Poisoning and Toxidromes Flashcards
What are the main alterations to mental status with sympathomimetic toxins?
- Hyperalert
- Agitation
- Hallucinations
- Paranoia
How do sympathomimetics alter pupil size?
Cause myadriasis
What changes to vital signs might you see in someone with sympathomimetic intoxication?
- Hyperthermia
- Tachycardia
- Hypertension
- Widened pulse pressure
- Tachypnoea
- Hypernoea
What are examples of sympathomimetic agents?
- Cocaine
- Amphetamines
- Cathinones
- Ephidrine
- Pseudoephedrine
- Theophylline
- Caffeine
What signs might you find in someone with sympathomimetic overdose other than changes in vital signs?
- Diaphoresis
- Tremors
- Hyperreflexia
- Seizures
What alterations to mental status occur in anticholinergic overdose?
- Hypervigilance
- Agitation
- Hallucinations
- Delerium with mumbling speech
- Coma
What changes occur to pupil size due to anticholinergic overdose?
Cause myadriasis
What changes to vital signs can anticholinergic toxicity cause?
- Hyperthermia
- Tachycardia
- Hypertension
- Tachypnoea
What signs might you see in someone with anticholinergic intoxication other than the changes you would see to vital signs?
- Dry flushed skin
- Dry mucous membranes
- DEcreased bowel sounds
- Urinary retention
- myoclonus
- Choreoathetosis
- Picking behaviour
- Seizures (rare)
What are examples of anticholinergic drugs which can cause anticholinergic toxidrome?
- Antihistamines
- TCA
- Antiparkinson agents
- Antispasmodics
- Phenothiazines
- Atropine
- Cyclobenzarine
What alterations to mental status can hallucinogenic intoxication cause?
- Hallucinations
- Perceptual distrotion
- Depersonalisation
- Synesthesia
- Agitation
What is the most common type of pupil change seen in hallucinogen intoxication?
Myadriasis
What changes to vital signs can hallucinogens cause?
- Hyperthermia
- Tachycardia
- Hypertension
- Tachypnoea
What signs might you see in someone with hallucinogen intoxication other than the changes seen to their vital signs?
Nystagmus
What are examples of hallucinogenic drugs which can cause hallucinogenic toxidrome?
- Phencyclidine
- LSD
- Mescaline
- Psilocybin
- MDMA
- MDEA