in paracetamol overdose?

A

Paracetamol level (at 4hr post ingestion

25
Q

Is the management of paracetamol overdose?

A

NAC n-acetylcysteine

use graph curve normogram

26
Q

Admission is indicated for all deliberate self poisoning - true or false

A

Yes

27
Q

What is the definition of a staggered overdose?

A

If all the tablets were not taken within 1 hour

28
Q

In paracetamol overdose, treatment is indicated if on or above the treatment line – true or false

A

True

Unless staggered overdose always give NAC

29
Q

What is the management of aspirin overdose?

A

IV bicarbonate, haemodialysis

30
Q

What is the management of warfarin overdose?

A

Vitamin K, prothrombin complex concentrate

31
Q

What is the management of methanol poisoning overdose?

A

Fomepizole or ethanol

32
Q

What is the management of cyanide poisoning?

A

Hydroxocobalamin

Y4 Gen Med (9 decks)

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