Poisoning Flashcards
Bitter almonds
Cyanide
Garlic
Arsenic, thalloum, organophosphayes, selenium
Antidote for Acetamenophen
NAC
Antidote for anticholinergics:
Physostigmine
Antidote for Opioids:
Nalaxone
Antidote for Organophosphates:
Atropine, Pralidoxime
Principles of Management of a poisoned patient:
Decontamination
Enhanced elimination
Antidotes
Supportive care
The most common cause of acute liver failure
Acetamenophen toxicity
Toxic dose of Acetamenophen:
75mg/kg/ Day for cpnsecutive days
>200mg/kg in children
>7.5-10 grams in adolescents
Peak liver function abnormalities, fulminant hepatic failure and multisystem organ failure and potential death happens in which stage of Acetamenophen toxicity
Stage III, 72 tp 96Hrs
Acute toxic dose of salicylates:
> 150mg/kg
Significant salicylate toxicity:
> 300mg/kg
500mg/kg (Fatal)
In Ibuprpfen and NSAIDs poisoning. Ingestion of >400mg/kg produces these manifestations:
Altered mental status and metabolic acidosis
Toxicity upon ingestion causes hematemesis, melena,ulceration, infarction and potential perforation.
Iron Toxicity
Severe toxicity is seen in Iron ingestion if the levels are:
> 60mg/kg
